Amanda Smythers's Avatar

Amanda Smythers

@amandalsmythers.bsky.social

PhD, Analytical Chemistry • Postdoc in Spiegelman, Chouchani, & Gygi labs, Dana Farber Cancer Institute & Harvard Med School • #TeamMassSpec #Proteomics #MolecularMetabolism

1,333 Followers  |  1,016 Following  |  147 Posts  |  Joined: 22.09.2023  |  2.3208

Latest posts by amandalsmythers.bsky.social on Bluesky

Same. My kid is at sleep away camp right now and it’s hard to not jump in the car and go get her.

06.07.2025 02:24 — 👍 1    🔁 0    💬 0    📌 0
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Obituary information for Mark Allan White View Mark Allan White's obituary, contribute to their memorial, see their funeral service details, and more.

I’m sad to share that my father died yesterday after a 5 month battle with pancreatic cancer.

It’s a horrific disease. So grateful for my colleagues at the @danafarber.bsky.social for helping me through this process.

www.cunninghamfuneralhome.net/obituaries/M...

29.05.2025 00:21 — 👍 14    🔁 0    💬 8    📌 0
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Don't Miss Out - TOMORROW - it's an interactive proteomics seminar series!

The CNPN x US HUPO Spotlight Series Webinar brings you cutting edge proteomics research from leading Canadian and US scientist.

Register NOW: ow.ly/lSY150VNhpI

26.05.2025 18:28 — 👍 4    🔁 2    💬 0    📌 0

America cannot long remain free, nor first among nations, if it becomes the kind of place where universities are dismantled because they don't align politically with the current head of the government.

23.05.2025 16:00 — 👍 48188    🔁 11374    💬 1474    📌 463
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Rough time in our house as we said goodbye to our cat yesterday. 12 years was not nearly enough.

23.05.2025 14:19 — 👍 10    🔁 0    💬 3    📌 0
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Busy couple of days! Kiddo scored her first goal in Boston, me and the hubs saw Tina Fey and Amy Poehler on tour, and Jewish heritage night at the Sox marked the coldest baseball game of my life 😅 Just a quintessential New England weekend 🤣

21.05.2025 01:22 — 👍 9    🔁 0    💬 0    📌 0
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Northwestern has not received any NIH funds since March. No written communication about why or what can be done. Thank you Ben Singer for raising awareness at #ATS2025

18.05.2025 22:44 — 👍 1476    🔁 608    💬 18    📌 65

This is completely false. Even the largest university endowment cannot sustain large-scale scientific research.

In my 25 years at my school, the most monumental research fund drive raised $325M in *total*. Federal research here costs $200M per *every year*.

This is an extinction-level event.

17.05.2025 14:09 — 👍 1335    🔁 386    💬 35    📌 20

I assume there will be pretty angry QQQ users soon…

13.05.2025 13:36 — 👍 1    🔁 0    💬 1    📌 0
Transcribed text:
Skyline Targeted Mass Spec Environment

Dear Skyline Users,


I would like to thank Agilent, Bruker, Shimadzu, Thermo Fisher, and Waters for their continued funding support for the Skyline project this year.  This industry/government/university partnership allows all of us to maximize the value of our efforts to provide better mass spectrometry tools to the field. In the current federal funding environment, industry support is critical to maintain our work.


Some instrument vendors, such as SCIEX, have not invested in the Skyline project this year. As a public university, we are limited in how we can support the private sector under state law.  We paused our work in Skyline and ProteoWizard on support for SCIEX instruments to remain in compliance with state law. While we hoped SCIEX would resume its funding support of the Skyline project for use with their instruments, and respect their decision not to provide funding, we cannot continue our work to support SCIEX in Skyline or ProteoWizard without SCIEX funding. We have informed the ProteoWizard Foundation of this development.


As always, we look forward to seeing many of you at ASMS or our Skyline course at UW this summer. We thank all of you for your continued support.

Brendan MacLean,

Skyline Project Lead

Transcribed text: Skyline Targeted Mass Spec Environment Dear Skyline Users, I would like to thank Agilent, Bruker, Shimadzu, Thermo Fisher, and Waters for their continued funding support for the Skyline project this year. This industry/government/university partnership allows all of us to maximize the value of our efforts to provide better mass spectrometry tools to the field. In the current federal funding environment, industry support is critical to maintain our work. Some instrument vendors, such as SCIEX, have not invested in the Skyline project this year. As a public university, we are limited in how we can support the private sector under state law. We paused our work in Skyline and ProteoWizard on support for SCIEX instruments to remain in compliance with state law. While we hoped SCIEX would resume its funding support of the Skyline project for use with their instruments, and respect their decision not to provide funding, we cannot continue our work to support SCIEX in Skyline or ProteoWizard without SCIEX funding. We have informed the ProteoWizard Foundation of this development. As always, we look forward to seeing many of you at ASMS or our Skyline course at UW this summer. We thank all of you for your continued support. Brendan MacLean, Skyline Project Lead

Disappointing to see, across both parties.
Sciex is no longer providing funding for Skyline/Proteowizard as part of the multi-vendor agreement to keep Skyline supported across all major vendors.
I can see the arguments from both sides, just a shame it's resulted in this.

