Gina DeNicola

The best compliment 😁

Open Rank, Tenure Track Position – Metabolic Physiology - Salt Lake City, Utah job with University of Utah, Department of Nutrition & Integrative Physiology | 12844064 The Department of Nutrition and Integrated Physiology (NUIP) at the University of Utah seeks a Tenure Track faculty member at the rank of Assistant...

We have an Open Rank tenure-track faculty position in the Department of Nutrition & Integrative Physiology! Looking for a new colleague interested in making the University of Utah their new home to build a metabolic research program. Please share!
@uofunuip.bsky.social

W1TTW2 Professorship in Membrane Biology (m/f/d)

Job alert 📣 Our faculty looks for a Junior Professor W1 with tt to W2 in Membrane Biology! We are looking for #ECRs working on membrane biogenesis,contact sites,composition & other aspects of membranes in 🌱 and other organisms! DM me if you need more details!

jobs.ruhr-uni-bochum.de/jobposting/f...

My department at Dartmouth Medical School is hiring a tenure-track Assistant Professor. We are looking broadly for a biochemist or cell biologist. Please share this add! apply.interfolio.com/171438
@dartmouthbcb.bsky.social @futurepislack.bsky.social

A wonderful new opportunity - for both Rising Stars and established Research Leaders - to open a research lab in Ireland 🇮🇪🧪

Up to 3.25 million euro in support 🤩

#GlobalTalentIreland #Research #Ireland

Final call: Applications close September 2! KI is recruiting 20 Assistant Professors in a wide range of subject areas. We're looking for early-career researchers with strong scientific merits and future potential. All positions: ki.se/en/about-ki/...

Open Rank, Tenure Track Position – Metabolic Physiology - Salt Lake City, Utah job with University of Utah | 674355 The Department of Nutrition and Integrated Physiology (NUIP) at the University of Utah seeks a Tenure Track faculty member at the rank of Assistant...

We have an Open Rank tenure-track faculty position in the Department of Nutrition & Integrative Physiology! Looking for a new colleague interested in making the University of Utah their new home to build a metabolic research program. Please share! @uofunuip.bsky.social

Join us in at Moffitt! The Metabolism Program is recruiting at the Assistant Member (Assistant Professor) level. Review of applications starts September 1st. Please share! Details here: moffitt-cancer-center-careers.hctsportals.com/jobs/1883440...

Thanks to James Olzmann and Scott Dixon for organizing a fantastic #faseb #ferroptosis meeting in Scottsdale AZ! Lots of great science as ferroptosis continues to impact diverse biology and diseases. Can’t wait for the next one! @olzmannlab.bsky.social

Hot science and hot temperatures at the FASEB Ferroptosis conference start tonight. Seriously the highs are 110F here 🥵 but it's beautiful!

To distract from your own stress responses (!!!), check out this awesome new study from the Commisso lab linking metabolic stress to regulation of the pancreatic tumor microenvironment! ✨

It's my first #newPI roll call on BlueSky! Calling all new #cancer PIs who just started or who are about to start their labs! Please say hi and what you work on so I can follow you if I don't already! 😃

IMPORTANT IMPORTANT IMPORTANT IMPORTANT

Please watch the workshop video and COMMENT by 5:00 Monday 7/14

This is the source of the "no more model organism only grants in NIH-funded research" decree.

New work from @karrethlab.bsky.social!

FRA1 drives melanoma metastasis through an actionable transcriptional network https://www.biorxiv.org/content/10.1101/2025.06.07.658418v1

Unravelling cysteine-deficiency-associated rapid weight loss - Nature Conditional cysteine restriction in mice causes substantial weight loss, exceeding that seen with essential amino acid restriction, by activating the integrated stress and oxidative stress respon...

Unravelling cysteine-deficiency-associated rapid weight loss

www.nature.com/articles/s41...

Great work by @rushika-perera.bsky.social!

gumball and anais from the amazing world of gumball are sitting at a table ALT: gumball and anais from the amazing world of gumball are sitting at a table

REMINDER.....REMINDER......REMINDER

3 DAYS LEFT TO COMMENT ON SCHEDULE F

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Samantha Lewis

Our latest ‘Cell Scientist to Watch’ is Samantha Lewis. We caught up with Samantha to discuss her career path, the challenges for working on the ‘neglected’ mitochondrial genome and the exciting new frontiers in mitochondrial research.
journals.biologists.com/jcs/article/...
#JCSMitoSI

So excited for this!

Spatial mapping of the brain metabolome lipidome and glycome - Nature Communications Clarke et al. presents a framework for spatial analysis of the metabolome, lipidome, and glycome from a single tissue section using mass spectrometry imaging. Applying this approach, they revealed reg...

MALDI imaging of lipids, metabolites and glycans all on the same section! From Ramon Sun and colleagues. www.nature.com/articles/s41...

Figure showing that mitochondrial subpopulations proximal to endosomes and lipid droplets have similar proteomes, but both are significantly different from an average mitochondrial proteome.

In their Tools & Resources article, Corey Cunningham @cnfxc.bsky.social Jared Rutter @rutterlab.bsky.social @uofubiochem.bsky.social & team present their dual-purification system to isolate mitochondrial subpopulations.
journals.biologists.com/jcs/article/...
#JCSMitoSI #OpenAccess #Mitochondria

I am so very proud of Amanda for what she has accomplished in this study, of manuscript she wrote, and of her fearlessness in science. She is a superstar 🌟 I would also like to give a shoutout to our newest lab member Basma Yasseen who carried the revisions over the finish line 💪

Now came the real surprise! Tumors could form lacking both GSR and TXNRD1. Cytosolic disulfide reductase activity is necessary for the reduction of protein disulfides, cystine, and other molecules so how this is possible is still a mystery - and the focus on ongoing work!

Amanda found GSR deletion impaired tumor initiation, regardless of NRF2 status, while TXNRD1 deletion impaired progression to the adenoma stage specifically in NRF2 mutant tumors. This suggested they had non-overlapping roles at these stages.

NRF2 regulates both glutathione and thioredoxin recycling via glutathione reductase (GSR) and thioredoxin reductase 1 (TXNRD1), which have unique and overlapping disulfide targets. Amanda wondered whether these enzymes would be redundant or would they both be required for tumorigenesis?

Distinct roles for the thioredoxin and glutathione antioxidant systems in Nrf2-Mediated lung tumor initiation and progression Redox regulators are emerging as critical mediators of lung tumorigenesis. NRF2 and its negative regulator KEAP1 are commonly mutated in human lung ca…

🚨New paper alert! Led by former undergrad Amanda Sherwood @tophinogenesis.bsky.social (now PhD student at Northwestern), Amanda asked whether the glutathione or thioredoxin systems are necessary for NRF2's tumor-promoting effects in the lung. www.sciencedirect.com/science/arti...

...Michele Hartsough, Nicole Lopanik, Thekla Cordes, Gloria Asantewaa, Christina Adams, Tim Wang, Feroza Choudhury, Brad Mills, and Brad Smith! See you next year!

also thanks to all the workshop panelists, including @lyssiotislab.bsky.social @airdlab.bsky.social @colofflab.com @naama-kanarek.bsky.social @marasherman.bsky.social @louisefets.bsky.social @jcmunger.bsky.social @faubert.bsky.social @kristabledsoe.bsky.social ...

thanks to co-organizers @rushika-perera.bsky.social @muirlab.bsky.social @lydiafinley.bsky.social Dan Tennant, Dirk Brenner and Kristin Brown.