Joshua Frenster

We are excited to announce the first Western VGZT of Season 7! 🎉

🗓️ Thursday, October 2nd
⏰ 9:30 PDT / 12:30 EDT / 16:30 UTC / 17:30 BST / 18:30 CET

Our speakers:

👉 Antonia Weberling (@a-weberling.bsky.social)

👉 Sanjay Narayanaswamy (@sanjay-n.bsky.social)

Join the VGZT Eastern KEYNOTE lecture ☀️☕ TOMORROW

🗓️ Wednesday July 09
⏰ 13:30 IST / 17:00 JST / 8:00 UTC / 10:00 CET

Featuring:
1) Maithreyi Narasimha
👉Positioning tissues during Drosophila morphogenesis

Jose Silva @josesilvalab.bsky.social
👉From founder cells to organogenesis-stage embryo model

Save the date 📅! Our TriNational #devbio #stemcell Meeting 2025 will be held in Freiburg on Sept. 19th. As always, participation is free and talks will be selected from early career scientists. Joun us 😊
Info: devstemcell.org/home

@biozentrum.unibas.ch @uni-freiburg.de @igbmc.bsky.social

Changes to the 2026 and 2027 Work Programmes With the launch of the competitions for grants under ERC Work Programme 2026 in July of this year, several changes to the submission of applications and the evaluation of proposals will apply. The mai...

Big news! "researchers will be eligible to apply for a Starting Grant immediately after successfully defending their PhD, and at any time within the following ten-year period." #ERC #ERCstarting
erc.europa.eu/news-events/...

I'm excited to join @pritiagarwal.bsky.social and @tarafinegan.bsky.social as a co-organizer for the International Developmental Mechanics Seminar Series. The series will resume in September 2025, and call for speakers is now open! More info is on our new website: sites.google.com/view/devmech...

📢 Fresh off the press and featuring new exciting experiments! 🧪
We show how glycolytic activity instructs germ layer proportions through regulation of Nodal and Wnt signaling - happy to finally share this 😊
doi.org/10.1016/j.st...

B2B with @jesseveenvliet.bsky.social lab: doi.org/10.1016/j.st... 🤩

I'm really grateful for the large turnout of our Gastruloid meeting in Barcelona. Close to 100 researchers from 9 countries. With the gastruloid field expanding, I hope that the community stays this close and that the meeting becomes an annual tradition! #gastruloids #conference

The Barcelona #gastruloid meeting has been a blast. A witness to a field that is maturing and a statement of a promise that lurks in its horizon. Thank you @joshifrenster.bsky.social @dias-andre.bsky.social and Ulla Fiuza for the organization, @EMBO, @ERC and the community for support.

Thrilled to announce that I am looking for a Research Technician/Assistant to join my lab @imbavienna.bsky.social. Please consider applying if you’re enthusiastic about #devbio #stemcells #teamwork and excited to help shaping a new lab!

Thankful for any retweet! 🫶

imba.onlyfy.jobs/job/l6u2m980

Today's session was brilliantly opened up by David Turner @gastruloids.bsky.social giving a historical overview of where gastruloids came from, where we stand now, and what we as a community need to keep an eye on!

First day of our Gastruloid Meeting in Barcelona kicking off with amazing talks and discussion and a room filled with gastruloid enthusiasts! #gastruloids #conference

EOMES establishes mesoderm and endoderm differentiation potential through SWI/SNF-mediated global enhancer remodeling Schröder et al. describe the molecular functions of the Tbx factor Eomes, which, together with the SWI/SNF chromatin remodeling complex, establishes enhancer accessibility at mesoderm and endoderm (ME...

Excited to share our latest paper in DevCell! We show how EOMES and the SWI/SNF complex collaborate to drive chromatin remodeling, establishing mesoderm and endoderm differentiation potential.

Read the full paper here: www.cell.com/developmenta...

Do you want to illuminate your studies on innate immune responses? Our new biosensor monitors mtDNA from apoptosis, viral infections, other sources of dsDNA and environmental cGAMP. We also show that micro nuclei are poor activators of the #STING response

Thinking about the Spanish word "anoche", I realized that we forgot the English word "yestereve". Bring back concise words!

1/3 Embryogenesis requires fit cells. Here, following work from @miguel-torres-1963.bsky.social & @tristanrodriguez72.bsky.social and led by @joshifrenster.bsky.social we develop a #gastruloid model of #CellCompetition
www.biorxiv.org/content/10.1...
showing it recapitulates much of the embryo 🧵

A temporal coordination between Nodal and Wnt signalling governs the emergence of the mammalian body plan Nodal and Wnt signalling play an important role in the emergence of the mammalian body plan, primarily by orchestrating gastrulation and primitive streak formation. While the literature suggests that ...

www.biorxiv.org/content/10.1...

Here we explore the role of #Wnt and #Nodal signalling during mammalian gastrulation using #gastruloids. Building on the work of many labs, we propose that antagonistic signalling-dependent #modularity in the PS establishes the early mammalian body plan.

You're on it now!

Already on it :)

We've wondered for a while why #gastruloids are so sensitive to initial cell numbers. Here www.biorxiv.org/content/10.1... led by U, Fiuza, we explore this & observe effects of a number of variables on final structure and think what this tells us @ embryogenesis
#IInNumbersWeTrust #NotInTheGenes

For the dev bio crowd : there is a call for junior group leader at Institut Pasteur in Paris and one of the axis covered is related to development. Come and join us in this exciting place and become one of our colleague @devstempasteur.bsky.social
Please RT !!
research.pasteur.fr/fr/call/call...

When late science-nights reward you with those types of views, it makes it all worth it!

Is this what competition for nutrients looks like? I see no competition for space...

Perfect :)

A motivational "neural tube + somites sando" :)

Got it :)

💯

You're on it! :)

You're on it now :)

Next week, we’re back with two unique development talks: mouse gastruloids 🐭 with Kristina Stapornwongkul and turtles 🐢 with Agáta Horáčková & Barbora Straková. Mark your calendar—you won’t want to miss this!
🗓️ Dec 5, 12:30 EST / 18:30 CET / 17:30 UTC 🕥

Developmental signals control chromosome segregation fidelity during pluripotency and neurogenesis by modulating replicative stress - Nature Communications Here the authors show that the patterning signals WNT, BMP, and FGF control chromosome segregation fidelity during early lineage specification and neurogenesis, which could provide a rationale for the...

We recently uncovered that morphogenetic signals not only read our blueprints, but are key to maintain them, particularly in stem cells. Joint effort of numerous collaborations and the lead of Prof. Sergio Acebrón at @cosheidelberg.bsky.social

www.nature.com/articles/s41...