Paresh Jadav

agree, it should be integral to all chronic illnesses research (not just CKD) especially since QOL parameters are easily standardized! And more importantly chronic illnesses are lived and not just measured! #NephJC

HRQOL data were scarce and heterogeneous! so no pooled analysis. Just qualitative data. #NephJC

17 trials with 955 patients
DAPA-CKD had 4,300 CKD patients one of half dozen CKD #Flozin trial

This is so under studied it is pathetic.
If you are going to change someone whole lifestyle you need to bring receipts

Do better dieticians

#NephJC

The only thing more restricted than protein is happiness at dinner- HRQOL #NephJC

“We promised better outcomes not better flavors” #NephJC

Thank you and look forward to the #NephJC event in Houston!

T3a
Chimerism is closer to being mainstream. This trial moves immune tolerance from a "Greek legend" to a reproducible strategy for select pts. The protocol achieved its goal, showing this isn't just single-center "magic." In what other groups would you like to see this protocol used? #NephJC

Woohoo - welcome back Paresh

The whole nephrology world will be descending on your city soon for #KidneyWk

#NephJC

T0c
There have been numerous developments in the field of transplantation that have improved outcomes and success rates. Today 95% of renal transplants are functional after 1 year, and 80% at five years. #NephJC

Hello, #NephJC
this is Paresh from Houston. No COI. Looking forward to the discussion on immune tolerance!

We are thrilled to announce that we have generously received funding for a one-year hypertension fellowship, and we are recruiting now for a candidate to start fellowship July 1, 2026 .
med.stanford.edu/hypertension/e…

-Jehan Zahid Bahrainwala
HTN Fellowship Program Director

“The great phosphate bypass” @hswapnil.medsky.social
#NephJC

Yes.. that would be awesome! Please make it happen. #NephJC

Paresh Jadav, from Houston..no COI
#NephJC

Low Urine Cr concentration: simply very poor clearance in bad AKI. (But not in steady state; as even with GFR of 5 cc/min (72L/day), creatinine excretion remains the same)
Or high water intake.. low urine Cr of 20 mg/dl who is making 4 to 5L of urine a day is having adequate clearance (1000mg)

Ur Na> serum Na
Person taking 150 to 200 meq of Na intake/day (to be in steady state) will have urine Na of 150 to 200 meq/L if they are making 1 liter of urine. (And Urine Na in 130s if 1.5L of urine per day). Number of possibilities with various Na &water intake. Kidney &its precision work!!

Urine studies show -pt is still in AKI &has very poor clearance; so creatinine must still be rising.
In a steady state, at a low GFR, Na reabsorption is often 80s to 90s%. & Urine Na is not uncommonly higher than serum Na.(Based on Na/water intake&not accounting for diuretic that they often require