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Akshaya Jayachandran

@nephromommy-akshu.bsky.social

MD Internal Medicine, PGI Chandigarh DM Nephrology, CMC Vellore, India ๐Ÿ‡ฎ๐Ÿ‡ณ Passionate nephrologist ! ๐Ÿฉบ ๐Ÿ‘ฉ๐Ÿปโ€โš•๏ธ Perspicacious toddler mom ! ๐Ÿ‘ฉ๐Ÿปโ€๐Ÿผ

77 Followers  |  72 Following  |  87 Posts  |  Joined: 28.03.2025  |  2.1924

Latest posts by nephromommy-akshu.bsky.social on Bluesky

Oh, thatโ€™s great to know.
And yes, it makes sense actually.
My patients do love โ€˜naturalโ€™ medicine too.
#NephJC

03.12.2025 02:55 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Novice question - If the placebo ๐ŸŒฝhas health benefits in itself, and fish ๐ŸŸ oil still fared better,
Isnโ€™t it a good thing ?
#NephJC

03.12.2025 02:53 โ€” ๐Ÿ‘ 2    ๐Ÿ” 1    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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T3d
Benefits may vary, and results in the general population on CV risk and mortality are still
controversial.
Overall, the results of recent studies have been mixed results. Different study populations,
end points and dosing may account for the lack of clarity. #NephJC

03.12.2025 02:43 โ€” ๐Ÿ‘ 9    ๐Ÿ” 5    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 1

On the fun side, I donโ€™t think anyone would go to the counter and get Fish oil, more so considering how our ESKD patients โ€œhateโ€ their pill burden !
#NephJC

03.12.2025 02:48 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Yes, a few previous studies also looked at bleeding as one of the outcomes measured. I just came to know about this risk while compiling for the summary.
#NephJC

03.12.2025 02:44 โ€” ๐Ÿ‘ 5    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

No and even when my relatives ask me if they should continue - my replies are usually โ€œMehโ€ ! Iโ€™ve not been very โ€˜evidence-basedโ€™ with my opinions, (now I am - based on ASCEND/ VITAL) and somehow I donโ€™t believe that it does much good - again glad to change my opinions based on evidence. ๐ŸŽ #NephJC

03.12.2025 02:14 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Some fish I found at Taipei Airport yesterday !
Yeah Iโ€™ve been seeing fish everyday after working on the PISCES summary !

Some fish I found at Taipei Airport yesterday ! Yeah Iโ€™ve been seeing fish everyday after working on the PISCES summary !

Hey this is Akshaya, junior faculty from CMC Vellore, India.
Currently joining in from Taiwan ๐Ÿ‡น๐Ÿ‡ผ - here for the APCN !
๐ŸŸ
Honestly, most of my CKD patients are poor and Iโ€™ve been guilty of stopping some of their randomly prescribed fish oil because it costed them a whale!
#NephJC

03.12.2025 02:06 โ€” ๐Ÿ‘ 7    ๐Ÿ” 0    ๐Ÿ’ฌ 4    ๐Ÿ“Œ 0
Preview
PISCES: The Visual Abstract โ€” NephJC Curious how n-3 PUFAs may cut serious cardiovascular events in dialysis? ๐ŸŸ A big signal, a big dose, and a big discussion ahead โ€” donโ€™t miss this #NephJC! Check out the VA made by our master Brian...

Holy Mackerel! ๐ŸŸ
๐ŸฆœAhoy matey! Could fish oil unlock the mysteries of increased CV mortality in ESRD? ๐Ÿดโ€โ˜ ๏ธ #NephJC
Join us for a lively trawling trip 12/2/25 ๐Ÿ›ฅ๏ธat 9pm EST
Check out the PISCES VA by @brianrifkin.bsky.social
www.nephjc.com/news/piscesva

01.12.2025 18:46 โ€” ๐Ÿ‘ 14    ๐Ÿ” 11    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1

A result this shiny usually means you check for scales! ๐ŸŽฃ
Do read and enjoy our #NephJC summary/critical appraisal of the ๐ŸŸPISCES ๐ŸŸ Study (Fish Oil in Dialysis)

www.nephjc.com/news/pisces-...

@nephjc.bsky.social

01.12.2025 19:25 โ€” ๐Ÿ‘ 3    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

The Steroid part was sarcasm ๐Ÿ˜….
But sarcasm didnโ€™t land well ๐Ÿ˜‚.
#NephJC

19.11.2025 02:47 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

I keep up-titrating and maximising RAASi / Flozi for all my IgANs coz thatโ€™s all they can afford, albeit with difficulty (Flozins are still costly by our standards). Steroids are cheap though.

#NephJC

19.11.2025 02:42 โ€” ๐Ÿ‘ 5    ๐Ÿ” 0    ๐Ÿ’ฌ 3    ๐Ÿ“Œ 0

Would they look at outcomes classified by the use of Flozins + RAASi Vs RAASi alone ?

Definitely those who were already on the RAASi/Flozi combo would have better controlled proteinuria ?

