Sheโs got form. Got me v drunk on cocktails the night before I examined one of her PhD students.
05.08.2025 16:33 โ ๐ 2 ๐ 0 ๐ฌ 0 ๐ 0
mBio Journal Homepage
mBio covers the enormity of the interconnected microbial world: from symbiosis to pathogenesis, energy acquisition and conversion, climate change, geologic change, food and drug production, and even ...
Delighted to have started my tenure as an editor for mBio journals.asm.org/journal/mbio handling papers on Streptomyces, natural product evolution and biosynthesis, experimental evolution, bacteriophage resistance, Corynebacterium and engineering biology
02.07.2025 11:02 โ ๐ 37 ๐ 5 ๐ฌ 0 ๐ 0
Interesting read on Streptomyces #natprod rapamycin's potential role as treatment for long Covid and ME
๐งซ๐ฆ ๐งช๐๐
29.07.2025 22:23 โ ๐ 20 ๐ 10 ๐ฌ 1 ๐ 0
My photo collage shows a Roman gold body chain from the Hoxne Hoard
Left photo: close up of the jewelled mount at the front of the body chain. It is a roughly oval gold setting for nine gems. The centre oval cell contains a cabochon amethyst surrounded by four almond-shaped garnets (one damaged) which alternate with four empty circular cells still containing some sulphur. These may have contained pearls. The chain terminals are decorated with lion heads.
Top right photo: view of the front of the body chain displayed on a mannequin at the British Museum. The body chain is composed of four chains which are joined to form an upper-body decoration which passes over the shoulders and under the arms of the wearer, crossing at the front and back.
Bottom right photo: view of the back of the body chain which has a clasp with octagonal mount set with a gold coin of Gratian.
Discovered in 1992, the Hoxne Hoard was buried some time after AD407/8 when Roman rule was breaking down in Britain. Made up of gold jewellery, silver tableware and more than 15,000 gold and silver coins.
Fabulous Roman gold body chain with jewelled mount set with amethyst & garnets. Rear clasp set with a gold solidus coin of Gratian (AD 367-83). Late 4th century.
From the Hoxne Hoard which was discovered by a metal detectorist in Suffolk in 1992.
British Museum ๐ท by me
#FindsFriday
#Archaeology
01.08.2025 17:43 โ ๐ 389 ๐ 84 ๐ฌ 7 ๐ 14
A broad-spectrum antibiotic targets multiple-drug-resistant bacteria with dual binding targets and no detectable resistance - Nature Communications
Through a synthetic-bioinformatic natural product approach combined with peptide optimization, a nature inspired antibiotic, paenimicin, was identified from Paenibacillaceae family. Paenimicin feature...
Keep an ๐๏ธ on PAENIMICIN
Novel 11-residue depsi-lipopeptide found in synthetic-bioinformatic screen of Paenibacillaceae
Binds phosphate and hydroxyl groups on lipid A in Gram- bacteria and teichoic acids in Gram+ bacteria โ broad spectrum activity
in vivo efficacy, favorable PK, no nephrotoxicity
01.08.2025 04:41 โ ๐ 54 ๐ 17 ๐ฌ 3 ๐ 2
Nothing more dangerous than stupid people that think theyโre clever ๐คฃ
31.07.2025 18:37 โ ๐ 1 ๐ 0 ๐ฌ 1 ๐ 0
Itโs a shit job but somebodyโs got to do it
31.07.2025 18:36 โ ๐ 1 ๐ 0 ๐ฌ 0 ๐ 0
black and white image of interpol the band with the 200 best albums of the 2000s text on top of them
Sleep tight, grim rite, we have 200 albums from the 2000s you can revisit here: pitchfork.com/features/lis...
๐ท by Wendy Redfern/Redfern
30.07.2025 16:52 โ ๐ 26 ๐ 5 ๐ฌ 1 ๐ 5
Group Leader in Discovery Plant Sciences | John Innes Centre
The John Innes Centre (JIC) seeks a visionary Group Leader to lead research on Discovery Plant Science.
. #Botany2025 My institution (JIC in Norwich, UK) is hiring for a tenure-track Group Leader in Discovery Plant Sciences - see more here:
www.jic.ac.uk/vacancies/gr...
Let me know if you have questions!
28.07.2025 14:37 โ ๐ 25 ๐ 32 ๐ฌ 1 ๐ 1
That's a wrap!
Another fantastic year @latitudefestival.bsky.social with an amazing team @johninnescentre.bsky.social and @uniofeastanglia.bsky.social
Thanks to all the families that took on our #science Escape Bloom!
Until next time...
