Cells, Genes and Molecules - Newcastle

Long telomere inheritance through budding yeast sexual cycles Abstract. The ends of linear eukaryotic chromosomes are protected from being recognized as DNA double-strand breaks by telomeres, containing repetitive DNA

academic.oup.com/genetics/art...

Telomeres outside the Goldilocks zone cause problems for yeast and humans A new study in GENETICS investigates the role of generational inheritance of long telomeres in yeast cells.

Long telomere inheritance through budding yeast sexual cycles. Blog article based on Theme research from Vasilisa Sidarava, Sarah Mearns and David Lydall. Congratulations team. genestogenomes.org/telomeres-ou...

MRC DiMeN Doctoral Training Partnership: Harnessing the power of RNA modification to develop new precision therapies for prostate cancer at Newcastle University on FindAPhD.com PhD Project - MRC DiMeN Doctoral Training Partnership: Harnessing the power of RNA modification to develop new precision therapies for prostate cancer at Newcastle University, listed on FindAPhD.com

Harnessing the power of RNA modification to develop new precision therapies for prostate cancer with Professor David Elliott and industry partner nanovery.co.uk www.findaphd.com/phds/project...

MRC DiMeN Doctoral Training Partnership: The ageing nucleus in the mammalian oocyte at Newcastle University on FindAPhD.com PhD Project - MRC DiMeN Doctoral Training Partnership: The ageing nucleus in the mammalian oocyte at Newcastle University, listed on FindAPhD.com

The ageing nucleus in the mammalian oocyte with Dr Suzanne Madgwick @suzannemadgwick.bsky.social www.findaphd.com/phds/project...

MRC DiMeN Doctoral Training Partnership: How do cells reset and then recall their transcription programme during cell division? at Newcastle University on FindAPhD.com PhD Project - MRC DiMeN Doctoral Training Partnership: How do cells reset and then recall their transcription programme during cell division? at Newcastle University, listed on FindAPhD.com

How do cells reset and then recall their transcription programme during cell division? With Professor Jonathan Higgins www.findaphd.com/phds/project...

MRC DiMeN Doctoral Training Partnership: Vision and Sensory Processing in Autism: Linking Lived Experience with Retinal Development at Newcastle University on FindAPhD.com PhD Project - MRC DiMeN Doctoral Training Partnership: Vision and Sensory Processing in Autism: Linking Lived Experience with Retinal Development at Newcastle University, listed on FindAPhD.com

Vision and Sensory Processing in Autism: Linking Lived Experience with Retinal Development (Supervised by Dr Rachel Queen @rachelq-ncl.bsky.social ). www.findaphd.com/phds/project...

Very pleased to share 4 exciting new PhD opportunities offered by our Cells, Genes and Molecules Theme in the Faculty of Medical Sciences at Newcastle University. Applications are open until the 4th of December. Please share and see below for project titles and links

We recently welcomed Dr Nicholas Brittain to the
LEGEND group, who has joined as a Research
Associate to investigate mechanisms driving
super-enhancers in paediatric leukaemia as part
of a research project funded by @cancerresearchuk.org

Want to know which kinase phosphorylates your site of interest in cells, go to kipik.dundee.ac.uk. The patented KiPIK screening method developed in Jon Higgins’ group ‪@medicalsciencesncl.bsky.social is now available as a new service from @mrcppu.bsky.social in Dundee. #kinase #molbiol #chembiol.

We have a Dr!!! 🎉 Well done Marc on defending your @nc3rs.bsky.social funded PhD! 👏👏👏 And thank you to James Henstock from @northumbriauni.bsky.social and Priscila Melo from @nclengineering.bsky.social for acting as Marc's examiners. #piroglab @cgm-newcastle.bsky.social

Transcription and Chromatin UK Manchester, UK 17-19 September 2025 Earlybird deadline: 17 July 2025

Taking place on 17-19 September 2025, Transcription and Chromatin UK will showcase cutting-edge research and is a ‘mustattend’ for anyone within the transcription and epigenetics community🧪. Register now: www.eventsforce.net/biochemsoc/2...

Dynamic Compression Improves Chondrogenesis in the Tissue Engineered Model of Cartilage Hyaline cartilage is a dense avascular tissue with low regenerative potential, present at the ends of the diarthrodial joints and in the cartilage growth plate. Skeletal diseases often result from ex...

Our new paper is out! Well done Marc, Thais, Fran et al @cgm-newcastle.bsky.social! And thank you to @nc3rs.bsky.social
and the #JGWPattersonFoundation for funding and support.
analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/...

Beyond the genome: Harnessing the power of super-enhancers for blood cancer - Cancer Research UK - Cancer News The mysteries of the epiregulome need to be tackled head-on if we are to get new precision treatments for blood cancers

Lisa Russell just wrote an insightful article for #CancerNews from @cancerresearchuk.org where she takes us through the promise of super-enhancer biology and what it means for cancer. Read the whole article here:
news.cancerresearchuk.org/2025/05/21/b...

RE-POST ALERT
Second chance to apply for the #bioinformaticspost funded by @cancerresearchuk.org to join our Leukaemia EpiGenomic and ENhancer Dysregulation group at @newcastleuni.bsky.social @nucancer.bsky.social, don't miss the opportunity! Closing date 1st May 2025! jobs.ncl.ac.uk/job/Newcastl...

