Jack B. Roberts

From mechanism to medicine: The progress and potential of epigenetics in osteoarthritis Osteoarthritis (OA) is a chronic, degenerative disease of the articular joints. The disease presents an enormous clinical and economic burden globally…

A little late to sharing this, but we've recently published a report providing an overview of the research discussed at last year's OA epigenetics workshop in Toronto! A brilliant collaborative effort; read it here: www.sciencedirect.com/science/arti...

Many congratulations to the newly elected chairs @thehopefulscie1.bsky.social , @jackbroberts.bsky.social for GRS Cartilage 2027.. Great to see the GRS is in safe hands..

Investigating the role of collagen glycosylation in joint development and homeostasis using stem cell models of neocartilage at Newcastle University on FindAPhD.com PhD Project - Investigating the role of collagen glycosylation in joint development and homeostasis using stem cell models of neocartilage at Newcastle University, listed on FindAPhD.com

We're advertising a fully-funded BBSRC PhD studentship @newcastleuni.bsky.social to work on understanding the biology of COLGALT2 in cartilage using/developing cool model systems w/ Dr James Henstock at @northumbriauni.bsky.social. Pls reach out if you are interested in applying! bit.ly/3DiqHN9

Functional genomics of human skeletal development and the patterning of height heritability A framework for understanding complex-trait genetic uncovers regulatory networks underpinning human height variability.

1/11 Pleased to see our article by the terrific Dr. Daniel Richard
finally out in January 9th the journal Cell: www.cell.com/cell/fulltex...

MRC DiMeN Doctoral Training Partnership: Investigating the role of COLGALT2 in osteoarthritis using a stem cell model of cartilage health and disease at Newcastle University on FindAPhD.com PhD Project - MRC DiMeN Doctoral Training Partnership: Investigating the role of COLGALT2 in osteoarthritis using a stem cell model of cartilage health and disease at Newcastle University, listed on F...

We are advertising a fully funded PhD project starting September 2025. We’ve been excited for this for a long time- biologically unravelling the results of genetic studies to understand the mechanism of cartilage breakdown conferred by SNPs. Reach out if interested! www.findaphd.com/phds/project...

Well done all!!!

The methylomic landscape of human articular cartilage development contains epigenetic signatures of osteoarthritis risk Emerging evidence supports developmental factors impacting osteoarthritis risk in older age. Here, we quantify the methylome of 72 human fetal knee cartilage samples and identify 24 independent osteoa...

Here it is! The first paper from my lab is out today in #AJHG

In brief, we quantified the changing methylome through a large window of prenatal human articular cartilage development and identified methylation QTLs co-localising with 24 OA risk signals www.cell.com/ajhg/fulltex...

Thanks DJ Dan!

Yesterday I successfully defended my PhD thesis! Massively grateful to my supervisory team Prof John Loughlin and @grainofscience.bsky.social for their mentorship, guidance and support over the last few years. And thank you to @mcdeandres.bsky.social for making the long journey over from A Coruña!!

Today we have the seminar of @mcdeandres.bsky.social who has very kindly stayed on to tell us all about the world of chondrocytes 😃

Congratulations Dr @jackbroberts.bsky.social! Very proud to witness the first in person viva of one of my students (I know you weren’t really mine but I’ve claimed you!). Thanks so much to @mcdeandres.bsky.social and Luke Gaughan for examining 🥂