27.07.2025 18:56 โ ๐ 7 ๐ 6 ๐ฌ 0 ๐ 0
Happy to say this didnโt age well! ๐ด๓ ง๓ ข๓ ฅ๓ ฎ๓ ง๓ ฟ
27.07.2025 18:49 โ ๐ 1 ๐ 0 ๐ฌ 1 ๐ 0
Evidence supporting the first secondary chromosome in actinobacteria as a hallmark of the Embleya genus
Embleya is a genus within the family Streptomycetaceae, a group of actinobacteria with outstanding capacity for production of specialised metabolites and a strikingly complex life cycle. In this work, we sequenced the complete genome of the new species Embleya australiensis MST-11070 and validated the assembly using optical mapping. The genome of E. australiensis MST-11070 consists of a 7.1 Mb linear chromosome and three additional replicons, including a 4.2 Mb linear replicon, EEC1, significantly larger than all previously described secondary replicons from bacteria. EEC1 is typified by its similar composition to the chromosome in terms of GC-content, codon usage and gene functions. It also carries terminal inverted repeats identical to the chromosome. EEC1 is enriched in biosynthetic gene clusters (BGCs), including the only copy of the BGCs for the spore pigment and the surfactant peptide SapB, metabolites essential for the organism's lifecycle. EEC1 contains an origin of replication with at least some chromosomal properties, and its replication is likely to depend on functions provided by chromosomally located genes. Further comparison of Embleya spp. genomes suggests that EEC1-like replicons are conserved across the genus, in contrast to other known large linear extrachromosomal replicons (megaplasmids) in the order. EEC1 is thus a hallmark of the Embleya genus and is central to its evolution within the Streptomycetaceae family. We propose EEC1 as a secondary chromosome, distinct from previously described secondary chromosomes that utilise plasmid-like replication mechanisms (chromids) and the largest secondary replicon reported in bacteria, to date. ### Competing Interest Statement Ernest Lacey is a Founder, Board Member, and the Managing Director of Microbial Screening Technology Pty. Ltd. The authors declare no competing financial interests. Biotechnology and Biological Sciences Research Council, https://ror.org/00cwqg982, BB/P021506/1, BBS/E/J/000PR9790, BB/X01097X/1, BB/M011216/1 Novo Nordisk Foundation, https://ror.org/04txyc737, NNF22OC0078997
Our new preprint is out! EEC1 is a massive 4.2 Mb secondary chromosome from Embleya australiensis. Conserved across Embleya, these are the first replicons of their kind in Actinobacteria and the largest secondary replicons in bacteria identified to-date!
1/6 ๐ฆ ๐งช๐งฌ๐ฌ
www.biorxiv.org/content/10.1...
09.07.2025 11:56 โ ๐ 27 ๐ 12 ๐ฌ 3 ๐ 1
ZiemertLab
The Ziemert lab is interested in the evolution and distribution of bacterial secondary metabolites. These bioactive compounds are especially important in human medicine as the chemical scaffolds are t...
Check out the Ziemert Labโs new YouTube channel
m.youtube.com/@ZiemertLab
Weโve uploaded short tutorial videos on how to use our tools for genome mining and natural product discovery.
Thanks Semih, @martinaadamek.bsky.social @turgutmesut.bsky.social ! #GenomeMining #SecMet #naturalproducts
08.07.2025 20:09 โ ๐ 47 ๐ 25 ๐ฌ 2 ๐ 1
๐ฆ ๐งโโ๏ธFrom bacterial to human immunity.
We report in @science.org the discovery of a human homolog of SIR2 antiphage proteins that participates in the TLR pathway of animal innate immunity.
Co-led wt @enzopoirier.bsky.social by D. Bonhomme and @hugovaysset.bsky.social
www.science.org/doi/10.1126/...
24.07.2025 18:22 โ ๐ 253 ๐ 118 ๐ฌ 9 ๐ 11
Kenyon College - Details - Assistant Professor of Biology (Tenure-Track)
Kenyon is hiring a TT microbiologist! Please share widely. Iโm the search chair & am happy to answer any questions. careers.pageuppeople.com/695/cw/en-us...
25.07.2025 14:18 โ ๐ 22 ๐ 58 ๐ฌ 0 ๐ 1
Weโre pleased to announce two new vacancies for senior roles at our institute:
Group Leader in Discovery Plant Sciences: www.jic.ac.uk/vacancies/gr...
๐๏ธ Closes 25 August
Independent Fellowship in Plant-Associated Microbial Interactions: www.jic.ac.uk/vacancies/in...
๐๏ธ Closes 5 September
17.07.2025 15:56 โ ๐ 42 ๐ 63 ๐ฌ 2 ๐ 3
We are here!