#NephJC

19.11.2025 02:39 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0

Welcome Assadu to IgAland ๐Ÿ˜…!
#NephJC

19.11.2025 02:37 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
a man says you 're late in front of trees ALT: a man says you 're late in front of trees

Yeah while the research was already getting over ! #NephJC

19.11.2025 02:30 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
alvin the chipmunk from the alvin and the chipmunks ALT: alvin the chipmunk from the alvin and the chipmunks

These patients seem to be a very docile group compared to all the fiery IgANs we see out here !! #NephJC

19.11.2025 02:28 โ€” ๐Ÿ‘ 4    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Yeah Swapnil I was asking about Sparsenran/ Iptacopan only ! Are they available for use and about their as compared to other standard immunosuppressants.
(Going out of context I think !)
#NephJC

19.11.2025 02:25 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Are any of these FDA approved drugs available commercially and how much do they cost?
#NephJC

19.11.2025 02:18 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Hey Iโ€™m Akshaya, nephrologist working at Vellore, India! I keep reading about the trials and magic drugs for IgAN, see atleast 10 IgANs a week, but when it comes to treatment, weโ€™re still stuck at steroids/MMF, RAASi/Flozins (and a generic version of Budesonide). Long way to go! #NephJC
No COI

19.11.2025 02:06 โ€” ๐Ÿ‘ 6    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
2025 IgAN KDIGO guidelines: fresh out of press, already aging gracefully โ€” NephJC This week, we will discuss the 2025 KDIGO IgAN guidelines. which the shift from supportive care to structured, evidence-based therapy

โฐ 2 hours until chat tonight
#NephJC editorial team debated for a long time...not whether to discuss @kdigo.org IgAN guidelines, but whether to do it after #Kidneywk...Have we said it well: IgAN guidelines: fresh out of press, already aging gracefully?
๐Ÿ‘€See it for yourself

19.11.2025 00:00 โ€” ๐Ÿ‘ 2    ๐Ÿ” 4    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Is it time yet? #NephJC
Its actually beyond my comprehension ๐Ÿ˜…

19.11.2025 01:08 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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TOM of this month goes to ACHIEVE trial (n=2,538), which showed that spironolactone 25 mg daily did not reduce CV events or mortality in dialysis patients, and increased risk of severe hyperkalemia #VA by
@nephromommy-akshu.bsky.social. See the latest #ISNTrialWatch summary for details.

10.11.2025 13:22 โ€” ๐Ÿ‘ 3    ๐Ÿ” 2    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Highlights from my talk yesterday on Alport syndrome spectrum of disorders. (since no one posted it, I'll have to do it myself)

Variants in type IV collagen cause a wide spectrum of disease. #KidneyWk ๐Ÿงต

06.11.2025 18:39 โ€” ๐Ÿ‘ 51    ๐Ÿ” 22    ๐Ÿ’ฌ 3    ๐Ÿ“Œ 1
Preview
Zigakibart Demonstrates Safety and Efficacy in Phase 1/2 Trial | Docwire News Zigakibart showed good tolerability, reduced proteinuria by 60%, and stabilized kidney function in patients with IgA nephropathy (IgAN) over 100 weeks of treatment.

Zigakibart was well tolerated and cut #proteinuria by 60% while stabilizing #kidney function in #IgAN patients over 100 weeks. #nephrology #nephsky #iganephropathy docwirenews.com/post/zigakib...

30.10.2025 18:03 โ€” ๐Ÿ‘ 1    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
2025 IgAN KDIGO guidelines: fresh out of press, already aging gracefully โ€” NephJC This week, we will discuss the 2025 KDIGO IgAN guidelines. which the shift from supportive care to structured, evidence-based therapy

The 2025 @kdigo.org IgAN guideline quietly redraws the map: new drugs, new thresholds, and a sense that the era of โ€œsupportive care onlyโ€ is finally over #Nephsky #Medsky

โœ๏ธSummary by @thekidneywhisperer.bsky.social and
@glomerican.bsky.social

www.nephjc.com/news/igan-kd...

28.10.2025 02:06 โ€” ๐Ÿ‘ 22    ๐Ÿ” 16    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Wonderful ! ๐Ÿ˜‡
A patientโ€™s perspective on IgA Nephropathy !
#NephJC #Nephsky #MedSky

28.10.2025 03:20 โ€” ๐Ÿ‘ 5    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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KDIGO 2025 IgA guidelines - Visual Abstract โ€” NephJC KDIGO 2025 is here. IgAN management is evolving with precision risk tools, new therapies, and a stronger focus on kidney protection. Check out the visual abstract created by Natalia Nombera

โฉ Next #NephJC is on IgA nephropathy @kdigo.org guideline

๐ŸŽจ Nice visual summary by @roxnonna23.bsky.social

www.nephjc.com/news/2025/10...

27.10.2025 17:27 โ€” ๐Ÿ‘ 20    ๐Ÿ” 16    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 2
Preview
a man wearing a hat and a black shirt is standing on a street and laughing . ALT: a man wearing a hat and a black shirt is standing on a street and laughing .

Great chat !
#NephJC

15.10.2025 02:50 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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This is one of the most commonly used protein powders in India - we can see that 100ml has ONLY 8g of protein which can easily be got from a couple of egg whites or even a cup of curd/yoghurt. Yet most of our patients are prescribed these Hi-Fi supplements which drain their pockets. #NephJC

15.10.2025 01:48 โ€” ๐Ÿ‘ 8    ๐Ÿ” 1    ๐Ÿ’ฌ 3    ๐Ÿ“Œ 0

Our patients who canโ€™t afford 3 meals a day are started on โ€œNefroSaveโ€ - even at CKD Stage 3 - sometimes even patients of AKI are on these supplements!
#NephJC

Itโ€™s hard to convince them especially coz we are young nephrologists who are seen as students/nurses ๐Ÿ˜… !

15.10.2025 01:45 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0
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This is a screenshot from an article in the Indian Journal of Nephrology which I liked ! pmc.ncbi.nlm.nih.gov/articles/PMC...

VLPDs need Ketoanalog supplements and are basically impractical and also harmful IMO.
#NephJC

15.10.2025 01:41 โ€” ๐Ÿ‘ 6    ๐Ÿ” 1    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

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