Journal of Cell Science

Giampietro Schiavo

Subhojit Roy

In our latest interviews, we hear from Giampietro Schiavo and Subhojit Roy @roylab-ucsd.bsky.social, past and present JCS Editors specialising in neuronal cell biology.

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Jamie Whitelaw

Read more about this research in our ‘First person’ interview with Jamie Whitelaw: journals.biologists.com/jcs/article/...

Jamie Whitelaw, @lmachesky.bsky.social and colleagues find that CYRI-B promotes focal adhesion turnover during cell migration.
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Today, our animation synthesizing decades of research on actin-mediated endocytosis in budding yeast was published:
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The result of a fantastic Iwasa-Drubin lab collaboration.

@margotriggi.bsky.social @jiwasa.bsky.social
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Also in Issue 22:
- Research Highlights on spindle assembly & cell migration
- Interviews with past & present JCS Editors Giampietro Schiavo & Subhojit Roy @roylab-ucsd.bsky.social
- Clathrin-mediated endocytosis at a glance
- Adherens junction Review
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JCS Cover: Cyri-b-knockout Cos-7 cells spread wide with actin-driven lamellipodia (blue), while microtubules (orange) do not always reach the cell edge, capturing the dynamic interplay of cytoskeletal systems. See article by J. A. Whitelaw et al. (jcs263646).

Issue 22 is complete

Explore our ToC: journals.biologists.com/jcs/issue/13...

Our cover image shows Cyri-b-knockout cells with actin-driven lamellipodia in blue and microtubules in orange. See article by Whitelaw, et al.
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Marie Hugenroth

Read more about this research in our ‘First person’ interview with Marie Hugenroth: journals.biologists.com/jcs/article/...

Figure showing the microscopy screen that was performed and which identified Pex31, Nsg1, Nsg2, Shr5 and Tcb1 as residents of the NVJ.

Marie Hugenroth, Maria Bohnert @bohnertlab.bsky.social and colleagues interrogate the role of Pex31 in metabolic adaptation of the nucleus–vacuole junction.
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JCS logo Cell Bio 2025 logo Our Editors will be attending Cell Bio 2025 Feel free to reach out with any questions you might have about publishing in the journal or other activities from our not-for-profit publisher The Company of Biologists. Picture of Seema Seema Grewal, Executive Editor, seema.grewal@biologists.com Picture of Amelia Amelia Glazier, Reviews Editor, amelia.glazier@biologists.com X: @J_Cell_Sci Bluesky: @jcellsci.bsky.social Instagram: cell_science_stories

Our Editors will be attending #CellBio2025 @ascbiology.bsky.social @embo.org.

Reach out to @seemagrewal.bsky.social and Amelia Glazier to discuss JCS, @focalplane.bsky.social and our other @biologists.bsky.social initiatives.

Sebabrata Maity

Read more about this research in our ‘First person’ interview with Sebabrata Maity: journals.biologists.com/jcs/article/...

Figure showing that perturbation of FAM134B leads to mitochondrial filamentation

Sebabrata Maity, Oishee Chakrabarti and colleagues discover that the ER protein FAM134B acts as a regulator of mitochondrial morphology.
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Xiang Wan (万向)

Read more about this research in our ‘First person’ interview with Xiang Wan (万向):
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Figure showing that Mei-38(176–242) binds to microtubules in interphase S2 cells and in vitro.

Xiang Wan, Hiroyuki Ohkura and colleagues find that spatially regulated phosphorylation aids in localised oocyte spindle assembly.
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The Company of Biologists 100 logo to the left and QR code to the right. Cartoon depiction of Mole, to the left, text to the right 100 extraordinary biologists Mole The columnist who writes under the pseudonym ‘Mole’ has been a regular contributor to Journal of Cell Science for over 20 years, providing humorous and often controversial perspectives on the challenges of the academic science system. #100biologists #biologists100

Our next extraordinary biologist is the columnist who writes under the pseudonym ‘Mole', a regular contributor to @jcellsci.bsky.social for over 20 years. #100biologists

Sorry for the typo, the tool is of course 'Toggle-Untoggle'.
Check it out here: journals.biologists.com/jcs/article/...

