3DSIG

Structural bioinformaticians are exchanging ideas in Liverpool at #ISMBECCB2025.

🗣️ Wondering what they are talking about?

...chromatin modeling...
📖 pubmed.ncbi.nlm.nih.gov/40236036/
💻 github.com/SFGLab/Repli...

Thanks @3dsig.bsky.social for sharing!

Thanks a lot for your presence Prof. Adrian. #ISMB_ECCB2025 #3DSIG

PDBe is at #ISMBECCB2025!

Structural Bioinformaticians & Computational Biologist sharing insight & inc. research on:

...predicting protein thermostability change upon mutation...
📖 OrgNet: pubmed.ncbi.nlm.nih.gov/40662839/

Conference Abstracts:
🔗 www.iscb.org/ismbeccb2025...

@iscb.bsky.social

Structural bioinformaticians are exchanging ideas in Liverpool at #ISMBECCB2025 (@iscb.bsky.social).

🗣️ Wondering what they are talking about?

Conference Abstracts:
🔗 www.iscb.org/ismbeccb2025...

Thanks @3dsig.bsky.social for sharing!

PDBe is at #ISMBECCB2025!

Structural Bioinformaticians & Computational Biologist sharing insight & inc. research on:

...structure-based drug design...
📖 DrugHive: pubmed.ncbi.nlm.nih.gov/38187658/
💻 github.com/jssweller/Dr...

Thanks @3dsig.bsky.social #3DSIG for sharing!

PDBe is at #ISMBECCB2025!

Structural Bioinformaticians & Computational Biologist sharing insight & inc. research on:

...protein complexes...
📖 AlphaPulldown2: pubmed.ncbi.nlm.nih.gov/40088942/
💻 github.com/KosinskiLab/...

Thanks @3dsig.bsky.social #3DSIG for sharing!

Throughout the day, we've had amazing oral presentations. Here are some highlights! Our track has an intense second day, full of high-quality science and inspiring research.
@iscb.bsky.social
#ISMB_ECCB2025 #3DSIG @gonzaparra.bsky.social

We’ve kicked off the second and final day of the #3DSIG track with the third keynote speaker Dr. Diego Ulises Ferreiro: "A (bio)computational perspective on protein folding, function and evolution." @gonzaparra.bsky.social @diegulise.bsky.social #3DSIG #ISMB_ECCB2025 @iscb.bsky.social

And the last oral presentation of this first day with Clément Bernard: "RNA-TorsionBERT: leveraging language models for RNA 3D torsion angles prediction".
@iscb.bsky.social
#ISMB_ECCB2025 #3DSIG

The penultimate presentation of the day, with Sevastianos Korsak:"Chromatin as a Coevolutionary Graph: Modeling the Interplay of Replication with Chromatin Dynamics". @iscb.bsky.social #ISMB_ECCB2025 #3DSIG

We are approaching the end of today’s session. This is the ninth presentation of the day.
"From GWAS to Protein Structures: Illuminating Stress Resistance in Plants" by Su Datt Lam. @iscb.bsky.social
#ISMB_ECCB2025 #3DSIG

The eighth oral presentation of today is with Justas Dapkunas with: "PPI3D clusters: non-redundant datasets of protein-protein, protein-peptide and proteinnucleic acid complexes, interaction interfaces and binding sites" @iscb.bsky.social

#ISMB_ECCB2025 #3DSIG

The seventh oral presentation of today with Michel van Kempen: "Extending 3Di: Increasing Protein Structure Search Sensitivity with a Complementary Alphabet" @iscb.bsky.social #ISMB_ECCB2025 #3DSIG

After break time. Sixth oral presentation of the day. Dmitry Molodenskiy: AlphaPulldown2—a general pipeline for high-throughput structural modeling. @iscb.bsky.social

#ISMB_ECCB2025 #3DSIG

Thanks for sharing the event!

Fifth oral presentation with Dr. Remo Rohs: "Molecular design and structurebased modeling with generative deep learning" #3DSIG #ISMBECCB2025 @iscb.bsky.social

Fourth oral presentation with Ali Baran: "FlowProt: Classifier-Guided Flow Matching for Targeted Protein Backbone Generation in the de novo DNA Methyltransfarase Family" #3DSIG #ISMBECCB2025 @iscb.bsky.social

Please welcome to our Second Keynote Speaker, Prof. Adrian Mulholland - University of Bristol: "Simulations in the age of AlphaFold: dynamics, drug resistance and enzyme design". #3DSIG #ISMBECCB2025 @iscb.bsky.social @adrianmulholla1.bsky.social

The third oral presentation in #3DSIG with Petr Popov: "OrgNet: Orientation-gnostic protein stability assessment using convolutional neural networks." #ISMBECCB2025 @iscb.bsky.social

Following this presentation, we'll break for lunch 🍲 and return shortly after.

The second oral presentation in #3DSIG with Zhidian Zhang: "Probing Homo-Oligomeric Interaction Signals in Protein Language Models" @iscb.bsky.social #ISMBECCB2025

The first oral presentation in #3DSIG with Meghan Kshirsagar: "Rapid and accurate prediction of protein homo-oligomer symmetry using Seq2Symm" @iscb.bsky.social #ISMBECCB2025

Please welcome to our first Keynote Speaker Dr Franca Fraternali - University College London. #3DSIG #ISMBECCB2025 @iscb.bsky.social #ISCB

#3DSIG in ISMB/ECCB 2025 have started!
We see in the ROOM 03B. We are very excited to welcome you.
#ISMBECCB2025 #ISCB @iscb.bsky.social

We’re thrilled to have you as Chair of our track, Gonza! 🙌 Your leadership and vision are a huge part of what makes this event so exciting. Let’s make #ISMB2025 unforgettable! 💥🧬

🎙️ Don’t miss their insights, inspiration, and impact.

🚀 FINAL CHANCE TO REGISTER:
👉 www.iscb.org/cms_addon/re...

#Bioinformatics #ISMB2025 #ISMB #ISCB 🧪👩‍💻👨‍💻

#CountdownToISMB

🚨 We’re just DAYS AWAY from the start of #ISMB2025 – the world’s biggest bioinformatics event! 🌍🧬

We’re thrilled to remind you of our THREE incredible CHAIRS for #3DSIG track. Three world-class researchers leading the way in science! 💥

#ISMB2025 #Bioinformatics #ISCB #ISMB 🧪👩‍💻👨‍💻

Registration for ISMB2025 : www.iscb.org/ismbeccb2025...
💥 Don’t miss it! @iscb.bsky.social
#ISCB #3DSIG #ISMB #StructuralBiology

🚨 Keynote Alert at #3DSIG track #ISMB2025!
Join us to hear Prof. Adrian Mulholland discuss how molecular simulations are transforming protein design, from predicting function to guiding evolutionary engineering with AI + QM/MM!
@adrianmulholla1.bsky.social @iscb.bsky.social

She’ll present cutting-edge AI and structure-based strategies for antibody design, from chain pairing prediction to beyond-CDR engineering. ⚛️
@gonzaparra.bsky.social
#3DSIG #ISMB2025 #ISCB #ISMB @iscb.bsky.social

Prof. Franca Fraternali - 3DSIG, ISMB2025

Prof. Franca Fraternali will join the #3DSIG track - #ISMB2025 as a keynote speaker, a leader in structural immunology 🔬
🎯 Decoding Immunity: Structural and Dynamical Insights Driving Antibody Innovation
@gonzaparra.bsky.social @iscb.bsky.social #ISMB #ISCB