The team have just arrived on site for another fun filled @LatitudeFest.
Come find us in the Kids Area and take on our science themed Escape Room!
@JohnInnesCentre
23.07.2025 13:19 โ ๐ 3 ๐ 2 ๐ฌ 0 ๐ 0
Hassan Salem
Interview with Hassan Salem, who studies beetles and their microbial partners at the
Max Planck Institute for Biology.
Grateful to the folks @CurrentBiology.bsky.social for the fun Q&A!
Come for the beetles, stay for the symbionts โ and forgive the basketball detour ๐ชฒ๐ฆ ๐
www.cell.com/current-biol...
17.07.2025 08:45 โ ๐ 46 ๐ 17 ๐ฌ 1 ๐ 0
Group Leader in Discovery Plant Sciences | John Innes Centre
The John Innes Centre (JIC) seeks a visionary Group Leader to lead research on Discovery Plant Science.
GROUP LEADER VACANCY
JIC is recruiting a Group Leader in Discovery Plant Sciences.
If you think your research would synergise and thrive at JIC, please apply.
www.jic.ac.uk/vacancies/gr...
16.07.2025 10:46 โ ๐ 65 ๐ 89 ๐ฌ 1 ๐ 3
official Bluesky account (check username๐)
Bugs, feature requests, feedback: support@bsky.app
Confess your sins anonymously - will the internet absolve you?
Buy show tickets 2025: https://sites.google.com/view/fesshole
Add confession https://bit.ly/addfess
Buy book https://amzn.to/40ySjVn
Sponsored by hebtro.co, Run @robmanuelyeah.bsky.social
PhD Candidate in the Fineran Lab - studying the type I-D CRISPR-Cas system ๐ฆ ๐ฉ๐ผโ๐ฌ
๐University of Otago, Dunedin, NZ ๐ณ๐ฟ
Medical Laboratory Technologist. Teacher. Microbiology and Immunology Enthusiast. Tottenham Hotspur Supporter.
plant-microbe interaction scientist @inrae-france.bsky.social working in #France #Toulouse, Deputy director of @lipme-toulouse.bsky.social, Candidate director of @tps-institute.bsky.social, born at 329ppm CO2.
Science, sci-comm, books & gymnastics | Project Manager, Centre for Microbial Interactions ๐ฆ | Chemistry PhD | #BiInSci ๐ณ๏ธโ๐ | he/they
๐Norwich, UK
Protein NMR spectroscopy, teaching, and random opinions
PhD candidate investigating genomic epidemiology of SARS-CoV-2 & STEC at the Quadram Institute with @mmbdtp.bsky.social ๐งฌ๐ฆ ๐ฉ๐ปโ๐ป | she/her
Bioinformatics/Nanopore/Metagenomics person at the Earlham Institute. This is my (unofficial) work related account - I do inane non-work stuff elsewhere!
https://www.earlham.ac.uk/leggett-group
Engineer come bio-technologist running core Sequencing at the Quadram, UK.
Copper (and other metal ions) in microbiology. Not a New PI anymore. Like chocolates. Need dogs. Forever dreaming of warm, sunny vacations.
Our Lab works on the role of glycans in the interaction between gut microbes and the host. Itโs the mucus that binds us!
Federation of European Microbiological Societies | https://fems-microbiology.org | Magnifying microbial impact at FEMS MICRO Milan 2025 | femsmicro.org | #FEMS2025 | Follow FEMS Journals: @femsjournals.bsky.social | #FEMSJournals | #microbiology
This is the official UEA account, Norwich UK.
๐ข Bringing you the latest campus news and updates from our world-leading research (REF 2021)
Top 25 in the UK ๐
We're online Monday - Friday, 9am-5pm.
Cancer Bioinformatician, professor in medical bioinformatics and genomics @Norwich Medical School, UEA. Prostate Cancer focus.genomic.social/@danbrewer @danbrewer
https://research-portal.uea.ac.uk/en/persons/daniel-brewer
Bioinformatician, Quadram & Earlham Institute, Norwich, loves when programs break .. not
Cryo-EM โ๏ธ๐ฌ | Molecular machines & mechanisms ๐งฌ | Associate professor @oxfordbiochemistry ghilarovlab.com
Scientist. Host-Microbe Interactions. Airway Microbiome. Multi-omics. Asst. Prof @ UMich. PI of @koziklab VP @ BlackInMicro. Mom. Nerd. Patissier.
https://sites.lsa.umich.edu/koziklab/
Anaerobic Microbiologist | Plant Molecular Biologist | Sustainable Biotech Interest
PhD Candidate
The Kozik Lab @ University of Michigan
