Modernising Medical Microbiology

Description Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...

📢Job Alert! Translational Research Collaboration Manager in Infectious Disease and Antimicrobial resistance. 🦠💊 Know anyone who would be good? Pass it on! www.imperial.ac.uk/jobs/search-...

Our team wore blue for World Antimicrobial Awareness Week 2025💙

Research into how resistance emerges, spreads and can be prevented is vital. Our group works to understand these processes and develop better tools to detect, monitor and combat antimicrobial resistance.

#WAAW @oxfordbrc.bsky.social

Modernising Medical Microbiology and Big Infection Diagnostics | NIHR Oxford Biomedical Research Centre

This World Antimicrobial Resistance Awareness Week #WAAW, we’re championing our microbiology and infection researchers whose work is benefiting patients and informing health care policy. Read: oxfordbrc.nihr.ac.uk/research-the...

@ox.ac.uk @ouhospitals.bsky.social @modmedmicro.bsky.social

An infographic stating that between now and 2050, 39.1 million people globally will die from infections attributed to antimicrobial resistance. This number is equivalent to over half the current UK population.

An infographic stating that taking your full course of antibiotics can help reduce antimicrobial resistance and save lives.

Why is antimicrobial awareness important?

Antimicrobial resistant infections are rising. In the next 25 years an estimated 39.1 million people globally will die from infections with antimicrobial resistance.

So what can you do to help? Something as simple as finishing your course of antibiotics!

These subpopulations also reveal whether resistance arose before or after infection. Our findings show why even small resistant groups matter—and how choosing the wrong antibiotic can help them take over. 💥

#TB #AMR #WAAW #WAAW2025 #AntibioticResistance @oxfordbrc.bsky.social

In our study, we investigated how often such resistant minority populations occur in clinical TB samples, focusing on rifampicin (RIF). Including these minorities in resistance profiles significantly improved detection sensitivity. 🧪🔍

Resistance testing often yields a single profile per infection. If most bacteria appear susceptible, the antibiotic is used. But this approach fails when a minority, even as little as 5%, are resistant. Those few can survive treatment and take over the infection. ⚔️

Subpopulations in clinical samples of M. tuberculosis can give rise to rifampicin resistance and shed light on how resistance is acquired AbstractObjectives. WGS has become a key tool for diagnosing Mycobacterium tuberculosis infections, but discrepancies between genotypic and phenotypic drug

For #WorldAntimicrobialAwarenessWeek, we introduce our recent paper on antibiotic-resistant subpopulations in TB.
TB may be one of humanity’s oldest diseases, yet it still kills over 1M people yearly. As resistance spreads, knowing each patient’s resistance profile before treatment is vital. 🧬💊

Antimicrobial resistance occurs when bacteria, viruses, fungi & parasites change over time - leading to medicines being less effective against them.
Here you see bacteria growing and antibiotics (the small discs) which kill the bacteria...unless they are resistant!
#WAAW #AMR @oxfordbrc.bsky.social

Bash The Bug (@BashTheBug) / X Bash The Bug (@BashTheBug) / X

Are you interested in infections, the micro-organisms that cause them and antimicrobial resistance? So are @bashthebug.net and they're looking for new members to join their patient & public group. More info: bashthebug.net/lay-represen... Deadline 27 Nov @ouhospitals.bsky.social @medsci.ox.ac.uk

New paper: What can subpopulations tell us about rifampicin resistance? Last Thursday this work which we'd previously preprinted looking at looking at rifampicin-resistant subpopulations in clinical M. tuberculosis samples was published in JAC-Antimicrobial Resistance. If...

New paper by @vbrunner.bsky.social looking at detecting rifampicin resistant subpopulations in M. tuberculosis infections using genetics and putting a lower limit on the proportion that arose due to secondary infections.

bit.ly/47rwf42

@modmedmicro.bsky.social
@oxfordbrc.bsky.social

🔔🔔Post-doc in microbial genomics with @modmedmicro.bsky.social🧬 - deadline tomorrow! Big genomic and clinical datasets to play with, friendly and very multidisciplinary team!

my.corehr.com/pls/uoxrecru...

Subpopulations in clinical samples of M. tuberculosis can give rise to rifampicin resistance and shed light on how resistance is acquired AbstractObjectives. WGS has become a key tool for diagnosing Mycobacterium tuberculosis infections, but discrepancies between genotypic and phenotypic drug

Our recent paper on rifampicin resistant subpopulations in M. tuberculosis (M. tb) has been published at JAC-antimicrobial resistance.

I am really happy to see this work published just hours before submitting my DPhil thesis! 🔗👇
doi.org/10.1093/jaca...

We have a fully funded PhD studentship available @modmedmicro.bsky.social in Oxford to work on a really cool project looking at population heterogeneity in bloodstream infections www.ndm.ox.ac.uk/study/dphil-... Please spread the word/get in touch if you'd like to chat.

Now published in @natcomms.nature.com 🎉

www.nature.com/articles/s41...

With Gillian Rodger, @nstoesser.bsky.social, @samlipworth.bsky.social, @stat-sarah.bsky.social, and many others!

Photo of the Modernising Medical Microbiology Green Team wearing protective clothing, helmets, and safety goggles at the Ardley Energy Recovery Centre during their field trip to see first hand how Oxfordshire waste is burned, instead of ending up in landfill, to generate electricity.

🧪 ♻️ Want to make lab and computational research more sustainable? Check out our Oxford Climate Society blog post:
oxfordclimatesociety.com/blog/from-pi...
Shout out to Green Team colleagues @modmedmicro.bsky.social for helping! #LEAFAward #GreenDiSC #GreenImpact #SustainableScience

From Pipettes to Pipelines — Oxford Climate Society Dorottya Nagy writes about the experiences from the Modernising Medical Microbiology (MMM) Unit research group on engaging wet lab, computer lab, and office teams on the sustainability agenda.

