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Tim Feinstein

@timnfeinstein.bsky.social

Ph.D. ex-academic, self-published author of “A Heuristic Guide To Quantitative Imaging”. Lead, operations and technical sales at Coastal Microscopes.

2,008 Followers  |  1,253 Following  |  2,307 Posts  |  Joined: 04.09.2023  |  2.0027

Latest posts by timnfeinstein.bsky.social on Bluesky

I guess we’re lucky! We haven’t found the hole they use to get into our basement yet, but we can keep ahead of them by leaving out a trap or two whenever droppings say a new guest’s moved in.

22.10.2025 12:59 — 👍 2    🔁 0    💬 1    📌 0

There’s an irony in how the mouse trap was pretty much Pareto optimized with the spring board design in 1898. I’ve tried the alternatives, setting aside awful things like glue strips. If you build a better one the world will beat a path to your door out of sheer surprise.

22.10.2025 00:05 — 👍 1    🔁 0    💬 1    📌 0

Yes that’s what it is! Thanks for giving it a name. You can pinch-zoom and see the reversed colors, with red on the inside instead of violet.

21.10.2025 13:47 — 👍 1    🔁 0    💬 1    📌 0

It’s not a lens effect - daughter and I first saw it while driving. You could actually see the bit-of-rainbow better by eye, or else it faded a bit by the time we found a spot to get out and take a photo.

21.10.2025 13:39 — 👍 0    🔁 0    💬 0    📌 0
A skyline picture of Pittsburgh, looking west near sunset, with wispy clouds and an odd bit of rainbow in the center left of the image.

A skyline picture of Pittsburgh, looking west near sunset, with wispy clouds and an odd bit of rainbow in the center left of the image.

I saw this weird atmospheric phenomenon in Pittsburgh the other day. Rainbows usually happen opposite the sun, making a ring about 40 degrees around where your shadow. But here the sun’s just out of frame to the left, and you see this persistent rainbow bit just next to it. Any ideas?

21.10.2025 13:35 — 👍 1    🔁 0    💬 2    📌 0

Talking atmosphere layers with my 12yo yesterday, I tried to explain why a space elevator would have q bad day. Inspired by explaining what the ionosphere is and why they call it that.

21.10.2025 13:23 — 👍 4    🔁 1    💬 0    📌 0
Preview
Scientists invent eye implant that helps blind patients see again Device helps restore vision to people suffering from advanced macular degeneration

'The device helped 81 per cent of trial participants suffering from advanced age-related macular degeneration (AMD) to achieve clinically meaningful improvements in their vision, according to research published in the New England Journal of Medicine on Monday.'
www.ft.com/content/c2e8...

20.10.2025 13:28 — 👍 22    🔁 15    💬 1    📌 0

Whyyy do nuclear proteins always have a second job. One knockout, one phenotype, is that too much to ask?

(did my thesis on MEK-ERK, yes, that is too much to ask)

21.10.2025 11:09 — 👍 0    🔁 0    💬 0    📌 0

You’re overthinking this Al

21.10.2025 01:30 — 👍 10    🔁 0    💬 0    📌 0

The Firedoglake crowd, after the blog that tried hardest to whip up calls against the ACA vote for not being perfect enough. I’d feel stronger about it, but a few more negative calls had zero affect either the flood that Bill O’Reilly was already motivating. Positive calls, those got real traction.

20.10.2025 22:11 — 👍 4    🔁 0    💬 0    📌 0

The column where Friedman throws up the white flag to a blogger called Atrios (@eschatonblog.com ) is called “No More Friedman Units”. Tom fancies himself the leading foreign policy columnist on *the* foreign policy newspaper; you can imagine Pinch’s ego took it hard.

20.10.2025 10:55 — 👍 0    🔁 0    💬 0    📌 0

Sulzberger (senior) went all in on hoo-rah America after 9/11, at the expense of reporting standards (you could track it by what happened to ombuds, then “public editor”, etc). Judith Miller, and then Friedman getting pantsed by a liberal blogger, broke him. Holy jihad on “the left” ever since.