Well done to my PhD Student Abby Brumwell on delivering a great talk to a full room at the @mosmedcdt.bsky.social annual conference this afternoon! #ProudPI @cgm-newcastle.bsky.social

Transcription and Chromatin UK is back for 2025 in Manchester! Make sure you register your interest to be kept in the loop about registration and abstract submission. www.biochemistry.org/events-and-t...

We're delighted to have Dr Kelly Coffey @coffeylabuk.bsky.social with us to share the story of her development as a researcher.

💬 She told us: "I hope by sharing my story, I can support the next generation of prostate cancer researchers to advance their own careers."

#ProstateCancerUK

How do cells reset and then recall their transcriptional programme during cell division? at Newcastle University on FindAPhD.com PhD Project - How do cells reset and then recall their transcriptional programme during cell division? at Newcastle University, listed on FindAPhD.com

www.findaphd.com/phds/project...

Uncovering the adaptation mechanism that generate dormant forms of Leishmania microbes with omics approaches at Newcastle University on FindAPhD.com PhD Project - Uncovering the adaptation mechanism that generate dormant forms of Leishmania microbes with omics approaches at Newcastle University, listed on FindAPhD.com

www.findaphd.com/phds/project...

The impact of the RNA exosome on ribosome specialisation in different cell types at Newcastle University on FindAPhD.com PhD Project - The impact of the RNA exosome on ribosome specialisation in different cell types at Newcastle University, listed on FindAPhD.com

www.findaphd.com/phds/project...

Understanding cellular rapid shape shift using molecular rulers at Newcastle University on FindAPhD.com PhD Project - Understanding cellular rapid shape shift using molecular rulers at Newcastle University, listed on FindAPhD.com

www.findaphd.com/phds/project...

Investigating the role of collagen glycosylation in joint development and homeostasis using stem cell models of neocartilage at Newcastle University on FindAPhD.com PhD Project - Investigating the role of collagen glycosylation in joint development and homeostasis using stem cell models of neocartilage at Newcastle University, listed on FindAPhD.com

www.findaphd.com/phds/project...

The role of membrane dynamics in the polarisation of cells during embryo development at Newcastle University on FindAPhD.com PhD Project - The role of membrane dynamics in the polarisation of cells during embryo development at Newcastle University, listed on FindAPhD.com

www.findaphd.com/phds/project...

Identifying quality control mechanisms in human skin and their role in the hallmarks of ageing at Newcastle University on FindAPhD.com PhD Project - Identifying quality control mechanisms in human skin and their role in the hallmarks of ageing at Newcastle University, listed on FindAPhD.com

www.findaphd.com/phds/project...

FindAPhD : BBSRC North East England BBSRC Doctoral Landscape at Newcastle University Apply for a PhD: BBSRC North East England BBSRC Doctoral Landscape at Newcastle University

Still time to apply for BBSRC PhD studentships in our Cells Genes and Molecules Theme @newcastleuni.bsky.social . Deadline 31st of March. An excellent range of project adverts to follow! www.findaphd.com/phds/program...

Rescuing bacterial genome replication: essential functions to repair a double-strand break and restart DNA synthesis Many antibiotics indirectly generate reactive oxygen species (ROS) that can damage bacterial genomes. Oxidised nucleobases become genotoxic when they are targeted for repair through excision, generati...

Excited to share with you the story that enabled me to start my own lab: what happens when the bacterial DNA replication machinery encounters single-strand discontinuities on template DNA? What is required for break repair and replication restart?
www.biorxiv.org/content/10.1...

Two postdoc posts currently advailable to work with Dr Lisa Russell on an exciting new project funded by CRUK - looking for a laboratory and a bioinformatic PDRA. Apply here: jobs.ncl.ac.uk/job/Newcastl... and here: jobs.ncl.ac.uk/job/Newcastl...
@nucancer.bsky.social

The impact of the RNA exosome on ribosome specialisation in different cell types at Newcastle University on FindAPhD.com PhD Project - The impact of the RNA exosome on ribosome specialisation in different cell types at Newcastle University, listed on FindAPhD.com

We have a 4 year PhD position available to study the impact of the RNA exosome on ribosome specialisation! Get in touch if you are interested or just apply. March 31st deadline.

www.findaphd.com/phds/project...

Investigating the role of collagen glycosylation in joint development and homeostasis using stem cell models of neocartilage at Newcastle University on FindAPhD.com PhD Project - Investigating the role of collagen glycosylation in joint development and homeostasis using stem cell models of neocartilage at Newcastle University, listed on FindAPhD.com

We're advertising a fully-funded BBSRC PhD studentship @newcastleuni.bsky.social to work on understanding the biology of COLGALT2 in cartilage using/developing cool model systems w/ Dr James Henstock at @northumbriauni.bsky.social. Pls reach out if you are interested in applying! bit.ly/3DiqHN9

Celebrated picture after examination of John Meyrick for his . From left to right examiner, Tom Nichols, PHD supervisor Uwe Richter, PhD Jon Meyrick , mentor Rob Taylor, and examiner Ray O’Keefe

🍾Bursting with pride and joy! Watching you grow as a scientist and individual has been incredible. Congrats, Jon, on truly earning your 🎓PhD! Thanks to all the amazing support @taylorlabncl.bsky.social
@cgm-newcastle.bsky.social
@mitonewcastle.bsky.social and examiners Ray O’Keefe and Tom Nicholls!