Nina Grishchenko

Read more about this research in our ‘First person’ interview with Nina Grishchenko:
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Figure showing the interactive segmentation refinement in Toggle-Untoggle – de-selection, merging and manual annotation.

In their Tools and Resources article, Nina Grishchenko, Michael Olson and colleagues present Toogle-Untoogle, a cell segmentation tool with an interactive user verification interface.
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Model for Mup1-mediated regulation of lifespan in response to SL synthesis.

In their Review, Daniel Adebayo, Hanaa Hariri and colleagues explore the roles of sphingolipids in organelle function, highlighting their metabolic connections to methionine restriction and aging.
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Günther Gerisch in 2022. Image credit: Martin Gerisch.

A life dedicated to science and research – a tribute to Günther Gerisch

An obituary from Mary Ecke, Markus Maniak and Annette Müller-Taubenberger
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JCS snapshot - Importin α regulates ciliogenesis and cilia length with implications for Xenopus nephrogenesis
@natmosqueda.bsky.social presents the key findings from their JCS paper with @psutton54.bsky.social & @brownlee.bsky.social @stonybrooku.bsky.social.
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Special Issue Imaging Cell Architecture and Dynamics Guest Editors: Francesca Bottanelli and Giulia Zanetti Deadline: 1 April 2026 Journal of Cell Science Call for papers logo Image of a cell

We invite you to submit your latest research to our upcoming special issue - Imaging Cell Architecture and Dynamics. This issue will be coordinated by two Guest Editors: @franbottanelli.bsky.social & Giulia Zanetti, with our Editor @guijacquemet.bsky.social. journals.biologists.com/jcs/pages/im...

Micrographs showing that myosin accumulation within IFM sarcomeres is abnormal when human UNC45 is expressed from the Actin88F-GAL4 promoter.

Daniel Smith, Sanford Bernstein and colleagues @sdsuresearch.bsky.social uncover the distinct impacts of human co-chaperone UNC45 paralogs on Drosophila muscle development and function.
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Cover image of Journal of Cell Science showing two cells expressing RFFL–EGFP and labelled for mitochondria and lipid droplets.

Why choose JCS?
- FREE to publish (OA options available)
- Fast-track option for papers with reports
- Preprint friendly, format-free submission + scoop protection
- Published by a not-for-profit publisher
- A tree planted for every peer-reviewed article🌳

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Ditipriya Mallick

Read more about this research in our ‘First person’ interview with Ditipriya Mallick: journals.biologists.com/jcs/article/...

Ditipriya Mallick, Siddhartha Sankar Jana and colleagues discover that cellular elasticity drives mechano-adaptation against fluid shear stress.
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Volume 138 Issue 20 | Journal of Cell Science | The Company of Biologists Journal of Cell Science publishes cutting-edge science encompassing all aspects of cell biology. It is published by The Company of Biologists, a not-for-profit organisation.

In the meantime, try a deep dive into our JCS Special Issue on Cilia and Flagella to fully immerse yourself into some great research, fantastic insight and provocative opinions: journals.biologists.com/jcs/issue/13... /fin

New JCS snapshot - Asymmetries in the three-dimensional beat of Chlamydomonas reinhardtii flagella revealed by holographic microscopy

Laurence Wilson presents the key findings from their recent JCS paper with Martin Bees.
#JCSciliaSI

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Our 53rd BSCB GenSoc UK Cilia Network e-symposium: JCS Special Issue on Cilia and Flagella was a smash hit! A staggering 🤩 435 participants 🤩 for outstanding and sometimes contentious takes on fantastic #cilia & #centrosome research. From 🇨🇱 Chile to 🇨🇳 China to the 🇨🇿 Czech Republic- #UKCilia2025 /1

Sudeshna Nag

Read more about this research in our ‘First person’ interview with Sudeshna Nag: journals.biologists.com/jcs/article/...

Figure showing that changes in PGAM5 oligomerisation and localisation play equally important roles in mitochondrial dynamics.

Sudeshna Nag, Angus McQuibban and colleagues identify that PGAM5 cleavage and oligomerisation equilibrates mitochondrial dynamics under stress by regulating DRP1 function.
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