Teresa M. Coque

Bacteria chromosomes contain Genomic Islands that provide virulence, antibiotic resistance, MGE-defence,... They transfer between cells, but the mechanism of most remains elusive.

Here we explore the conjugative capacity of these mysterious Genomic Islands.

www.biorxiv.org/content/10.6...

Judge Orders Release of Minnesota Refugees Targeted in ICE Crackdown A federal judge granted a temporary restraining order, which halts a Trump administration operation that has swept up at least 100 people so far.

A federal judge on Wednesday ordered federal agents to stop detaining and deporting refugees in Minnesota who were lawfully admitted to the U.S., granting a temporary restraining order, which halts for now the Trump administration’s operation. The administration is likely to appeal the ruling.

Wikipedia is needed now more than ever, 25 years on The online encyclopedia is an antidote to an increasingly poisoned information ecosystem. Researchers should help to nourish it.

Wikipedia is needed now more than ever, 25 years on www.nature.com/articles/d41...

And what a beautiful @pnas.org cover @paularamiro.bsky.social and @jerorb.bsky.social !!!!!! You should be very proud!

Congratulations to @paularamiro.bsky.social and the @jerorb.bsky.social ´s group and collaborators! A must reading for understanding plasmid biology, bacterial evolution and evolution more broadly. Bravo! 👏👏👏 👇

YouTube video by Bruce Springsteen Bruce Springsteen - Streets Of Minneapolis (Official Audio)

I wrote this song on Saturday, recorded it yesterday and released it to you today in response to the state terror being visited on the city of Minneapolis. It’s dedicated to the people of Minneapolis, our innocent immigrant neighbors and in memory of Alex Pretti and Renee Good.

Stay free

Logran eliminar por completo tumores de páncreas en ratones utilizando una triple terapia Investigadores del Centro Nacional de Investigaciones Oncológicas (CNIO) han logrado eliminar por...

❗ Investigadores españoles logran eliminar por completo tumores de páncreas en ratones utilizando una triple terapia. Este hito alcanzado por primera vez abre la puerta a tratamientos en humanos para uno de los cánceres más mortales

1/¿Podemos detectar la meningitis con ultrasonidos e IA?

En este nuevo News From The Lab, la investigadora Sara Ajanovic (ISGLOBAL - Hospital Vall d’Hebron) nos presenta Neosonics, una innovadora herramienta que diagnostica de forma rápida y no invasiva.

bit.ly/49dNGGb

'La angustia de no tener un hogar', la carta al director de Mireia Carrillo. Puedes leer más cartas al director aquí 👉 social.elpais.com/j9vci10

19/ 🔚We have reached the end of the event!

Thank you for joining us and for your commitment to the future of health. Congratulations to all the selected projects!🎉👏

Stay tuned, we’ll be sharing more highlights and details from the ceremony soon!👀

1/ Antibiotic resistance causes ➕ than 1 M deaths each year and understanding why this happens is key to stopping it.

With #HealthResearch support, @sanmillan.bsky.social is investigating how different plasmids (DNA fragments) coexist in bacteria and confer resistance.

https://tinyurl.com/3bysv6cr

2/ 🤝 This project is carried out at @cnb-csic.bsky.social is conducted in consortium with @tmcoque.bsky.social (Instituto Ramón y Cajal de Investigación Sanitaria).

A pleasure and an honour to have received this prestigious grant with my admired colleagues and friends @sanmillan.bsky.social and @asanchezlab.bsky.social . More about AMR under plasmid lens!. My sincere gratitude to @caixaresearch.bsky.social

@microryc.bsky.social @esgem-sg.bsky.social

Nueva combinación de fármacos reduce un 40% la mortalidad en cáncer de próstata recurrente     Los hombres cuyo cáncer de próstata regresa después de una cirugía o radioterapia ahora...

❗ Descubren una nueva combinación de fármacos que reduce un 40% la mortalidad en cáncer de próstata recurrente

Maravillosa. Recuerda que la primera vez que la vi fue en el cine de bellas artes, entonces sala de arte y ensayo. Y por supuesto en versión original. Shock. Colosal todo el reparto. Ay aquella mecedora.

El asombroso fenómeno de la calidad menguante Asientos de avión cada vez más pequeños, prendas irreconocibles al segundo lavado, máquinas que te atienden por teléfono para cualquier trámite. El cuidado por las cosas bien hechas parece haber dejado de ser un valor que cuenta

Asientos de avión cada vez más pequeños, prendas irreconocibles al segundo lavado, máquinas que te atienden por teléfono para cualquier trámite. El cuidado por las cosas bien hechas parece haber dejado de ser un valor que cuenta

Ecological and evolutionary consequences of changing seasonality Climate change and other anthropogenic drivers alter seasonal regimes across freshwater, terrestrial, and marine biomes. Seasonal patterns affect ecological and evolutionary processes at different eco...