13.05.2025 13:34 — 👍 19    🔁 6    💬 6    📌 4
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Lucky 13 in the books today. ✨ Kiddo had a sleepover so we could enjoy this “hidden” cafe in Beacon Hill with enough champagne to give me proper rosy cheeks 🥰🥂

11.05.2025 03:48 — 👍 8    🔁 0    💬 0    📌 0
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Exclusive: NSF faces radical shake-up as officials abolish its 37 divisions Changes seen as a response to presidential directives on what research to fund

Now they are gutting NSF. This is radical destruction.

The Trump goal is to end scientific research in America. Our sense is that few people, even inside the government, have actually grappled with this reality.

09.05.2025 03:22 — 👍 290    🔁 127    💬 9    📌 8

The current administration’s narrative that Harvard (and all universities) feel “entitled” to federal dollars misleads the public. Nor are these funds a “privilege” 1/n

06.05.2025 01:31 — 👍 284    🔁 83    💬 7    📌 2

FWIW, NIH had already silently barred Harvard and four other schools from receiving funds — and agency staff were forbidden from telling applicants and grantees about it.

bsky.app/profile/maxk...

06.05.2025 00:49 — 👍 488    🔁 192    💬 10    📌 8

Existing grants are frozen, too. 😩

06.05.2025 01:18 — 👍 0    🔁 0    💬 1    📌 0
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US HUPO - Job Board

These are truly unprecedented times for science, & I know several community members facing job loses. It would be incredibly helpful for those hiring in proteomics to post to our US HUPO job board so we can help our colleagues find new positions.

Please share!

us-hupo.org/US-HUPO-Job-...

05.05.2025 19:53 — 👍 5    🔁 2    💬 0    📌 0

So excited to see this work!

27.04.2025 23:19 — 👍 3    🔁 0    💬 0    📌 0

Poor kiddo understands the bread of affliction has consequences!! 😅

22.04.2025 16:20 — 👍 0    🔁 0    💬 0    📌 0

My stomach (and heart) is satisfied ♥️

21.04.2025 04:59 — 👍 5    🔁 0    💬 1    📌 0
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Made a reservation at an Italian restaurant to break Passover tonight. I neeeeed noodles. No idea how my kiddo can do stuff like this- I feel like my stomach is full of matzah shaped boulders!

20.04.2025 20:28 — 👍 5    🔁 0    💬 1    📌 1
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SEARLE SCHOLARS PROGRAM NAMES 15 SCIENTISTS AS SEARLE SCHOLARS FOR 2025 Members of the new class of Searle Scholars pursue ground-breaking research in chemistry and the biomedical sciences. Each receives an award of $300,000 in flexible funding to support his, her, or …

I still can't quite believe I am included in the 2025 Searle Scholars cohort. Feeling especially thankful for all who have supported me. I am most excited about the science @riley-research.bsky.social gets to pursue and the support this award provides for my group

searlescholars.org/2025/04/14/s...

18.04.2025 18:51 — 👍 65    🔁 6    💬 3    📌 1

Hearing from sources that grant terminations are starting now, likely targeting grants aimed at broadening participation of underrepresented groups in science.... which congress explicitly asks NSF grants to do.

18.04.2025 20:05 — 👍 42    🔁 28    💬 3    📌 3
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Harvard University Harvard University is devoted to excellence in teaching, learning, and research, and to developing leaders who make a difference globally.

Harvard redid its whole homepage to push back against the administration’s demands. I mean, this is just a website but I think it’s kind of a great PR move: www.harvard.edu

14.04.2025 19:10 — 👍 7023    🔁 1504    💬 113    📌 216

Very glad that Harvard will fight. History is not kind to those who give up their rights freely.

14.04.2025 17:29 — 👍 3    🔁 0    💬 0    📌 0
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I hope everyone celebrating has a wonderful Passover! We are praying for an end to warfare, our hostages to return, and injustice to end- in the US and elsewhere. Grateful to be with family and to enjoy these traditions with my kiddo.

13.04.2025 17:59 — 👍 5    🔁 0    💬 0    📌 0
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Metabolites are not genes — avoiding the misuse of pathway analysis in metabolomics - Nature Metabolism Pathway analysis, originally developed for gene expression data, has been adapted for metabolomics. However, owing to the unique characteristics and constraints of metabolites compared with genes, pat...

www.nature.com/articles/s42...

Metabolites are not genes. repeat, please!

11.04.2025 18:00 — 👍 90    🔁 30    💬 0    📌 1

Feeling fortunate for the opportunity to thank the many mentors who have supported me and to highlight the outstanding scientists in @riley-research.bsky.social. Excited to keeping working together as a group and with the bigger #glycotime and #TeamMassSpec communities to advance glycoscience

08.04.2025 13:01 — 👍 42    🔁 5    💬 4    📌 0

My kid single handedly wipes out at least a half dozen hard boiled (dripped with salt water, of course) over the two nights… an expensive holiday! 🙈

08.04.2025 12:51 — 👍 2    🔁 0    💬 0    📌 0

What the actual fuck

07.04.2025 23:08 — 👍 1    🔁 0    💬 0    📌 0
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Speaker Spotlight: Bruce Spiegelman @spiegelmanlab.bsky.social
Join us @ #AdiposeBiology Conference in Montreal🇨🇦, Aug 19-20, 2025, to hear from this world leading #metabolism expert!

🔗Register before the early bird deadline at: adiposebiology.com

@mcgillgci.bsky.social @danafarber.bsky.social

07.04.2025 16:48 — 👍 12    🔁 7    💬 1    📌 0

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