From Pipettes to Pipelines: Greening a Multidisciplinary Research Lab.

@dotnagy.bsky.social writes about the experiences from the Modernising Medical Microbiology (MMM) research group on engaging wet lab, computer lab, and office teams on the #sustainability agenda.

#GreenLab #SustainableScience

Nanopore long-read only genome assembly of clinical Enterobacterales isolates is complete and accurate Whole bacterial genome sequence reconstruction using Oxford Nanopore Technologies ('Nanopore') long-read only sequencing may offer a lower-cost, higher-throughput alternative for pathogen surveillance...

Great new work from #DotNagy @modmedmicro.bsky.social - she tool 96 clinical isolates from the NEKSUS study and sequenced with both Illumina and Nanopore - question was, can we do away with hybrid sequencing for the rest of the study?
www.biorxiv.org/content/10.1...

Pleased to see this pre-printed, highlighting the completeness/accuracy of @nanoporetech.com long-read genome assembly for clinical Enterobacterales: www.biorxiv.org/content/10.1...

Thanks to colleagues @modmedmicro.bsky.social, @ukhsa.bsky.social, @genewiz.bsky.social and @oxfordbrc.bsky.social!

Come and work with Nicole Stoesser and I in Oxford with the fantastic team @modmedmicro.bsky.social - great opportunity for a postdoc in microbial genomics to do some creative research with great datasets as part of our HPRU.

my.corehr.com/pls/uoxrecru...

Great new opportunity to work with #Liamshaw and @mutantbug.bsky.social as part of our HPRU collaboration (www.expmedndm.ox.ac.uk/research/hpr...) - sinks, phages, wastewater genomes, novel threat detection bit.ly/45Wcv6I - deadline 14th Sept 👀

Linking life expectancy to the bacteria in our gut: A final year undergraduate project My name is Akika Altman-Chandler, and I just graduated from the University of Oxford with a degree in Human Sciences. For my undergraduate dissertation, I worked with Teresa Street at the Modernisi…

Updated blog link -> bashthebug.net/2025/08/28/l...

#Microbiology #Microbiome #HealthyAging #GutHealth #StudentResearch

Linking life expectancy to the bacteria in our gut: A final year undergraduate project My name is Akika Altman-Chandler, and I just graduated from the University of Oxford with a degree in Human Sciences. For my undergraduate dissertation, I worked with Teresa Street at the Modernisi…

'Linking life expectancy to the bacteria in our gut: A final year undergraduate project'.

Akika investigated how the gut microbiome influences longevity, with fieldwork in Nagano, Japan—home to the country’s longest-living population.

Read the blog post here ➡️
bashthebug.net/2025/08/22/l...

More evidence to support best practice "water-safe" care in healthcare facilities is urgently needed. If you're interested please tap into the @hisinfection.bsky.social Wastewater and AMR Special Interest Collaborative (SPARC) - see you there!

The Sinkbug Survey: Antibiotics, AMR, Chemicals and Plumbing In this episode of Infection Control Matters, Martin Kiernan speaks with Dr. Nicole Stoesser about a large-scale, multi-centre study exploring the role of hospital sink infrastructure in antimicrob…

More discussion about the JHI study with @emrsa15.bsky.social in the Infection Control Matters podcast series infectioncontrolmatters.com/2025/04/02/t...

Survey of healthcare-associated sink infrastructure, and sink trap antibiotic residues and biochemistry, in twenty-nine UK hospitals Hospital sinks are linked to healthcare-associated infections. Antibiotics and chemicals in sink traps can select for pathogens and antimicrobial resistance (AMR). Optimizing sink design and usage can...

This builds on the SinkBug group's earlier work in @thejhi.bsky.social www.journalofhospitalinfection.com/article/S019... where we showed that sink infrastructure in hospitals was common, highly varied, and that antibiotics were detected in a third of sink-traps.

New analysis from Kevin Chau @modmedmicro.bsky.social for the SinkBug Consortium (a collaboration with teams across 29 UK hospitals, NITCAR, UKHSA): Pathogen and AMR gene burden in 287 hospital sink-trap metagenomes and factors associated with high burdens.

Wellcome Connecting Science hybrid conference Antimicrobial Resistance – Genomes, Big Data and Emerging Technologies Conference dates: 23–25 March 2026 Location: Hinxton Hall Conference Centre, Wellcome Genome Campus, UK and online Bursary deadline: 01 December 2025 Abstract deadline: 15 December 2025 Registration deadlines: In person: 24 February 2026 | Virtual: 17 March 2026

Participate at our global conference on Antimicrobial Resistance🧬

🗓️ 23-25 March 2026 #AMR2026

Join a community at the vanguard of #AMR genomics, to explore how big data and innovative technologies are driving solutions to tackle this health crisis.

📎Abstracts welcome: bit.ly/3SWzJUm
#MicroSky

Bit over 24 hours left to apply for these two posts to help us develop pipelines to process pathogens..!

Senior Bioinformatic Engineer
bit.ly/4ecl0hF

Senior Biostatistical Researcher
bit.ly/4kRfZxI

Grade 8 or 7, depending on experience
closing date: noon Tues 8 July

Job advert to come and work with me on tuberculosis closes tomorrow (Friday) at noon!

Part of #OxCOD4TB

bit.ly/4ndKOhF

@ndm.ox.ac.uk @modmedmicro.bsky.social
@oxfordbrc.bsky.social