20.10.2025 10:29 — 👍 1    🔁 0    💬 1    📌 0

Excel > Prism is a really excellent and flexible solution for raw data to analytical stats to presentation. I love the ratio of cognitive load to output power it gives you. R based solutions trade a higher ceiling and excellent price ($0!) for a steeper learning curve /cognitive load.

19.10.2025 17:21 — 👍 1    🔁 0    💬 0    📌 0

In the Michel Foucault panopticon sense, yes.

19.10.2025 14:58 — 👍 1    🔁 0    💬 0    📌 0

We all remember the Iraq war protests, right? Some people have memories of Reagan era protests. Vietnam (fewer). It’s how they respond to criticism. Always has, always will.

19.10.2025 13:22 — 👍 0    🔁 0    💬 0    📌 0

I’m sure the insurer will be thrilled to pay for a harvest that no one was going to buy.

17.10.2025 20:13 — 👍 0    🔁 0    💬 0    📌 0

And tallest, apparently

17.10.2025 13:47 — 👍 0    🔁 0    💬 0    📌 0

Been there! Glad to hear that you caught it.

17.10.2025 13:44 — 👍 0    🔁 0    💬 0    📌 0

If tactics wins battles and logistics win wars, then Bayard Rustin should be remembered like Eisenhower.

17.10.2025 13:21 — 👍 0    🔁 0    💬 0    📌 0

That also describes the experience of the crew on set

17.10.2025 11:48 — 👍 0    🔁 0    💬 1    📌 0

Titanic, YES. It was literally the whole point of the movie. So he could fund diving on the wreck. Everything else, softer yes. He makes money like some Greek mythical character whose defining trait is ticket profits, and his outlet for all that money is cool subs.

17.10.2025 11:44 — 👍 4    🔁 0    💬 0    📌 0

If I ever stop getting that unique thrill over a science story that starts this way, feel free to bury me.

17.10.2025 11:23 — 👍 3    🔁 0    💬 0    📌 0

These underpants gnome investors are more bearable when we don’t have the underpants shoved down our you know whats all bloody day long

17.10.2025 09:04 — 👍 1    🔁 0    💬 0    📌 0

In short:
What began as a confusing cleavage artifact became a strategy for programmable import of synthetic building blocks and efficient GCE.
It’s a whole new layer of control over ncAA encoding.
Curiosity turned a failed experiment into a new principle! Very proud of the whole team’s work 🙌 9/9

16.10.2025 14:06 — 👍 12    🔁 2    💬 0    📌 0

Whoa! The triple teaching head on the upright Zeiss (judging by color). It’s just missing little lego XKCD cartoons pinned up in the student cubicles.

17.10.2025 06:42 — 👍 3    🔁 0    💬 0    📌 0

I could think of natural history reasons for that, but also pigeons are basically bricks with legs.

17.10.2025 06:23 — 👍 1    🔁 0    💬 0    📌 0

Most teaching about the success of civil rights era protest actions is quite superficial, glossing over the intense discipline, workshopping, coalition building, and strategy prep that went into any of those events. It’s as if showing the background work would harm their authenticity.

17.10.2025 06:08 — 👍 59    🔁 9    💬 2    📌 0

Yeah, that’s an uphill battle. We used the first generation of spinning disks to study Golgi fragmentation-reassembly during mitosis back in ‘05-ish. Without active focus control, it was a real adventure! Cytokinesis was off the menu until much later. Congrats on capturing it!

15.10.2025 11:05 — 👍 1    🔁 0    💬 0    📌 0

Seeing it cytokinesis proceed to separation, live, is the ultimate test of a scope system! Even after I pass every other check for phototoxicity, cells still collapse at that stage to bi-nucleate if I use any more than the bare minimum of photons.

14.10.2025 15:46 — 👍 3    🔁 0    💬 2    📌 0
Post image

We hire!
The CytoMorpho Lab is looking for an engineer with a background in cell and molecular biology to join our team in Paris. This is a 18-month contract position, but we're open to exploring long-term opportunities.
More details here:
cytomorpholab.com/index.php/jo...

14.10.2025 13:50 — 👍 75    🔁 70    💬 0    📌 0

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