Paola A. Marignani's Avatar

Paola A. Marignani

@pmarignani.bsky.social

Scientist & Professor. DalhousieU MarignaniLab.com Precision Oncology/Model Systems/Signal Transduction/Single Cell Transcriptomics/Informatics/sometimes athlete. Creative Destruction Lab (CDL) Scientist/Business Strategist ORCID: 0000-0001-8070-905X

904 Followers  |  237 Following  |  154 Posts  |  Joined: 05.10.2023  |  1.6457

Latest posts by pmarignani.bsky.social on Bluesky

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ATR promotes mTORC1 activity via de novo cholesterol synthesis | EMBO reports imageimageATR activates mTORC1 by increasing phosphorylation and expression of the de novo cholesterol synthesis enzyme lanosterol synthase in cancer cells. While ATM activates mTORC1 via TSC1/2, ATRโ€™...

โ˜€๏ธโ˜•๐Ÿ‘ฉ๐Ÿปโ€๐Ÿ’ป ATR promotes mTORC1 activity via de novo cholesterol synthesis | EMBO reports www.embopress.org/doi/full/10....

24.07.2025 08:12 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Francesco Bellini Obituary - Montreal, QC Celebrate the life of Francesco Bellini, leave a kind word or memory and get funeral service information care of Centre funรฉraire Cรดte-des-Neiges.

Condoglianze. Un pioniere e visionario Dr. Francesco Bellini. Figlio di Ascoli Piceno, si รจ ritrovato in ๐Ÿ‡จ๐Ÿ‡ฆ dove ha conseguito il PhD. Per il suo importante contributo nel campo della ricerca e dell'economia, Lui ha ricevette il titolo di "Cavaliere del Lavoro"
www.dignitymemorial.com/obituaries/m...

15.07.2025 18:52 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Super cool when a friend is meandering through Santa Croce, #Firenze #Florence and comes across a very distant family tomb from early Renaissance 1348.
#DNAdontlie #LaFamiglia

26.06.2025 16:10 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Canadian Women in STEM @CDNWomenSTEM Our overarching goal is to contribute to the design and development of a national strategy for equity, diversity and inclusion in Canada. Our network is representative of female and women Canadian sci...

Good time to join us at Canadian Women in STEM.

๐Ÿ’กDid you know that Women are significantly underrepresented in senior academic and leadership positions, such as department chairs, deans, and presidents.

Let's be the change makers. #LeadByLifting

docs.google.com/forms/d/17U2...

18.06.2025 11:05 โ€” ๐Ÿ‘ 2    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Canadian Women in STEM - Job Board

Canadian Women in STEM has you covered for job opportunities. If you are looking to transition from post doc to academia or industry, or if you are looking to relocate your research lab, canadianwomeninstem.org/job-board/

Good luck !

17.06.2025 17:17 โ€” ๐Ÿ‘ 1    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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How a discovery in Yellowstone National Park led to the development of PCR - Richmond Scientific A discovery in Yellowstone National Park led to the development of PCR, the gold-standard COVID-19 tests used to fight the global pandemic.

๐ŸŒ”๐Ÿ‘ฉ๐Ÿปโ€๐Ÿ’ป
Just a reminder why it is important to fund basic research.

www.richmondscientific.com/how-a-discov...

09.06.2025 02:42 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
SevenBays, Halifax

SevenBays, Halifax

Friday morning stretch.

Post CIHR panel service. Good luck to all applicants.

06.06.2025 11:19 โ€” ๐Ÿ‘ 5    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Today we celebrate ๐Ÿ‡ฎ๐Ÿ‡น.
La prima celebrazione della Festa della Repubblica Italiana avvenne il 2 giugno 1947, mentre nel 1948 si svolse la prima parata militare in via dei Fori Imperiali a Roma; il 2 giugno fu dichiarato per la prima volta festa nazionale nel 1949. #FestaDellaRepubblicaItaliana

02.06.2025 12:54 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Are you an endocrinologist (PhD or MD) that specializes in hormone-associated cancers in women ?

Interested in joining a research project? DM me.

13.05.2025 18:23 โ€” ๐Ÿ‘ 0    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

To all the mothers, and aunts that mother, Happy Mother's Day ๐ŸŽ‰๐Ÿ’๐Ÿ’•

11.05.2025 20:22 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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After months of designing and making demos, just built a better mouse house that is stainless steel inert, reusable and safe for ๐Ÿญ.

Which housing would you prefer? The red house or the stainless steel custom design housing?
#ScienceIsFun #SafeHousing #MouseHouse

06.05.2025 23:38 โ€” ๐Ÿ‘ 3    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

2/2 Come Canadesi, non dimentichiamo l'importanza della democrazia e del diritto e del privilegio di votare. Goditi questo bellissimo fine settimana e esci e vota lunedรฌ!!
๐Ÿ‡ฎ๐Ÿ‡น๐Ÿ‡จ๐Ÿ‡ฆ

25.04.2025 19:27 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

1/2

Il 25 aprile si celebra una delle festivitร  piรน importanti del calendario italiano, in cui la nazione si riunisce per celebrare l'anniversario della sua liberazione dal fascismo, avvenuta il 25 aprile 1945. Quest'anno รจ particolarmente speciale, in quanto rappresenta l'80ยฐ anniversario.๐Ÿ‡จ๐Ÿ‡ฆ๐Ÿ‡ฎ๐Ÿ‡น

25.04.2025 19:27 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
CAUT advises academics against non-essential travel to the U.S. Given the rapidly evolving political landscape in the United States and reports of individuals encou

๐ŸŒžโ˜•๐Ÿ‘ฉ๐Ÿปโ€๐Ÿ’ปNot my usual posting, but worth the read.
www.caut.ca/latest/2025/...

