Silvia Turin

Circadian-informed modeling predicts regional variation in obesity and stroke outcomes under different permanent US time policies | PNAS Seasonal changes in time policy, such as switching between Standard Time (SDT) and Daylight Saving Time (DST), have been adopted by many countries,...

A simple way to help reduce obesity and stroke?
Stop the shifts in our clocks twice a year
www.pnas.org/doi/abs/10.1...

Can Supplements Boost Longevity?

? Such a Thing as Longevity Supplements
My thoughts (based on evidence) are included
www.nytimes.com/2025/09/11/w...

A child died from a rare complication of a measles infection contracted before s/he was old enough to be vaccinated. Another heartbreaking reminder of the danger that measles infections pose.

𝗨𝗻𝗲𝘃𝗲𝗻 𝗽𝗿𝗲𝗽𝗮𝗿𝗲𝗱𝗻𝗲𝘀𝘀
▪️ 17/36 countries have a national surveillance system
▪️ 15 have specific #IPC guidance
▪️ 29 report access to a mycology reference/expert lab
▪️ 23 offer reference testing

Our Preoccupation With Protein Intake The data on high protein diets, bars, supplements, and powders will surprise you

Aligned with my recent post
erictopol.substack.com/p/our-preocc...

Timely surveillance, reporting, and collaboration across sectors remain essential to reducing the impact of West Nile virus in Europe.

📊 Find the latest monthly data here 👉 wnv-monthly.ecdc.europa.eu

#WestNileVirus #VectorBorneDiseases #OneHealth #ECDC #EFSA #PublicHealth

Benchmarking progress in non-communicable diseases: a global analysis of cause-specific mortality from 2001 to 2019 From 2010 to 2019, NCD mortality declined in four of every five countries in the world. These improvements were not as large as the preceding decade for most countries, driven by smaller declines in m...

Chronic "non-communicable disease mortality declined in all high-income western countries, with Denmark experiencing the largest decline for both sexes and the USA experiencing the smallest decline."
www.thelancet.com/journals/lan... open-access @thelancet.com

Rapamycin may extend lifespans by protecting against DNA damage The drug rapamycin has been linked to a longer life and we're starting to understand how it might have this effect

The drug rapamycin has been linked to a longer life and we're starting to understand how it might have this effect

Just 1 minute of vigorous exercise a day could add years to your life People who do several very short bouts of strenuous activity each day are much less likely to die in the next few years than those who do no exercise at all

People who do several very short bouts of strenuous activity each day are much less likely to die in the next few years than those who do no exercise at all

Brain implant lets man 'experience joy' for the first time in decades A device that has been likened to a pacemaker for the brain has given a man with severe depression great relief

A man who had severe depression for more than 30 years has "experienced joy" after undergoing bespoke brain stimulation.

Covid-19 seems to age blood vessels - but only among women Women's arteries seem to be stiffer if they have had covid-19, with the same effect not being found among men

Covid-19 seems to accelerate the ageing of blood vessels, but only among women.

Vape mouthpieces could be swarming with fungi that harm airways Fungal species, one of which caused chronic bronchitis in mice, were collected from the mouthpieces of e-cigarettes used by daily vapers

The mouthpieces of disposable e-cigarettes used by daily vapers were swarming with fungal species, one of which caused symptoms of chronic bronchitis in mice.

p-Tau 217, Tau PET, and Cognition in Preclinical Alzheimer Disease This diagnostic/prognostic study examines longitudinal data from studies of older patients without cognitive impairment to consider whether plasma phosphorylated tau 217 and tau positron emission tomo...

p-tau217 predicts cognitive changes prior to any cognitive impairment (again)
"The era of disease-modifying therapy in Alzheimer's disease is just starting."
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...

The colour of your car has a big impact on urban heat Dark-coloured cars can make a measurable difference on nearby air temperature, and in cities of millions the effect can add up and noticeably increase how hot it feels

Dark-coloured cars can make a measurable difference on nearby air temperature, and in cities of millions the effect can add up and noticeably increase how hot it feels

We will soon be able to talk with other species. Which will be first?

Scientists have long and studiously avoided claiming that other animals have language. Now, using the power of AI, they are on the verge of deciphering one

Living at high altitude may help ward off obesity Children seem to be less likely to be obese if they live at high altitude, which may be due to its effect on metabolism and appetite

Living at high altitude may help ward off obesity, possibly due to its effect on metabolism and appetite.