Ecological and evolutionary consequences of changing seasonality | Science

@jdtonkin.bsky.social
www.science.org/doi/10.1126/...

How to bring experimental evolution to the classroom Pupils of all ages can benefit from witnessing evolution in real time - and it’s now possible in schools, say this researcher from the University of Bath

Its here! Finally published. www.tes.com/magazine/tea...

Evolution of antivirus defense in prokaryotes depending on the environmental virus prevalence and virome dynamics Prokaryotes can acquire antivirus immunity via two fundamentally distinct types of processes: direct interaction with the virus as in CRISPR-Cas adaptive immunity systems and horizontal gene transfer ...

Cool work by Sanasar investigating how bacteria-phage dynamics affect the distribution of antiphage defense systems in the genome www.biorxiv.org/content/10.1...

Our latest preprint just dropped @paulturnerlab.bsky.social

We evolved bacteria on swim plates, against a phage that attacks through the flagellum. Motility trades off AND trades up(!!) with phage-resistance!

www.biorxiv.org/content/10.1...

New paper from my lab (first author is Sonia Ghose): www.frontiersin.org/journals/mic...

Skin microbiomes of frogs vary among body regions, revealing differences that reflect known patterns of chytrid infection

Figure 2 of the preprint

And this is also what we see experimentally! Defensive or co-invading CRISPR-Cas are always beneficial, but offensive CRISPR is severely limited by and even detrimental when there is TA.

4/6

The cover of the May issue of Trends in Microbiology, featuring several cells with cartoon figures of phages and plasmids listening to environmental cues, e.g. by fishing for signaling molecules outside their host or staring at an empty pantry shelf.

Our opinion piece on transmission timing in phages and plasmids graces the cover of @cp-trendsmicrobiol.bsky.social this month. Featuring the work of talented master student Andrina Bernhard, the illustration showcases cues that MGEs use to switch between horizontal and vertical transmission.

Genomic surveillance reveals different transmission patterns between third-generation cephalosporin and carbapenem resistance in Klebsiella pneumoniae in the Comunidad Valenciana (Spain), 2018–2020 - ... Background The emergence and spread of third-generation cephalosporins (3GC) and carbapenem-resistant Klebsiella pneumoniae pose a global critical challenge. Understanding the transmission dynamics wi...

Good papers, like good wine, need maturing. I'm proud and thrilled to share our work on genomic epidemiology of K.pneumoniae in Valencia and differential transmission patterns of resistances, part of Neris Garcia's PhD thesis and the NLSAR consortium. go.uv.es/td8iL4c #publichealth #EpiSky 🧬🖥️

Stenotrophomonas maltophilia exhibits defensive multicellularity in response to a Pseudomonas aeruginosa quorum sensing molecule Microorganisms commonly exist in polymicrobial communities, where organisms can respond to interspecies secreted molecules by altering behaviors and physiology, however, the underlying mechanisms rema...

New preprint alert 🚨: We found that Steno maltophila senses a quorum sensing molecule from the co-infecting pathogen Pseudomonas aeruginosa and switches to multicellular aggregates as a protective mechanism. #MicroSky
www.biorxiv.org/content/10.1...

Calling all evolutionary biologists! 👇👇👇

Dr. Anthony Fauci urges Americans not to accept "Normalization of Untruths".

Biofilm architecture determines the dissemination of conjugative plasmids | PNAS Plasmid conjugation is a contact-dependent horizontal gene transfer mechanism that significantly contributes to the dissemination of antibiotic res...

Biofilm architecture determines the dissemination of conjugative plasmids: We measured the spatiotemporal spread of plasmids in biofilms and found that plasmids only spread in some biofilm regions!

Collab with lab of @sbigot.bsky.social & Christian Lesterlin
www.pnas.org/doi/10.1073/...

“Calamity Jane” performed by Doris Day ( Juanita Calamidad in spanish) A musical movie very very popular among spanish community @wvschaik.bsky.social

Major European institutes join race to save US science data As the administration of US President Donald Trump slashes budgets, crucial climate and other data sets could disappear.

Several research institutes in Germany are joining a worldwide grassroots effort to save science data sets that researchers fear could be deleted by US President Donald Trump’s administration, Nature has learnt.

https://go.nature.com/42uEw50