's Avatar

@roop-dhillon.bsky.social

PhD Student | University of Birmingham | Archaea Enjoyer | Microbiomes

68 Followers  |  117 Following  |  11 Posts  |  Joined: 01.03.2025  |  2.2465

Latest posts by roop-dhillon.bsky.social on Bluesky

From the Aegean Bronze Age, Minoan clay vessels with black handpainted decoration.on a pale biscuity-coloured slip

Top left - clay flask decorated in Minoan ‘Marine Style’’ with an octopus with tentacles writhing around the body of the vase. Additional motifs such as seaweed and rocks represent the seabed. From Palaikastro, 1500-1450 BC

Top right - clay rhyton in the shape of a bull’s head. A rhyton is a type of pouring vessel used for filling cups or making liquid offerings. There is a pouring hole at the bull’s mouth. From Knossos Little Palace, 1450-1375 BC

Bottom left - Nautilus vessel - clay rhyton depicting the seabed with nautili, corals and seaweed. From Phaistos Palace, 1500-1450 BC

Bottom right - Basket shaped rhyton decorated with double-axe motif. There is a small pouring hole in one of the bottom corners. From Pseira, 1500-1450 BC

From the Aegean Bronze Age, Minoan clay vessels with black handpainted decoration.on a pale biscuity-coloured slip Top left - clay flask decorated in Minoan ‘Marine Style’’ with an octopus with tentacles writhing around the body of the vase. Additional motifs such as seaweed and rocks represent the seabed. From Palaikastro, 1500-1450 BC Top right - clay rhyton in the shape of a bull’s head. A rhyton is a type of pouring vessel used for filling cups or making liquid offerings. There is a pouring hole at the bull’s mouth. From Knossos Little Palace, 1450-1375 BC Bottom left - Nautilus vessel - clay rhyton depicting the seabed with nautili, corals and seaweed. From Phaistos Palace, 1500-1450 BC Bottom right - Basket shaped rhyton decorated with double-axe motif. There is a small pouring hole in one of the bottom corners. From Pseira, 1500-1450 BC

Marvellous Minoan clay vessels made by creative potters on the island of Crete during the Aegean Bronze Age around 3,500 years ago! 🤩

Heraklion Archaeological Museum 📷 by me

#Archaeology

11.10.2025 11:05 — 👍 736    🔁 211    💬 14    📌 15
Matters Microbial #108: Neanderthal Oral Health, Ancient Bacteria and DNA
YouTube video by MicrobeTV Matters Microbial #108: Neanderthal Oral Health, Ancient Bacteria and DNA

This week, Dr. Laura Weyrich, Associate Professor of Anthropology at Pennsylvania State University, joins the #QualityQuorum to discuss the paleo oral microbiome! We will learn if our ancestors had the same kind of resident microbes as we do.
@markowenmartin.bsky.social @lauraweyrich.bsky.social

19.09.2025 14:08 — 👍 15    🔁 6    💬 1    📌 0
Preview
Horizontal gene transfer of the functional archaellum machinery to Bacteria Motility in Archaea is driven by a nanomachinery called the archaellum. So far, archaella have been exclusively described for the archaeal domain; however, a recent study reported the presence of arch...

Would you expect that Bacteria use an archaellum for swimming? We didn't, but we found that some Chloroflexota do! Find the story here: www.biorxiv.org/content/10.1...

A little thread below 1/n

03.02.2025 10:08 — 👍 126    🔁 58    💬 1    📌 5
Post image

Excited to present my work at poster #82 at #EESMicrobiome today! Come round and talk RNA viruses with me

18.09.2025 09:02 — 👍 9    🔁 1    💬 0    📌 0
Post image Post image Post image Post image

☀️ Good morning from Day 3 of #EESMicrobiome 🦠

☕🥨 Fuelled by coffee and pretzels, we’re starting strong with Session 4: Microbiome–host interactions in health and disease.

