Carlos Guardia

These are the most challenging times for early-career scientists and engineers.

My team is doing its bit to help by maintaining and even expanding our database of funding opportunities for early-career researchers.

We found 437 of them.

Download it freely here: research.jhu.edu/rdt/funding-...

Establishment of human trophoblast stem cells from term smooth chorion - PubMed Ch-TS cells may serve as a valuable in vitro model for studying trophoblast biology and placenta-mediated pregnancy complications, similar to TS^CT^/blast cells.

Another week, another curated list of pubs in the #PlacentalCellBio @biomednews.bsky.social report:

biomed.news/bims-placeb/...

My personal fav: hTSCs from the term fetal membrane! pubmed.ncbi.nlm.nih.gov/40759063/

Enjoy!

The choice to have another pregnancy or not can be a difficult decision for #preeclampsia #eclampsia #HELLLPsyndrome survivors & their partners & is highly individualized. Speak with your patients during a preconception visit about what another pregnancy could look like for them

The transcription factor NR2F2 positively regulates the development of androgen-producing cells in the testes of fetal mice.
buff.ly/8SBhVjM

10 days left to apply for SDB #SciComm Internship. Deadline: August 15. www.sdbonline.org/science_comm...

Research Group Leader in Chemical/Synthetic Biology at MRC Laboratory of Molecular Biology Start your UK & international job search for academic jobs, research jobs, science jobs and managerial jobs in leading universities and top...

We are looking to recruit a tenure track group leader in the field of Chemical/Synthetic Biology (in the broadest sense) to lead a research program within the Division of Protein & Nucleic Acid Chemistry ( www.jobs.ac.uk/job/DNW809/r... ) at the MRC Laboratory of Molecular Biology (LMB).

A fun reminder that a loss of 60,000 jobs in and around academia is ~50% more than all coal mining jobs in the entire country.

PIEZO1 drives trophoblast fusion and placental development - PubMed PIEZO1, a mechanosensor in endothelial cells, plays a critical role in fetal vascular development during embryogenesis. However, its expression and function in placental trophoblasts remain unexplored...

After another fantastic @ssrepro.bsky.social annual meeting, here you have last week's selected paper in the #PlacentalCellBio @biomednews.bsky.social report:

biomed.news/bims-placeb/...

Highlight from our neighbors at Duke with an interesting role of PIEZO1 in STB formation!

Enjoy!

Odds of winning NIH grants plummet as new funding policy and spending delays bite Funding multiyear grants up front will sharply cut number of investigators receiving awards

"Concerns are rising that President Donald Trump’s administration is finding new ways to shrink the U.S. biomedical research enterprise [right now]"

Great article from @jocelynkaiser.bsky.social at @science.org
🧪

Hope you have time to come by and meet the presenters, learn about autophagy in the placenta and get to know our new lab! Lisa, our lab manager, and I will be around too, so don't forget to hit us up! See you in DC!

And the next day, Poster Session B (Thu 7/31 at 8:30AM) 🤰🏽!

(27) Role of ATG9B in Proper Placenta Development

Mayra has tons of results to show you what ATG9B (the other ATG9!) seems to be doing in the placenta 😱

First stop, Poster Session A (Wed 7/30 at 8:30AM) 🏃🏽‍♀️

(22) Assessing Placental Autophagy in Response to Exercise

Erixberto will tell you about our studies on physical activity and activation of autophagy in the placenta!

If you are coming to @ssrepro.bsky.social 58th Annual Meeting this week, don't forget to come by the posters of our two talented postbacs!

Papers of the week in the #PlacentaCellBio field, thanks to @biomednews.bsky.social

biomed.news/bims-placeb/...

The highlight of the week goes to the latest report from the Charnock-Jones' lab: pubmed.ncbi.nlm.nih.gov/40681537/

Enjoy!

Through @biomednews.bsky.social, I started curating a list of papers in placenta cell biology and related fields! #PlacentaCellBio

biomed.news/bims-placeb/...

I found Myriam Hemberger's latest article to be the highlight of the week: pubmed.ncbi.nlm.nih.gov/40660370/

Enjoy!

II GAVE Workshop organization and attendee information. (A) GAVE logo (left) and II GAVE Workshop logo (right). (B) Members of the organizing committee. (C) In-person assistants. (D) Scheme of the geographical distribution of Argentine attendees (top) and table showing the in-person assistants' locations (bottom). (E) Attendees by career stage and gender. Blue, early-career researchers; yellow, senior researchers; gray, others; line pattern, self-identifying male attendees.

