Miha Kosmac

What Rosalind Franklin truly contributed to the discovery of DNA’s structure Franklin was no victim in how the DNA double helix was solved. An overlooked letter and an unpublished news article, both written in 1953, reveal that she was an equal player.

On the event of James Watson's death, I highly recommend this 2023 commentary from @matthewcobb.bsky.social and Nathaniel Comfort with crucial new insights into the discovery of the double helix. (And also check out Cobb's brand new biography of Francis Crick) www.nature.com/articles/d41...

The Empire State Building flanked by two buildings, under a broken cloudy sky.

Sometimes you just gotta look up and marvel about the things that human beings have built together.

The driver "managed to contact the control centre at Network Rail and get the train diverted onto the slow line", Calder says. "That was absolutely crucial because this train was scheduled to be travelling through Huntingdon station on the tracks with no platform at 125mph." "It didn't stop in the middle of nowhere, which would have been very difficult." Calder thinks this was handled in the "safest possible way" thanks to the "incredible professionalism from the driver and the police". Train drivers are trained on how to take appropriate action, he adds,

Next time someone tells you that train drivers "just push buttons" show them this from the BBC

Tchéky Karyo, star of Nikita and The Missing, dies at 72 The French actor was known for supporting roles in films that spanned nearly 40 years.

Oh non !
www.bbc.co.uk/news/article...

Pre-print alert! And this one really is a must read for anyone that does spectral #flowcytometry. It is a complete, fully-automated spectral unmixing pipeline that reduces error up to 9000-fold.

Want to get a tough sample, like lung, looking like this? Read more!

www.biorxiv.org/content/10.1...

I am genuinely impressed by large language models - they can absorb disparate components of text into some consolidated view, they can produce extremely good language and - with the right model - translate pretty well between languages and they are an excellent text based UI for humans to use. But..

Nobel Prize in Physiology or Medicine 2025 The 2025 Nobel Prize in Physiology or Medicine has been awarded jointly to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries ...

Happy #treg day everyone - congratulations to Mary Brunkow, Fred Ramsdell, Shimon Sakaguchi and to all the immunologists who have contributed to this incredible field. See our collection: www.nature.com/collections/...

For our #flowcytometry peeps, would you like to have a single fix/perm protocol that is optimised for everything? One that preserves fluorophores while allowing simultaneous TF and cytokine staining? How about 100-fold cheaper?

You got it:
currentprotocols.onlinelibrary.wiley.com/doi/10.1002/...

Let's be honest: this is so much better (and more memorable) than the real one could ever have been.

One for the ages.

#LaVuelta25

Each other's? Do tell more...

Hypercapitalist hellhole or city of dreams? Behind the cliches, let me show you the real Dubai | Momtaza Mehri Everyone’s got an opinion about the city. But few in the west know the multicultural, unusual Dubai that I’ve seen up close, says poet Momtaza Mehri

Hypercapitalist hellhole or city of dreams? Behind the cliches, let me show you the real Dubai | Momtaza Mehri

Monoclonal antibodies were invented at the institution I did my PhD - MRC Laboratory of Molecular Biology in Cambridge.

A funny backstory to this is that Milstein tried to patent the finding, however, the MRC concluded that they were unable to "identify any immediate applications"..

Oopsie 🤦‍♂️

Wait, is that Bashar al-Assad???

Someone asked if I had plans for the fall.

It took me a moment to realize they meant "autumn," not the collapse of civilization.

Fifty years of monoclonals: the past, present and future of antibody therapeutics - Nature Reviews Immunology Fifty years ago, Köhler and Milstein introduced the world to hybridoma technology for the generation of monoclonal antibodies. Scientists have subsequently built upon this seminal discovery to develop...

Review @natrevimmunol.nature.com
Fifty years of monoclonals: the past, present and future of antibody therapeutics
www.nature.com/articles/s41...

A C. elegans model for a human disease

This is figure 2 showing how SNAP-tag engineering is aiming for faster and brighter fluorescence labeling

SNAP-tag is a widespread tool for labelling protein for bioimaging. An article published in Nature Chemical Biology presents SNAP-tag2 with increased labelling kinetics and brightness, which translates into a better performance in live-cell super-resolution imaging. go.nature.com/46fMIZd 🧪

I'm excited about a new @biorxivpreprint.bsky.social story that just went live! This one takes a #computational #immunology approach to understanding #tissueresident lymphocytes. The story highlights the extra value mathematical modelling can bring to biology. 🧵1/10

www.biorxiv.org/content/10.1...

Mosquito-borne viral disease sweeping Indian Ocean islands Safety issues with the only available vaccine complicates response to chikungunya

Mosquito-borne chikungunya disease sweeping Indian Ocean islands @meredithwadman.bsky.social @science.org
www.science.org/content/arti...

This post needs but a minor update.

Listened to it today and absolutely loved the interview. I thought he also handled Alastair's somewhat poorly timed question about the loss of his son very well and even found a way to put a positive spin on it, which takes character. Really recommend a listen.

Take a look at this feature with our faculty member Prof Sergio Quezada, discussing research into how Treg depletion in brain tumours enhances antitumour responses #ImmunoSky

Which Arm Gets Vaccinated Could Matter More Than You Think Scientists have found that receiving a COVID-19 booster shot in the same arm as the initial dose triggers a faster and more effective immune response, thanks to primed macrophages in nearby lymph nodes....

Which Arm Gets Vaccinated Could Matter More Than You Think #Science #HealthandMedicine #PublicHealth #Vaccination #Immunology

Really valuable work and thanks so much for the explainer thread as well!

The Gambler Who Cracked the Horse-Racing Code Bill Benter did the impossible: He wrote an algorithm that couldn’t lose at the track. Close to a billion dollars later, he tells his story for the first time.

This mathematician wrote an algorithm that couldn’t lose at the horse track.

A billion dollars later, he told us his story in 2018

This is the dumbest shit imaginable and will absolutely kill people.

Loved the podcast, really fun. Excellent choice for the 100th episode.

Sure, eggs are expensive but Trump has made stocks affordable for everyone.

The first time I learnt of this unusual Alaskan dogsled race was from a book recommendation by Oded Rechavi. The book is called Impossible Owls by Brian Phillips. The story around this race is the first of several unconnected short stories. Sadly dog deaths are very frequent in this race.

Iditarod officials announce first dog death of this year’s race A dog has died in 37 of the 53 editions of the famous sled dog race, which spans more than 1,000 miles in Alaska.

A 4-year-old female dog died Friday during the Iditarod, the famous long-distance sled dog race. A dog has died in 37 of the 53 editions of the race, which spans more than 1,000 miles in Alaska.