🎤 'Understanding gut-to-host communication to prevent cardiovascular disease' by @fzmarques.bsky.social (Monash University)

18.09.2025 07:39 — 👍 8    🔁 2    💬 1    📌 1
Post image Post image Post image Post image

Welcome to the EMBO | EMBL Symposium ‘The human microbiome’ 🦠🙌🏼
With a growing crowd on site, it is time for the opening remarks – #EESMicrobiome Day 1, let’s go! 🤩

16.09.2025 14:38 — 👍 6    🔁 2    💬 0    📌 0

Happy to see this paper finally out in @pnas.org!

#phage #microbiology #MicroSky #VirEvol 🦠 🧫 🔬

Gift link: www.pnas.org/eprint/YYDZ9...

08.09.2025 19:51 — 👍 67    🔁 22    💬 3    📌 1
Preview
A mammoth toothache: bacterial community discovered in mouth of ancient mammal Genetic-sequencing techniques have uncovered the oldest host-associated microbial DNA ever recorded — inside samples of teeth and bones from woolly and steppe mammoths.

This study describes the oldest microbial DNA ever sequenced

go.nature.com/4nfIzcU

05.09.2025 12:23 — 👍 46    🔁 8    💬 0    📌 2
Preview
Blood-borne immune cells carry low biomass DNA remnants of microbes in patients with colorectal cancer or inflammatory bowel disease The involvement of the intestinal microbiome in the pathogenesis of inflammatory bowel disease (IBD) and colorectal cancer (CRC), is well-established. Bacteria interact with immune cells at sites o...

Interesting paper.

Authors ruled out contamination; are not claiming 'blood microbiome', but rather 'DNA remnants'

'Blood-borne immune cells carry low biomass DNA remnants of microbes in patients with colorectal cancer or inflammatory bowel disease'

www.tandfonline.com/doi/full/10....

21.07.2025 14:20 — 👍 10    🔁 4    💬 0    📌 1
Preview
Our body is a mosaic of fungi. Some scientists think they could be influencing our brain The fungi within our bodies may have a much greater effect on our health than we've long given them credit for.

New BBC article on fungal infections in which we are quoted:
www.bbc.co.uk/future/artic...

22.07.2025 06:44 — 👍 11    🔁 3    💬 0    📌 0
A cartoon depiction of the Asgard archaeon Skadiarchaeum sp., named after the Norse goddess of skiing and hunting, Skadi.

A cartoon depiction of the Asgard archaeon Skadiarchaeum sp., named after the Norse goddess of skiing and hunting, Skadi.

In a couple of days, my grad student Stavros Trimmer will present his new Asgard archaea culture at the GRC Archaea. He named it Skadiarchaeum after Skadi, the Norse goddess of skiing and hunting. Cartoon of Skadi based on cryoET, which was performed together with with @florianwollweber.bsky.social

19.07.2025 16:15 — 👍 63    🔁 11    💬 7    📌 0
Preview
Superbugs could kill millions more and cost $2tn a year by 2050, models show Exclusive: Research on burden of antibiotic resistance for 122 countries predicts dire economic and health outcomes

Meanwhile the news.

To learn more about antibiotic-resistant superbugs visit our educational website or come to our pop-up shop in Cardiff.

21.07.2025 07:25 — 👍 5    🔁 7    💬 0    📌 0
Post image

💥 Excited to introduce Bacformer 🦠 - the first foundation model for bacterial genomics. Bacformer represents genomes as sequences of ordered proteins, learning the “grammar” of how genes are arranged, interact and evolve.

Preprint 📝: biorxiv.org/content/10.1...

🧵 1/n

21.07.2025 09:55 — 👍 91    🔁 59    💬 3    📌 2
Preview
Experimental evolution in an era of molecular manipulation Nature Reviews Genetics, Published online: 21 July 2025; doi:10.1038/s41576-025-00867-6In this Review, Ascensao and Desai discuss how methodological advances in genotype and phenotype manipulation are transforming experimental evolution approaches and providing new insights into the underlying genetics and forces that shape phenotypic evolution.

New online! Experimental evolution in an era of molecular manipulation

21.07.2025 14:45 — 👍 21    🔁 4    💬 1    📌 1
Preview
A caged drug enables precision delivery “GlycoCaging” uses gut bacteria to activate drugs for inflammatory bowel disease

“GlycoCaging” uses gut bacteria to activate drugs for inflammatory bowel disease.

