Géraldine Laloux

Fantastic thread and data by @brunlabcaulo.bsky.social on how a single ATPase powers opposite pilus extension/retraction activities.

Just got word that we are a go for the Bacterial Cell Biology and Development GRS and GRC at Southern New Hampshire University!

GRS will be on June 5-6, 2027

GRC will be from June 6-11, 2027

Block off your calendars Prokaryotic Cell Biologists!

More details to come! Please repost!

Selective elimination of donor bacteria enables global profiling of plasmid gene expression at early stages of conjugation Abstract. Conjugative plasmids are a major driving force for the dissemination of antimicrobial resistance. During conjugation, plasmid DNA is transferred

academic.oup.com/nar/article/... Collaboration with Y. Yamaichi. Killing donor bacteria in conjugation mixes using water enables transcriptomic profiling of early plasmid genes ! Superb tool for studying zygotic induction of these early genes, which include anti-SOS and anti-RM factors. #microsky

Editorial: society journals matter—supporting science through renewed commitment Scientific publishing is in flux. Commercial publishers have expanded their influence, driven by profit margins and citation metrics. At the same time, a g

Your societies need you #MicroSky! Editorial from the European Academy of Microbiology Task Force: Society journals matter—supporting science through renewed commitment: academic.oup.com/microlife/ar...

Versatile NTP recognition and domain fusions expand the functional repertoire of the ParB-CTPase fold beyond chromosome segregation | PNAS Nucleotide triphosphate (NTP)-dependent molecular switches regulate essential cellular processes by cycling between active and inactive states thro...

Our preprint is now published in PNAS! This came together thanks to a great collaboration with Antoine Hocher and a strong team effort from the Le Lab. Thank you to the reviewers and to everyone who helped improve it. I hope ParB aficionados will enjoy it.

www.pnas.org/doi/10.1073/...

Apply now to attend the next EMBO Bacterial Networks meeting #EMBOBacNet

🗓️13-18 September 2026
📍Sant Feliu de Guixols, Spain

📝Program and registration info: meetings.embo.org/event/26-bac...

👩‍🔬Organised with co-chair @s-lab.bsky.social and ECR @coralietesseur.bsky.social

#MicroSky

The diderm cell envelope is not a stack of layers but a unified scaffold of Inner Membrane–Peptidoglycan–Outer Membrane.
We discuss how tethering the OM to the PG in E. coli preserves integrity — and extend the concept across diderm bacteria.
Curr Opin Microbiol: doi.org/10.1016/j.mi...
#microsky 🔬

Great collaboration with @guo-lab.bsky.social to determine an in situ architectural model of the Tad pilus machine. Be on the lookout soon for a preprint on the same topic by Grant Jensen and @viollierpat.bsky.social. #microsky

📢 Postdoc position: Cell Biology of Cyanobacteria

in my group, as part of the Excellence Cluster "Microbes for Climate" (M4C) in Marburg, Germany.

More information at shorturl.at/wNnDT (see Project 2)

🔗Apply at shorturl.at/VsEDl
📅Deadline: Nov 16, 2025

Please repost. #Postdoc

#MicroSky

Versatile NTP recognition and domain fusions expand the functional repertoire of the ParB-CTPase fold beyond chromosome segregation https://www.biorxiv.org/content/10.1101/2025.10.10.680097v1

Happy to finally show our story of the connection between nucleoid conformation, transcription & predation in our favorite predator Bdellovibrio bacteriovorus. 🧵 1/n

Experiments and analysis led by former post-doc @vrrenske.bsky.social in collaboration with @tunglejic.bsky.social & @rkoszul.bsky.social teams

Dynamics and interplay of gene expression and chromosome organization across a predatory lifecycle The obligate predatory bacterium Bdellovibrio bacteriovorus alternates between a motile attack phase and a growth phase inside another bacterium, during which it undergoes multiple rounds of DNA repli...

📝New preprint! #MicroSky

🕰️We chart the full, synchronized lifecycle of a predatory bacterium using Hi-C, RNA-seq, ChIP-seq & microscopy.