Common artificial sweetener may interfere with cancer treatments People who consume some artificial sweeteners are less likely to respond to certain cancer therapies, potentially because of the impact on their gut microbiome

More research is uncovering that aritficial sweeteners aren't as harmless as we once thought. Not only may they increase hunger and raise blood sugar, but a new study finds they could also be interfering with crucial cancer treatments. www.newscientist.com/article/2490...

Vagus nerve stimulation receives US approval to treat arthritis The US Food and Drug Administration has approved a pill-sized device for treating rheumatoid arthritis, marking the first time the therapy has been approved for an autoimmune condition

The US Food and Drug Administration has approved a pill-sized device for treating rheumatoid arthritis, marking the first time the therapy has been approved for an autoimmune condition

Childhood Vaccination Rates Have Dropped Again, C.D.C. Data Shows

New federal data shows that vaccination rates among American children entering kindergarten fell during the 2024-25 school year, extending a worrying trend that began during the Covid-19 pandemic.

www.nytimes.com/2025/07/31/h...

Human exposure to PM10 microplastics in indoor air The ubiquitous presence of airborne microplastics (MPs) in different indoor environments prompts serious concerns about the degree to which we inhale these particles and their potential impact on huma...

"The microplastic (MP) 1–10 μm exposure estimates are 100-fold higher than previous estimates that were extrapolated from larger MP sizes, and suggest that the health impacts of MP inhalation may be more substantial than we realize."
journals.plos.org/plosone/arti...

Using mRNA, scientists overcome a key challenge to HIV vaccines Scientists used a mRNA-based vaccine to reliably trigger antibodies that block HIV infection in people and monkeys

Scientists used a mRNA-based vaccine to reliably trigger antibodies that block HIV infection in people and monkeys
www.statnews.com/2025/07/30/m...

Association of ultra-processed food consumption and MRI-based carotid plaque characteristics: results from the Atherosclerosis Risk in Communities study Ultra-processed food and beverage consumption has been linked with adverse cardiovascular events, yet its association with sub-clinical disease remain…

The more ultraprocessed food intake, the more atherosclerotic plaque in the carotid arteries (by MRI)
www.sciencedirect.com/science/arti...

Daily steps and health outcomes in adults: a systematic review and dose-response meta-analysis Although 10 000 steps per day can still be a viable target for those who are more active, 7000 steps per day is associated with clinically meaningful improvements in health outcomes and might be a mor...

What's the optimal number of steps of physical activity this is associated with multiple (9) favorable outcomes?
The largest, systematic review of 57 studies, 35 cohorts.
7,000 steps is clinically meaningful, benefit also seen for 4,000 steps cf 2,000 steps
thelancet.com/journals/lan...

Major Alzheimer's group says some blood tests may be used in place of brain scans for diagnosis A major Alzheimer’s disease medical group is recommending that specialists may use certain blood tests to help diagnose patients with cognitive impairment.

A major Alzheimer’s disease medical group is recommending that specialists may use certain blood tests to help diagnose patients with cognitive impairment in lieu of more complex and invasive tests.
www.statnews.com/2025/07/29/a...

But extreme exercise increases the risk of AF
accompanying editorial
bjsm.bmj.com/content/earl...

Obesity may come in 11 different types, each with their own cause Obesity could exist in many forms, which may benefit from different treatments and prevention strategies

There could be 11 different types of obesity, which may explain why some people with the condition don't lose weight with drugs like Ozempic.

Steadfast lifestyle changes seem best to improve cognitive decline Healthy habits like exercising and eating well really do seem to improve cognitive decline, particularly if followed in a dedicated way

Lifestyle changes like exercising and eating well really do seem to improve cognitive decline - particularly if they are applied in a steadfast, structured way.

American men are hungry for injectable testosterone A legion of new health clinics are serving it up

"Buff gym-bros and 'biohackers' inject themselves on TikTok while telling their audiences that they should be on 'T' even if their doctor disagrees." More on bro science
www.economist.com/united-state...

A terrific piece by @gidmk.bsky.social: clear, crisp, focusing only on evidence, data & science—not personalities!

In summary:

“What I like to focus on is the evidence. And the evidence, to me, is convincing that the pandemic started at the Huanan market in November 2019”

Great science writing👏

This is figure 3, which is FIB-SIMS imaging shows intracellular bioaccumulation of PFAS by E. coli ∆tolC.

The findings of a study in Nature Microbiology show the high bioaccumulation capacity of gut bacteria for PFAS, commonly known as forever chemicals. go.nature.com/4le7Svk #microbiome #medsky 🧪