Learn more in a new #SciencePerspective: scim.ag/4ltfMk8

07.07.2025 13:31 — 👍 81    🔁 9    💬 0    📌 1
Study design to capture the dynamic nature of early microbiome and brain development. (A) Study design; participants (N = 194) were seen up to three times over the first 18 months of life. Stool samples and EEG data were collected, generating microbial functional profiles (stool) and VEP waveforms (EEG) used in subsequent analyses. Analyses included generalized linear models (GLM) and feature set enrichment analysis (FSEA). (B) Longitudinal sampling of study participants; density plots (top) for stool and EEG collection show the ages represented in each visit. The scatter plot (bottom) shows individual participant visits. Dotted lines connect separate visits for the same participant. When stool and EEG data were collected for the same visit (purple) but not on the same day, the dot represents the median age of collection, and vertical bars in blue and red represent stool and EEG collections, respectively.

Study design to capture the dynamic nature of early microbiome and brain development. (A) Study design; participants (N = 194) were seen up to three times over the first 18 months of life. Stool samples and EEG data were collected, generating microbial functional profiles (stool) and VEP waveforms (EEG) used in subsequent analyses. Analyses included generalized linear models (GLM) and feature set enrichment analysis (FSEA). (B) Longitudinal sampling of study participants; density plots (top) for stool and EEG collection show the ages represented in each visit. The scatter plot (bottom) shows individual participant visits. Dotted lines connect separate visits for the same participant. When stool and EEG data were collected for the same visit (purple) but not on the same day, the dot represents the median age of collection, and vertical bars in blue and red represent stool and EEG collections, respectively.

Leveraging longitudinal data from 194 infants across the first 18 months of life, researchers show that microbial genes encoding neuroactive compounds are associated with visual cortical neurodevelopment. Read the article in #mBio: asm.social/2uo

07.07.2025 16:37 — 👍 2    🔁 2    💬 1    📌 0
Model for the interaction between P. aeruginosa and K. pneumoniae. These bacteria can co-exist in nutrient-replete conditions. Under iron-limiting conditions, siderophore synthesis is induced in both bacteria. Iron limitation can also turn on the synthesis of biosurfactants, rhamnolipids, in P. aeruginosa, allowing it to push away K. pneumoniae.

Model for the interaction between P. aeruginosa and K. pneumoniae. These bacteria can co-exist in nutrient-replete conditions. Under iron-limiting conditions, siderophore synthesis is induced in both bacteria. Iron limitation can also turn on the synthesis of biosurfactants, rhamnolipids, in P. aeruginosa, allowing it to push away K. pneumoniae.

#MicrobiologyMonday: Pseudomonas aeruginosa releases a surfactant that displaces Klebsiella pneumoniae from solid surfaces. By pushing K. pneumoniae away, the detergent allows P. aeruginosa to better compete for limited iron. Learn more in #mBio: asm.social/2sH

16.06.2025 17:57 — 👍 21    🔁 8    💬 1    📌 1
Post image Post image

Half way through the IMI Summer school 2025 starts with a fantastic Q&A panel with our own UoB students and Postdocs and @wvschaik.bsky.social giving a great talk on AMR & Phages 🦠🦠

02.07.2025 12:30 — 👍 5    🔁 3    💬 2    📌 0
Post image Post image Post image Post image

How does your diet impact the microbiome? Let's find out...🦠🦠

02.07.2025 14:05 — 👍 5    🔁 2    💬 0    📌 0
Post image Post image Post image Post image

Some exciting results from the IMI Summer school experiments 🧪🧫🔬

03.07.2025 13:55 — 👍 6    🔁 1    💬 1    📌 0

great training for grant applications

25.04.2025 13:23 — 👍 1    🔁 0    💬 1    📌 0

schaechter.asmblog.org/schaechter/2...
#MicroSky #Archaea #ArchaeaSky #SymbioSky

14.04.2025 10:29 — 👍 7    🔁 8    💬 2    📌 1
Post image

Excited to announce the EMBO Conference: Molecular Biology of Archaea (MBoA) 2026!
Join us in Cambridge, UK, from 6–10 July 2026 for the only international meeting dedicated entirely to Archaea.