🧬We uncover dramatic shifts in nucleoid architecture & transcription, tightly coordinated with predation.

www.biorxiv.org/content/10.1...

🇪🇺 Smooth publishing experience with #microLife, the new @femsjournals.bsky.social journal of the European Academy for Microbiology.

🙏 @erc.europa.eu, F.R.S-FNRS & WEL-RI for support
4/4

🛠️This is the result of a long and careful work conducted by our research tech Charles de Pierpont, with help from PhD student Benoît Derneden and former lab member @remyophe.bsky.social, and validation by the whole team
3/4

🍝 Featuring the reversible spaghetti phenotype of #FtsZ -depleted Bdellovibrio: predator cell division is not required to exit the prey
2/4

Expanding the genetic toolbox of the obligate predatory bacterium Bdellovibrio bacteriovorus with inducible gene expression and CRISPR interference Inducible gene expression and CRISPR interference-mediated depletion in the predatory bacterium Bdellovibrio bacteriovorus.

🚨New paper out! #MicroSky
Studying obligate predators like Bdellovibrio bacteriovorus is tricky—essential genes for predation are also essential for survival.
We expanded its genetic toolbox:
🧬promoters to fine-tune expression
🧬IPTG-inducible system
🧬CRISPRi for rapid knockdown
bit.ly/46GUn2c
1/4

#MicroSky

Another great contribution to the “Cell Regulation” themed issue of Current Opinion in Microbiology www.sciencedirect.com/special-issu...

Out Of The Blue, It Came To Me

Inspiring “behind the paper” story here 👉 communities.springernature.com/posts/out-of... #MicroSky

Bacterial cell wall & periplasm paradigm shift - important read #MicroSky

www.nature.com/articles/s41...

Chromosome enthusiasts, York is calling!

Join us at The Biology & Physics of Chromosomes www.eventsforce.net/biochemsoc/f...

Late breaking abstract deadline
📆 7 August

@biophychrom.bsky.social @vslioy.bsky.social @damelab.bsky.social @graingerlab.bsky.social @biochemsoc.bsky.social #microsky

Thanks, Basile! All figures were drawn manually ✏️ 🖌️ by Coralie! @coralietesseur.bsky.social

Strategies and mechanisms of contact-dependent predation in bacteria Predatory bacteria kill other bacteria to acquire nutrients. Among diverse strategies to kill and feed on prey, contact-dependent predation stands out…

#MicroSky Summer read!

Predatory bacteria kill and eat other bacteria. Their deadly actions come in many flavors, often via direct physical contact between predator &
prey 🧛

How do they do it?
Our review 📖 @coralietesseur.bsky.social @ysantin.bsky.social

www.sciencedirect.com/science/arti...

Congrats to first author of both chapters @coralietesseur.bsky.social as well as @remyophe.bsky.social and @ysantin.bsky.social

a man wearing sunglasses and a white t-shirt is holding something in his hands . ALT: a man wearing sunglasses and a white t-shirt is holding something in his hands .

We wrote 2 📕 chapters with tips & tricks to identify protein-protein interactions in bacteria 🦠

1) In vivo proximity labeling with miniTurbo link.springer.com/protocol/10....

2) An adapted polar recruitment assay feat. E. coli as a test tube link.springer.com/protocol/10.....

Enjoy #MicroSky 🧪

Please repost: PhD position with my lab and @weisslab.bsky.social in a great collaboration on bacterial adhesion #microsky. See drive.google.com/file/d/1GJD4...

#MicroSky

A bacterial CARD-NLR immune system controls the release of gene transfer agents Bacteria have evolved a wide array of immune systems to detect and defend against external threats including mobile genetic elements (MGEs) such as bacteriophages, plasmids, and transposons. MGEs are ...

1/ Excited to share our latest work on gene transfer agents (GTAs) in Caulobacter crescentus, led by Emma Banks in collaboration with Pavol Bardy and Mai Nguyen from York!!! See a brief thread below.
shorturl.at/o6S1w