20.04.2025 10:59 โ€” ๐Ÿ‘ 5    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Cell counts and plating dilutions. Tissue Culture 101.

Good times were had by all.

12.04.2025 15:14 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Always fun to teach new trainees the basics. Just find me a surface to write on and need to remember to use erasable markers ๐Ÿ˜ณ๐Ÿ˜ฌ #ScienceIsFun

12.04.2025 14:59 โ€” ๐Ÿ‘ 4    ๐Ÿ” 0    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0
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A lupus-derived autoantibody that binds to intracellular RNA activates cGAS-mediated tumor immunity and can deliver RNA into cells Delivery of autoimmune diseaseโ€“associated antibodies activates the immune system to fight glioblastomas.

๐ŸŒžโ˜•๐Ÿ‘ฉ๐Ÿปโ€๐Ÿ’ป
www.science.org/doi/10.1126/...

11.04.2025 12:23 โ€” ๐Ÿ‘ 0    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Insightful comments from @pmarignani.bsky.social about opportunities and relation to the research funding ecosystem in Canada.๐Ÿ

10.04.2025 01:17 โ€” ๐Ÿ‘ 1    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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While other parts of Canada see forsythia blooms and prepare for vegetable gardens.....just another sunny day in Nova Scotia.

Got to love the climate diversity of Canada.

09.04.2025 13:48 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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.....and this is why I leave winter tires on until May. #HalifaxWinter #SpringSnow

08.04.2025 14:42 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Forward thinking initiative @uhnresearch.bsky.social. Laying foundation 4 ๐Ÿ‡จ๐Ÿ‡ฆ to lead in scientific discoveries & innovations that will improve health outcomes. UHN launches breakthrough solutions that support research from early-stage career scientist 2 patient care.๐Ÿงซ๐Ÿงช๐Ÿ”ฌ๐Ÿงฌ

ctvnews.ca/health/article

07.04.2025 22:19 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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AI is transforming university teaching, but are we ready for it? - University Affairs University instructors, leaders, and staff should all be involved in the AI discussion

AI is transforming university teaching, but are we ready for it? University instructors and staff should be involved in the AI discussion, as should highschool& gradeschool teachers. The learning transformation starts a decade + before students enter University.

universityaffairs.ca/opinion/ai-i...

05.04.2025 11:15 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Back in training mode. Indoor climbing gyms are a great way to build strength, confidence and explore new climbing strategies.

Two years in the making. But before I start, โ˜• needed.

04.04.2025 11:41 โ€” ๐Ÿ‘ 6    ๐Ÿ” 1    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
This is Epigenetics: A CEEHRC Podcast | This is Epigenetics Welcome to This is Epigenetics!โ€”a bilingual podcast, producedย by the CEEHRC trainee committee, where we interview renowned Canadian scientists about their career, their research and, more importantly,...

๐ŸŽ™๏ธ New episode! Dr. Paola Marignani (@pmarignani.bsky.social) founder of Canadian Women in STEM, shares her journey into cancer epigenetics & why a fulfilling career doesnโ€™t need a traditional pathโ€”just one that sparks joy!โœจ
๐Ÿ”— shorturl.at/2bQvl
@dalhousieu.bsky.social
#WomenInSTEM #Epigenetics

02.04.2025 20:05 โ€” ๐Ÿ‘ 8    ๐Ÿ” 4    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Eye of Horus monitoring cell division. #ScienceIsFun

01.04.2025 19:31 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Thanks Prime Minister Carney @mark-carney.bsky.social for visiting Windsor !

Great pic of you and my brother Angelo!๐Ÿ‡จ๐Ÿ‡ฆ

26.03.2025 21:30 โ€” ๐Ÿ‘ 4    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Maple Leaf synonymous with Canada.

Maple Leaf synonymous with Canada.

Maple Leaf synonymous with Canada ๐Ÿ‡จ๐Ÿ‡ฆ.

La feuille dโ€™รฉrable est synonyme du Canada๐Ÿ‡จ๐Ÿ‡ฆ.

23.03.2025 11:57 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Minerals and resources map of Canada.

Minerals and resources map of Canada.

๐Ÿค”Looks like a Periodic Chart to me.

18.03.2025 02:19 โ€” ๐Ÿ‘ 2    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1

Interested in studying cancer metabolism, recurrence & translational application of machine learning 4 biomarker discovery? NSERC has new programs. Got a MSc, apply for PhD positions in the Marignani Lab, Sept 2025 admissions. www.nserc-crsng.gc.ca/NewsDetail-D...

16.03.2025 00:34 โ€” ๐Ÿ‘ 3    ๐Ÿ” 4    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Spectacular ๐Ÿคฉ

14.03.2025 09:22 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

@pmarignani is following 19 prominent accounts