22.04.2025 08:26 — 👍 25    🔁 16    💬 2    📌 0
Growth of public metagenomes over time

Growth of public metagenomes over time

A 1.0 release for Sandpiper. 700,000 microbial community profiles (3x the last version, 4.7 Pbp metaG), searchable via the @ace-gtdb.bsky.social R226 taxonomy that just dropped. MetaGs are going exponential, but we are still nowhere near a MAG for all species. sandpiper.qut.edu.au #microsky 🧬🖥️ 1/2

17.04.2025 11:06 — 👍 49    🔁 34    💬 3    📌 1
Preview
Ross's fundraiser for Cancer Research UK Help Ross McInnes raise money to support Cancer Research UK

I am raising money for Cancer Research UK by walking 23 miles in the Kiltwalk Mighty Stride on the 27th of April. Any donations would be greatly appreciated! www.justgiving.com/page/ross-mc...

17.04.2025 08:16 — 👍 5    🔁 2    💬 0    📌 0
Risograph style picture of yellow chemical structures representative of gut bacterial metabolites marching across a tube station platform onto a red train, where they are silhouetted in the windows. Pink and purple microbes with yellow/orange windows are in the distance. The tube station is called gut central, and it's on the circulation line.

Risograph style picture of yellow chemical structures representative of gut bacterial metabolites marching across a tube station platform onto a red train, where they are silhouetted in the windows. Pink and purple microbes with yellow/orange windows are in the distance. The tube station is called gut central, and it's on the circulation line.

How do microbial metabolites influence host physiology? They hop on the circulation line, obvs... (WIP)
#sciart #microsky 🧪

17.04.2025 08:19 — 👍 85    🔁 13    💬 2    📌 0
Transcription 1: Archaeal RNA Polymerase
YouTube video by Archaeal Adventures Transcription 1: Archaeal RNA Polymerase

New Video up on my YouTube Channel all about Archaeal RNA Polymerase, and how it differs to eukaryotic and bacterial RNAP 🧪

youtu.be/H2tPufQ8tEw

14.04.2025 17:51 — 👍 7    🔁 1    💬 0    📌 0
Preview
An energetic framework for gut microbiome-mediated obesity induced by early-life exposure to antibiotics Schell and Carmody explore how early-life antibiotic exposure influences obesity risk via effects on the gut microbiome. They discuss how high doses temporarily impair energy gain by disrupting beneficial microbial activity, while low doses may enhance energy storage, offering insights into long-term health impacts of antibiotics and their evolutionary significance.
10.04.2025 11:54 — 👍 1    🔁 1    💬 0    📌 0
Video thumbnail

ᗩᑎTIᗷIOTIᑕ ᖇEᔕIᔕTᗩᑎᑕE ᑌᑭᗪᗩTE

EPIC BATTLE IN SCOTLAND 🏴󠁧󠁢󠁳󠁣󠁴󠁿

WHISKEY 🥃 vs E COLI 🦠

no doubt works even for carbapenem-resistant strains of sequence type 131 carrying extended-spectrum beta-lacatamase CTX-M-15

#AMR #SingleMalt

10.04.2025 12:26 — 👍 63    🔁 10    💬 9    📌 5
Preview
Bacteriocin production facilitates nosocomial emergence of vancomycin-resistant Enterococcus faecium - Nature Microbiology Genomic and functional analyses of healthcare-associated vancomycin-resistant Enterococcus faecium reveal that bacteriocin T8 is enriched in emergent lineages and provides a competitive advantage in v...

Excited to share our latest, out today in @naturemicrobiol.bsky.social Bacteriocin production facilitates nosocomial emergence of vancomycin-resistant Enterococcus faecium www.nature.com/articles/s41... @idpittstop.bsky.social

21.03.2025 13:45 — 👍 111    🔁 54    💬 13    📌 3

@roop-dhillon is following 20 prominent accounts