Kathleen_L_Keller

Lab lunch to say goodbye to our French student Carla!

Semaglutide drives weight loss through cAMP-dependent mechanisms in GLP1R-expressing hindbrain neurons Glucagon-like peptide 1 receptor (GLP1R) agonists like semaglutide drive weight loss through the brain, but insights into their intracellular signaling mechanisms are lacking. Although canonically GLP...

Check out this cool preprint from the Krashes and Lutas labs on the signaling mechanisms of semaglutide GLP-1R agonism in the dorsal vagal complex:

www.biorxiv.org/content/10.1...

The 2024 SSIB Special Edition of Physiology and Behavior is now available! Check it out: www.sciencedirect.com/special-issu...

Over the next few days we will be highlighting articles from this issue. Let us know which one you want to see covered first.

Energy Homeostasis in Depression Pathophysiology and Heterogeneity This study examines whether the genetic liability of metabolic, interoceptive, and motivational pathways involved in energy homeostasis regulation is associated with specific symptoms of major depress...

Does altered energy homeostasis contribute to distinct symptom profiles in depression? A polygenic score capturing the genetic liability of the homeostatic system shows promising associations with symptoms.
Great work by @ymilaneschi.bsky.social +team #neuroskyence 🩺
jamanetwork.com/journals/jam...

The amazing Wolfgang Langhans took this of me at the #SSIB2025 nerd prom, and I couldn’t love it more!

Thanks so much for all you’ve done over the past year! #SSIB2025 was an outstanding meeting with great science and networking!

#SSIB2025 let’s rock this thing. I’ll see you on the dance floor in Philly and look forward to the most amazing eating behavior science!

Fabulous Mars lecture by Marion Hetherington @ssibsociety.bsky.social @ssib2025

Hope to see you next year in Philly!

Whooot whooot!!! Amazing talks at!

Absolutely! Hope to see you again soon. #ssib2025

And honestly I’m not sure any candidate will ever win who completely denounces Israel. That is unrealistic

This “all or nothing” attitude will lose more elections for Dems. We are more than a single issue (regardless of how important that issue is)

Purity tests got us round 2 of Trump.

Grrr! Awful

Ugh! I’m so sorry. This truly sucks,

The Nutritionist Marion Nestle Meets Her Moment, At 88 After five decades in the field of nutrition, Dr. Marion Nestle thought she had seen it all. Then came “Make America Healthy Again.”

www.nytimes.com/2025/04/07/w... was such an honor to spend a bit of time with Dr. Nestle on her trip to Penn State

Honored to receive the @pennstateuniv.bsky.social Nutrition and Dietetics Outstanding Alumni Award. I got my own Nittany Lion! It was a great short trip and I got to see some of my favorite people, including @katkellerlab.bsky.social #WeAre Also, TSA was not a fan of my Nittany Lion Statue 😂

Looking forward to voting you out!

Study section today and they announced diversity fellowships are being reinstated!!!

Same. It’s so hard to figure out how to provide leadership right now

We were told by our SRO that it was down for maintenance this weekend

Yes it would be a new submission. I’m so sorry this is so stressful.

These are fellow ship proposals submitted under diversity mechanisms. Strong scientific proposals. NIH makes it impossible to shift mechanisms without a complete new submission

On study section to review NIH fellowships next week and got a message yesterday that diversity submissions under PA-23-271 were being withdrawn. Feel so terrible for these trainees

Absolutely not. Just the topping on my anxiety sundae for today

Call it by its name: A coup. February 1, 2025

It’s a coup! Please read or listen to Robert Hubbell’s newsletter!
open.substack.com/pub/roberthu...

This platform is turning into a pretty nice place! I appreciate the community now

Lab holiday happy hour! Cheers!