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Sarah MacNamee

@macnameesarah.bsky.social

in vivo brain imaging superfan Neurotechnology leader, Inscopix, A Bruker Company PhD @ University of Arizona, BA @ Vanderbilt

60 Followers  |  132 Following  |  8 Posts  |  Joined: 06.03.2025  |  1.4518

Latest posts by macnameesarah.bsky.social on Bluesky

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FREE virtual event next week!

We are showcasing groundbreaking research from leading scientists utilizing advanced imaging technologies from Bruker, including Inscopix and Bruker Spatial Biology (formerly NanoString). www.bruker.com/en/news-and-...

Register to join live & get access to recordings

16.04.2025 19:40 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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We are proud to announce the ProView Express Kit:

πŸ§ͺCreate your own virus-coated lenses using your preferred viral constructs

πŸ‘ŸSingle step surgery with reproducible, localized expression across cohorts

🧠 More time to analyze amazing cell yields on IDEAS?! inscopix.github.io/ideas-docs/i...

04.04.2025 14:37 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

More collaboration! Protocol development and testing with Yi Zuo & Sofia Beas, whose labs saw consistently beautiful fields of view in all animals implanted 🀩

04.04.2025 14:37 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Several logistics prevent this. We also think the coating can be improved.

The Inscopix Discovery Lab collaborates with a Stanford team led by Eric A. Appel, resulting in a coating with slower virus release that increases the working time for surgical implantation.

04.04.2025 14:37 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

A tale about academic & industry collaboration, and how it can help you achieve precise expression for in vivo calcium imaging:

It's 2019. Inscopix offers the only commercially available virus-coated GRIN lens. Neuroscientists are intrigued but ask us about using their unique viral construct. Hmm

04.04.2025 14:37 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

😍 The vessel imaging quality is excellent - you wouldn't guess this is in vivo through a GRIN. There is so much to learn about neurovascular coupling, e.g., in disease specific brain areas and circuits, after drug, etc. I'm excited to see where this leads!

25.03.2025 14:52 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Suppl. Video 4. Nucleus accumbens (compressed)

24.03.2025 20:05 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0

Agreed - kudos @thomasbienvenu.bsky.social 😍

24.03.2025 19:38 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

New tool for studying brain vasculature in vivo: deep brain regions (PFC, nucleus accumbens) were visualized using Inscopix GRIN lenses & the versatile nVue dual color miniscope with sampling @ 100Hz (Supp. movie 4&5).

Gorgeous work, @hajimehirase.bsky.social and team!

24.03.2025 19:19 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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New from the lab!! πŸ‘‰πŸΌ authors.elsevier.com/a/1kgT43BtfH... πŸ“ @cellpress.bsky.social We discovered that genetically-defined neuron types in the hippocampus form unique manifolds! Dual color imaging, chemogenetics and topological analysis all at once! With Juan Gallego @juangallego.bsky.social

26.02.2025 16:16 β€” πŸ‘ 90    πŸ” 32    πŸ’¬ 4    πŸ“Œ 3

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