Géraldine Laloux

Bacterial cell wall & periplasm paradigm shift - important read #MicroSky

www.nature.com/articles/s41...

Chromosome enthusiasts, York is calling!

Join us at The Biology & Physics of Chromosomes www.eventsforce.net/biochemsoc/f...

Late breaking abstract deadline
📆 7 August

@biophychrom.bsky.social @vslioy.bsky.social @damelab.bsky.social @graingerlab.bsky.social @biochemsoc.bsky.social #microsky

Thanks, Basile! All figures were drawn manually ✏️ 🖌️ by Coralie! @coralietesseur.bsky.social

Strategies and mechanisms of contact-dependent predation in bacteria Predatory bacteria kill other bacteria to acquire nutrients. Among diverse strategies to kill and feed on prey, contact-dependent predation stands out…

#MicroSky Summer read!

Predatory bacteria kill and eat other bacteria. Their deadly actions come in many flavors, often via direct physical contact between predator &
prey 🧛

How do they do it?
Our review 📖 @coralietesseur.bsky.social @ysantin.bsky.social

www.sciencedirect.com/science/arti...

Congrats to first author of both chapters @coralietesseur.bsky.social as well as @remyophe.bsky.social and @ysantin.bsky.social

a man wearing sunglasses and a white t-shirt is holding something in his hands . ALT: a man wearing sunglasses and a white t-shirt is holding something in his hands .

We wrote 2 📕 chapters with tips & tricks to identify protein-protein interactions in bacteria 🦠

1) In vivo proximity labeling with miniTurbo link.springer.com/protocol/10....

2) An adapted polar recruitment assay feat. E. coli as a test tube link.springer.com/protocol/10.....

Enjoy #MicroSky 🧪

Please repost: PhD position with my lab and @weisslab.bsky.social in a great collaboration on bacterial adhesion #microsky. See drive.google.com/file/d/1GJD4...

#MicroSky

A bacterial CARD-NLR immune system controls the release of gene transfer agents Bacteria have evolved a wide array of immune systems to detect and defend against external threats including mobile genetic elements (MGEs) such as bacteriophages, plasmids, and transposons. MGEs are ...

1/ Excited to share our latest work on gene transfer agents (GTAs) in Caulobacter crescentus, led by Emma Banks in collaboration with Pavol Bardy and Mai Nguyen from York!!! See a brief thread below.
shorturl.at/o6S1w

#Postdoc position - at the University of Marburg (Germany), funded within our ERC Advanced Grant "C-SWITCH"

Focus: CTP-dependent molecular switches as a new principle of cellular regulation in bacteria (including bacteriophages)

Apply by 04 May: stellenangebote.uni-marburg.de/jobposting/2...

I’m very happy to share our latest work on the ParABS system. We investigated the dynamic interaction between the ATPase ParA and the CTPase ParB mediating chromosome segregation in Myxococcus xanthus. I would like to thank all the people involved.

Please repost: Postdoc position in antibiotic discovery in a large multidisciplinary project combining high-throughput approaches, microscopy, AI, and hit-to-lead optimization at @umontreal.ca and @mila-quebec.bsky.social. Apply to ML.Antibiotics@gmail.com. See
lnkd.in/dVVk4N3s. #microsky

Future Directions of the Prokaryotic Chromosome Field In September 2023, the Biology and Physics of Prokaryotic Chromosomes meeting ran at the Lorentz Center in Leiden, The Netherlands. As part of the workshop, those in attendance developed a series of ....

In @molecularmicro.bsky.social: two special issues on Prokaryotic Chromosome Organization. Many excellent contributions, including a vision article: 'Future directions of the Prokaryotic Chromosome Field', outcome of BioPhyChrom 2023 @biophychrom.bsky.social onlinelibrary.wiley.com/doi/10.1111/...

A million thanks to the ERC for the opportunity to explore bacterial predatory attacks and cell cycle switches with our VAMPIRE Consolidator grant @deDuveInstitute @UCLouvain_be @frsFNRS 🦠 🔬 🧛

2 days left. Asst/Assoc Prof position in bacteriology, Université de Montréal. Deadline ***Nov. 15*** come join our growing community of bacteriologists. BTW Canada is the USA’s Bluesky!

New job offer: we search a postdoc (bioinformatics) to work on mobile genetic elements and gene flow in bacteria, with a focus on antibiotic resistance within a consortium including bioinformatics, synthetic biology, epidemiology & biochemistry. See research.pasteur.fr/en/job/postd... #MicroSky

Former PhD student Ophélie Remy and I are cell poles enthusiasts, so we were delighted to offer a brief perspective on bacterial polarity for the Special Issue on Cell and tissue polarity in the Journal of Cell Science. journals.biologists.com/jcs/article-.... #MicroSky

#MicroSky

Our last story on cell polarity in Bdellovibrio bacteriovorus is now published in Journal of Bacteriology! Feat. a protein that marks the "head" of future daughter cells before non-binary division, a new DivIVA pattern, and 1st use of proximity labeling in Bdello!
journals.asm.org/doi/10.1128/...

Archaeal and bacterial cell division: Beyond the Z-ring The objective of this EMBO Workshop is to discuss advances in prokaryotic cell division. Most archaea and bacteria divide using a ring-structure formed by the tubulin homologue FtsZ, the Z-ring. Rese�...

cell divisionist take note 👇

meetings.embo.org/event/24-z-r...

MRC- funded PhD project at the interface between biology & physics to investigate the segregation of an antibiotic resistant plasmid. Interdisciplinary training with super supportive supervisors.

In the beautiful historic city of York.

Please re-post, thanks! #microsky
🦠🧫🧪
📆17 December

RomR and DivIVA appear as polar "hubs" with their own unique proximity network including known partners but also uncharacterized proteins – many new projects in sight! Great team work with Yoann Santin, Coralie Tesseur, Jovana Kaljevic from our lab. We hope you will enjoy reading it!

To unveil the proteins that RomR and DivIVA might recruit to polarize the cell, we teamed up with Petra Van Damme (UGhent) to perform miniTurbo-mediated proximity labelling (first time in Bdello!)...

...and found that they display distinct dynamics throughout the predatory lifecycle of Bdellovibrio. RomR notably labels the *future* anterior poles in the mother filamentous cell *before* it divides – and it does so during a precise time window ⏰

To add a bit more flavor, we studied this question in Bdellovibrio bacteriovorus, a predatory bacterium that grows like a spaghetti inside another bacterium 🍝. We focused on two proteins that localize to the cell poles, RomR and DivIVA...

New preprint! We delved into how bacterial cells establish their polarity, a task that is even more challenging when they produce >2 daughter cells by non-binary division: how to distinguish the head and the tail in all these progenies? www.biorxiv.org/content/10.1... #MicroSky

🧫The lab is on a roll! 🦠How do you work out what's front & back when cells don't divide in two but in roughly 2-21? read
Ophelie's quest to find clues --> www.biorxiv.org/content/10.1...

Vampire bacteria strike back in this new inspiring piece by @christophstc.bsky.social for @stcmicrobeblog.bsky.social #MicroSky

A vampire-themed perspective on our recent preprint 🧛, written by Christoph @christophstc.bsky.social for the fantastic microbiology blog "Small Things Considered" @stcmicrobeblog.bsky.social. Link to the blog post below👇 and to our preprint here 👉 www.biorxiv.org/content/10.1... #MicroSky

And tagging #MicroSky 🦠 🧫