Pearson Lab

Enjoyed my time at the @foxp1foundation.bsky.social meeting in the Netherlands. So great to see lots of exciting #FOXP1 related research and meet so many inspiring parents 🦊🧪

Know any great developmental neurobiologists looking for a post doc position?
Are you looking for an adventure with cerebral organoids in New York City?
We are looking for an enthusiastic new team member!
Feel free to DM or email me 🧪 🧠 🍎
#science #neurodev #neurobiology #neuroscience #devbio

Cryopreservation of Human Cortical Organoids Using Vitrification Cryopreservation at ultra-low temperatures is a valuable tool for preserving cells and tissues used in research. However, few protocols exist for the preservation of brain organoid models. Current met...

Happy to contribute to this methods paper from our collaborators at University of Michigan - it was an exciting day when vitrified cerebral organoids arrived! 🧪 🧠 👩‍🔬
www.biorxiv.org/content/10.1...

Nobel laureate: I owe America my success. Today, its scientific future is in danger | CNN Dr. Ardem Patapoutian says he watches “with deep sadness as the United States’ remarkable scientific enterprise, which took generations of hard work and national investment to build, faces a concerted...

👏🏻👏🏻👏🏻https://www.cnn.com/2025/04/09/health/nobel-laureate-research-funding-patapoutian/index.html

#fluorescencefriday 🧪🧠🧫😍 I ❤️ neural stem cells

Can finally breathe and celebrate that my R01 application has been funded! 🧪🧠🥳 #GLUT1 #neurobiology

Metabolic Atlas of Early Human Cortex Identifies Regulators of Cell Fate Transitions Characterization of cell type emergence during human cortical development, which enables unique human cognition, has focused primarily on anatomical and transcriptional characterizations. Metabolic pr...

Excited to see the latest preprint from the Badhuri lab at UCLA 🧠🧫🧪
www.biorxiv.org/content/10.1...

Always had a strong squad of #womeninSTEM for support and friendship @emmanning.bsky.social @kchinnaiya.bsky.social Pam Ellis, Katherine Jeays-Ward, Marysia Placzek. Inspiring, encouraging and life long mentorship

Happy International Women's Day!
Science is a team sport and I'm so thankful to be part of such a strong squad of #womeninSTEM
@suprajagv.bsky.social @madelineandrews.bsky.social @jennkong.bsky.social @katrinaladams.bsky.social 🧪💪👩‍🔬🦄

Cell-type-specific roles of FOXP1 in the excitatory neuronal lineage during early neocortical murine development Ortiz et al. leverage mice with loss of FOXP1 in their cortical progenitors. Detailed cell-type-specific genomic and epigenetic alterations are described, with key findings in progenitors related to a...

Fab new study on #FOXP1 and its role during cortical development from Gena Konopka and her team 🧪🧠🦊👏

Do you think it’s more in response to this? www.hhs.gov/about/news/2...

Try this 👇 to access era commons, and view the rest of the thread for access solutions to PubMed, etc.

Johns Hopkins sues federal government over NIH funds Johns Hopkins University joined several universities in a lawsuit on Monday evening suing the federal government over NIH funding.

Johns Hopkins officials said the NIH funding cut puts at risk approximately 600 current and ongoing clinical trials at Hopkins, including open clinical trials in cancer, pediatrics and children’s health, heart and vascular studies and the aging brain. www.thebaltimorebanner.com/education/hi...

New cover slide for work in progress talk tomorrow #devbio #neuroscience 🧪🧠🌈

Microscopy image of an organoid on a computer screen

An actual #microscopymonday in action! Beautiful #organoids packed full of neurons #neurobiology #neurodev 😍🧠🧪

We are hiring! Looking for a research technician to join our team, preferably with some wet lab experience but not necessary. We welcome anyone with a willingness to learn! Applications can be submitted through jobs.weill.cornell.edu/job-invite/9...

Have some reading to do! Thanks @trayon.bsky.social for this list!

Super happy to receive an R03 from the NIMH to continue our work on FOXP1 and further our understanding of its role during brain development 🧪🧠🦊

It seems like there are so many journals that will accept reviews from another journal now it might be worth doing that - especially after a year!

So good to be back in LA for this years #AES meeting! And so much exciting science 🧪

Can I be added? 🙋🏻‍♀️🐁🧠

Had such a fun morning at UCLA. It was so nice to see old friends and meet new people and have the opportunity to present our work 🧪🧠

#neurojobs

Sex-specific perturbations of neuronal development caused by mutations in the autism risk gene DDX3X DDX3X is an X-linked RNA helicases that escapes X chromosome inactivation and is expressed at higher levels in female brains. Mutations in DDX3X are associated with intellectual disability (ID) and au...

Some post-holiday reading! 😍 🧪 🧠@derubeislab.bsky.social
www.biorxiv.org/content/10.1...

Looking forward to visiting #UCLA 🐻 and attending #AES2024 next week….and a trip to Disneyland 😍🏰

4-Phenylbutyrate for STXBP1 and SLC6A1. Safety, tolerability, seizure, and EEG outcomes. A case series at 2 centers Introduction Pathogenic mutations in STXBP1 and SLC6A1 can cause developmental delay and epilepsy. 4-phenylbutyrate (4PB), a drug used for urea cycle disorders, rescues dysfunction in pre-clinical mod...

Promising study from Zach Grinspan and colleagues for #STXBP1 patients 🧪
www.medrxiv.org/content/10.1...

Happy Thanksgiving 🦃

🙋🏻‍♀️

A MOUSE ORGANOID PLATFORM FOR MODELING CEREBRAL CORTEX DEVELOPMENT AND CIS-REGULATORY EVOLUTION IN VITRO Natural selection has shaped the gene regulatory networks that orchestrate the development of the neocortex, leading to diverse neocortical structure and function across mammals, but the molecular and...

Happy to share our mouse cortical organoid system, which recapitulates in vivo tempos and cell types. We used it to identify gene expression changes across subspecies during development, which might underlie neuroanatomical differences and affect disease penetrance. www.biorxiv.org/content/10.1...

human neurons grown in vitro

#FluorescenceFriday human excitatory neurons CTIP2 in red MAP2 in green and DAPI in blue