In this Meeting Review article, Gonzalo Germán Guendulain & co showcase the latest workshop of the Argentine Group for Extracellular Vesicles, emphasizing its impact in fostering national and international collaborations. doi.org/10.1242/bio....

"Don't forget! Voting for #ReproBioaArt closes on July 15th! See the beauty of reproductive research! #Reproductive_Health is #Human_Health! Explore breathtaking images from reproductive scientists woobox.com/2poyka . Vote and help us amplify this vital work by liking or reposting!

YouTube video by National Institutes of Health (NIH) Director’s Desk: The Future of Animal Models in Research | NIH’s Dr. Nicole Kleinstreuer

A discussion of the use of animals in research.

www.youtube.com/watch?v=iSvk...

1/n

(Warning: Rant coming)

Frontiers | Secretion of placental peptide hormones: functions and trafficking The placenta is a dynamic endocrine organ that plays a crucial role in fetal development by secreting a diverse array of peptide hormones that regulate mater...

Our new review on placental peptide hormone secretion is out! Our two postbacs, Sadia and Mayra, did an excellent job summarizing a lot of (sometimes) conflincting data!

www.frontiersin.org/journals/end...

I'm extremely proud of our postbacs, Erixberto Olivencia Álvarez and Maira Perez, who did fantastic work at the recent NIH Postbac Poster Day! Mayra won an NIH Outstanding Poster Award and Erix was featured on the NIH IRP blog! Congrats to you both!! 🎉 #NIH #NIEHS

irp.nih.gov/blog/post/20...

Guardia Studies Role of Environmental Stressors on Fetal Development NIH's Dr. Carlos Guardia studies the placenta. He and his team strive to understand the effects of maternal obesity and other environmental stressors on the future health of the baby.

A little glimpse into our lab at NIEHS/NIH! 👋🏽

On a Nature news article reporting that NIH planned to suspend subawards for foreign collaborations: “No, that’s false. There’s going to be a policy on tracking subawards. The NIH and the government should be able to see where the money’s going.” “I’m really uncomfortable with this conversation, because you’re like, actually spreading rumors that you don’t know anything about. … Nature also is spreading rumors. Halt foreign collaborations, that’s not true.” “We’re working on the policy, Jocelyn. You shouldn’t be reporting rumors. I know there’s leaks all over here, but the leaks don’t actually reflect what’s happening. Don’t write about rumors. It actually makes the things that you and I care about worse. Like it spreads panic.” Later that day, NIH released a policy that halted future subawards to foreign scientists and said they will need to apply directly for money under a system still in development.

With NIH director Jayanta Bhattacharya dismissing my reporting as "false" and "spreading rumors" hours before releasing a policy that confirmed said "rumors," I feel compelled to respond.

Here's an inside look into how this story was reported. It was a weird one. 🧵

www.nature.com/articles/d41...

the word alert is in a purple circle ALT: the word alert is in a purple circle

ACTION ITEM-----ACTION ITEM

Implementation of Schedule F

This is what a lot of us have been worried about.

This allows for many civil service positions to replaced with political appointees. This could include NIH institute directors and even POs.

BUT THERE IS A COMMENT PERIOD...

1/n

Job ad is here! Check it out :)

Is liver zonation conserved from mice to humans? And how does fibrosis affect zonation in patients? Now, these questions are answered using scDVP. Some collaborations are meant to be! @carolineweiss.bsky.social@frosenberger.bsky.social @mannlab.bsky.social@mlsb-borgwardt.bsky.social

ESCRT function, evolutionary diversity and mechanism of action The ESCRTs (Endosomal Sorting Complexes Required for Transport) were discovered in 2002 and became one of the most dynamic fields of research in membrane cell biology. ESCRTs are protein complexes fo…

Abstract submissions for short talks are still opened until April 20th for the EMBO Escrt meeting 2025. There are plenty of options for short talks, please apply online at meetings.embo.org/event/25-escrt

NIH PostBac program is open again! And I will be hiring! #JobPostComing

www.training.nih.gov/research-tra...

This new study identifies #CEBPA as a novel gene involved in the pathogenesis of #hypospadias and shows that abnormal expression of V-maf musculoaponeurotic fibrosarcoma oncogene homolog B and CEBPA affects uroepithelial growth via Wnt/β-catenin signaling. #medsky

#OpenAccess: buff.ly/V1c5F0V

1. For the past thirty years I've had the best job in the world.


I've had the opportunity to follow my curiosity; explore the workings of nature and society; mentor students and junior colleagues in the same process; and teach generations of students about it all.

Measles is preventable with just two doses of measles vaccine.

The #measles vaccine has saved an estimated 5 lives every second since 2000.

👉Prevent measles by getting vaccinated with two doses of the measles vaccine.