Janne Grünebast

RNA synthesis in Leishmania donovani is constitutive during stage conversion: a genome-wide PRO-seq analysis | Microbiology Spectrum Our data unequivocally show that life cycle stage-dependent gene expression in Leishmania donovani, the parasite responsible for the lethal Kala-Azar disease, does not involve regulated RNA synthesis. We used a genome-wide analysis of RNA synthesis of ...

Check out our newest study on transcription in Leishmania donovani. We show that transcription is truly constitutive during stage conversation on a genome-wide level using PRO-seq.
journals.asm.org/doi/10.1128/...

09.06.2025 13:18 — 👍 0    🔁 0    💬 0    📌 0

I travelled to Würzburg the last couple of days for the Joint Parasitology Spring Meeting from the DGP, BSP and SSTMP. I had the chance to present my project about the role of #lncRNAs in #Plasmodium #parasites. I met amazing researchers and I also got to meet old friends from my time at BNITM.

15.03.2025 12:36 — 👍 6    🔁 0    💬 0    📌 0

Genome-wide quantification of polycistronic transcription in Leishmania major | mBio Leishmania spp. are pathogens of humans and animals and cause one of the most important neglected tropical diseases. Regulation of gene expression in Leishmania but also in the related Trypanosoma is radically different from all eukaryotic model organisms,...

I am proud to share that the work from my time at the #BNITM is finally out in #Mbio today. Go check out the manuscript if you want to read about polycistronic transcription in #Leishmania parasites:
journals.asm.org/doi/10.1128/...

25.11.2024 16:00 — 👍 10    🔁 2    💬 0    📌 1

It was a pleasure presenting my research about #ncRNAs in #Plasmodium at the #EMBL next generation in infection biology conference. Such a great opportunity to network with institutes all across Europe and highlight the importance of #infection biology research! Thanks to the organizers.

15.11.2024 19:52 — 👍 3    🔁 0    💬 0    📌 0

Had a great time presenting my research on rRNAs in Plasmodium falciparum at #MPM2024 this year!

13.11.2024 16:06 — 👍 2    🔁 0    💬 0    📌 0