Gord Fishell

I am so excited about this combined analysis of the selective CRHR2 population within the lateral septum and how they control defensive behavior. Dionnet was truly a gifted graduate student. Keep your eyes on this one!

At my last year of attending the McKnight conference. Such an amazing group of scientists. A big shout out to Lauren Orefice who gave an amazing talk this morning!

Here is a chat with Bosilijka Tasic and myself about the enhancer-mediated AAVs that we were both centrally involved in publishing. I truly believe these approaches are fundamentally important for both basic and clinical approaches! braininitiative.nih.gov/news-events/...

The U.S. Lit a Beacon for Science. Under Trump, Scientists Fear It’s Dimming

So I open up the NYtimes and there is my pal @ardemp.bskyverified.social saying that despite funding cuts he is staying in this country that he loves. Keep the faith you all!.... www.nytimes.com/2025/06/03/u...

Wow quite the legends. Not to mention the white asparagus. Enjoy your fragrant pee dude!

Exploring brain circuits, one cell type—or more— at a time This issue of Neuron, with accompanying papers in Cell, Cell Genomics, Cell Reports, and Cell Reports Methods, contains studies describing methods for access to neuronal and non-neuronal cell types wi...

"Exploring brain circuits, one cell type—or more— at a time" www.cell.com/neuron/fullt...

Bosiljka Tasic & @gordfishell.bsky.social ‬
@cp-neuron.bsky.social

Yep, glad people in europe are taking notice. Hey guys, we are having a giant fire sale! Top scientists looking for relocation to the other side of the pond. Sad!

One thousand candidate enhancers tested in vivo in the mouse brain! A massive resource and oh so useful as validation set for genome-wide enhancer prediction methods. Super fun to be involved in one of the papers: ‘the prediction challenge paper’ by Nelson&Niklas et al www.cell.com/cell-genomic...

Here is the collective effort of 12 labs, lead by my own at the Broad to target the range of cortical interneuron subtypes! These tools should be a game changer for all of you using NHP and other less genetically amenable species! Have at it!
urldefense.proofpoint.com/v2/url?u=htt...

Check out the neuroview and all the great articles of new tools to target different cell types with enhancer-mediated AAVs!

Even though it is spring....it seems to have gotten dark lately...."Within the last several days, Harvard University has received letters from most federal agencies indicating that nearly all of HMS’s active, direct federal grants have been terminated."

There you are with my buddy Domingos!!!

You should write Kara directly or maybe just watch for it on Bluesky. For me this is a work in progress but I will post on Bluesky as I get involved.

I will fly to anywhere in the United States on my own dime to talk to people about basic science! I encourage all of you, particularly senior scientists to make this commitment. If you are looking for material ask @karalmarshall.bsky.social She has put together an amazing basic talk!

OK inspired by @karalmarshall.bsky.social I am reaching out to the public where ever I can. Traditionally Republicans have been incredibly supportive of science. We as scientists need to reach out to people across the spectrum to rally their support for basic science!

Ask Kara for this talk! It is an amazing walk through for the general public.mmI am going to give a general talk to the public every time I am traveling through the USA. I have had a wonderful career. It is my students and postdocs I am worried about 🥺. Come help out!

YouTube video by Steve Lawson Kara Marshall PHD-History of Science in America - Trilogy at Tehaleh 04/27/25

Gave a talk at my parents’ retirement community to describe how science is done, and what is at stake. There was a ton of interest, and anyone can do this. Get the word out about how science affects everyone. I’m happy to share slides with anyone who asks- just get in touch! youtu.be/BY_SFgi-Cig

Yes I know....I was hoping you guys would overlook the error!

Given all that is going on consider this quote from Bertram Russell's 1930 book The conquest of Happiness:
“The man who can be interested in the structure of atoms or the way in which a beetle navigates, is likely to get a joy in life which no amount of success in the pursuit of power can give. ”

Heads up: A ton of papers from my group at the Broad, Pittsburgh, Irvine, Caltech, Duke, Berkeley and especially the Allen are on deck for a big consortium publication on new methods to target range of specific neuronal and non-neuronal cells coming out in Neuron and associated journals May 20th!

Nuff said...https://www.harvard.edu/president/news/2025/the-promise-of-american-higher-education/

Ginty told me you independently made the same recommendation!

Color in the lines of your favorite proteins....can't wait to see David Ginty's full chest tattoo of a Pacinian corpsule!!!

The time has come for all of America to reflect where they stand on the question of academic freedom...

Harvard University Harvard University is devoted to excellence in teaching, learning, and research, and to developing leaders who make a difference globally.

Take a look at the harvard web site...We have our break-throughs and next generation drugs on full display! Come take a look at the new wonders of medicine! So proud to be a part of it!!! Harvard.edu

Harvard has set an example for other higher-ed institutions - rejecting an unlawful and ham-handed attempt to stifle academic freedom, while taking steps to make sure students can benefit from an environment of intellectual inquiry, rigorous debate and mutual respect. Let’s hope others follow suit.

And so the fight begins in earnest!

As Sun Tzu said "Do not press a desperate enemy too hard. Leave him a way of escape." After what happened to Columbia, it's pretty clear capitulation is not a viable option.

Harvard takes a stand, although after Columbia it is not clear what other choice they had.