STY

The pariah formerly known as Prince

Everyone Else is Lying to You: My Book is Done! The pandemic’s biggest disinformation superspreaders are now in charge. How did this happen?

The sequel to We Want Them Infected is done!

COVID killed 1.2 million Americans while vaccines saved millions.

Yet, disinformation superspreaders were empowered, where they are taking a wrecking ball to science & medicine.

How did that happen?🧵

sciencebasedmedicine.org/everyone-els...

#ICOM & some of our members just published an article investigating the prevalence & prognostic association of #TERT expression in #meningiomas, with implications for diagnosis & treatment: bit.ly/4g8L0LZ

@gelarehzadeh.bsky.social @justinzwang.bsky.social @felixehretmd.bsky.social @syip.bsky.social

Image of a glass beaker breaking

Science is at the breaking point. With funding up in the air, labs are freezing hires and canceling plans. Innovation can’t wait. Read more in #TPhysMag: ow.ly/MZaL50WBucw @darachadwick.bsky.social 🧪

What Makes Someone Cool? A New Study Offers Clues.

www.nytimes.com/2025/06/30/w...

I think everyone needs this reminder. 🧪

Glioblastoma-instructed astrocytes suppress tumour-specific T cell immunity - Nature A population of TRAIL-positive astrocytes in glioblastoma contributes to an immunosuppressive tumour microenvironment and this mechanism can be targeted with an engineered oncolytic virus to improve o...

🧠 A recent article on glioblastoma-instructed astrocytes suppressing tumour-specific T cell immunity is now available in @nature.com. 📖 Full article: www.nature.com/articles/s41...
#EANOessentials #NeuroOncology #Glioma #ImmunoOncology

InterpolaAI, based on deep learning-based optical flow, restores and interpolates sparse image stacks.

This first example is a stack of histological images of a human pancreatic duct.

6 out of 7 images were missing or defective, all now generated.

Download here: www.nature.com/articles/s41...

"Gold standard science"

omicsomics.blogspot.com/2025/05/cliv...

APOBEC3 mutagenesis drives therapy resistance in breast cancer - Nature Genetics Analysis of a large cohort of metastatic breast cancer samples shows that APOBEC mutational signatures are enriched in post-treatment samples. APOBEC activity was also associated with mutations known ...

So excited to share our latest work with @saratchandarlapaty.bsky.social, Antonio Marra, Andrea Gazzo @mskcancercenter.bsky.social out today in @natgenet.nature.com! We uncover the function and mechanism of APOBEC3-driven therapy resistance in breast cancer. 🧵 1/
www.nature.com/articles/s41...

Earth, Wind & Friar

Wanted: a mean liberal Mark Carney shows how to be moderate in substance and populist in style

on.ft.com/4jD3Ag2

Two dogs peek over a barrier. Stock image.

A study in Scientific Reports shows that the dog-human relationship exhibits characteristics of both child and best friend relationships, combining the positive aspects of the parent-child bond with the minimal negative interactions of close friendships. go.nature.com/4cJtdcs 🧪

A schematic representation of clonal hematopoiesis of indeterminate potential (CHIP) and tumor-infiltrating clonal hematopoiesis (TI-CH) in a patient with lung cancer.

Both clonal hematopoiesis of indeterminate potential (CHIP) and cancer are more common with age. When they coexist in the same patient, CHIP cells may migrate to the tumor and have an adverse effect on overall survival. Full study results: nej.md/3EnzMVu

#MedSky #Hematology

Oh my God, this really is Hegseth.

Clonal Hematopoiesis as a Driver of Solid Tumors | NEJM Clonal hematopoiesis is the expansion of a genetically related population of hematopoietic stem and progenitor cells that disproportionately contribute to blood-cell production.1 Clonal hematopoies...

New evidence @nejm.org today that age-related clonal hematopoiesis (CHIP) has a driver role in evolution of solid cancers
www.nejm.org/doi/full/10....
www.nejm.org/doi/full/10....

When you scan the email from the editor and spot the words "accepted in principle"

This new report by several ICOM authors in JAMA Oncology highlights the importance of a role for #CytogeneticProfiling in the next iteration of #CNS WHO grading.

Read the full report now: bit.ly/3EmWNb2

@gelarehzadeh.bsky.social @justinzwang.bsky.social

👍

It is becoming apparent to me that having a moron achieve my goal of wrecking US economy will have unwanted side effects for Russia too..

Long reads such as @nanoporetech.com or @pacbio.bsky.social can provide insights into epigenetic. We
@yileifu.bsky.social & @timp0.bsky.social )summarize the latest #Bioinformatics approaches & why this matters! Out now @natrevgenet.bsky.social at:
bit.ly/4cjxUtl
@bcmhouston.bsky.social @jhu.edu

DOGE

The NatSec group chat shitshow illustrates why DEI is necessary. Otherwise, completely unqualified people will be hired just because they're white dudes.

This aged badly

Remember when Hillary's emails were a national security risk? Good times.