Pablo Billeke

¿Tienes entre 40 y 55 años? ¡Participa en nuestro estudio! @pbilleke.bsky.social @alejandrafigueroa.bsky.social

Te invitamos a la charla Estimulación cerebral no invasiva y ejercicio en dolor crónico con la Dra. Edith Elgueta. 🗓 21/08/25 | ⏰ 14:30 hrs | 📍 UDD, modalidad híbrida.

Integrating and interpreting brain maps Tangled molecular, cellular, and dynamic undercurrents shape brain organization. An emerging paradigm across neuroscience domains is to comprehensively measure the spatial patterning of multiple biolo...

Integrating and interpreting brain maps: Trends in Neurosciences www.cell.com/trends/neuro...

Integrating and interpreting brain maps Tangled molecular, cellular, and dynamic undercurrents shape brain organization. An emerging paradigm across neuroscience domains is to comprehensively measure the spatial patterning of multiple biolo...

Integrating and interpreting brain maps: Trends in Neurosciences www.cell.com/trends/neuro...

Marcela Díaz, alumna del Doctorado en Neurociencias UC y del laboratorio NeuroCICS, representó nuestro trabajo en el Human Brain Mapping 2025 en Brisbane, Australia. 🧠🌏 #NeuroCICS #HBM2025

Is criticality a unified setpoint of brain function? Hengen and Shew propose that criticality—a state with scale-invariant dynamics—is a universal computational setpoint of healthy brains. Their meta-analysis of two decades of research reconciles contra...

Is criticality a unified setpoint of brain function?: Neuron www.cell.com/neuron/fullt...

Stimulation of the human ventral tegmental area increases strategic betting Hirschbichler et al. examine the effects of DBS-induced inhibition of the VTA on learning and decision-making. They find that while VTA inhibition does not

Stimulation of the human ventral tegmental area increases strategic betting url: academic.oup.com/brain/articl...

📅 30 de mayo | Día Mundial de la Esclerosis Múltiple
Nos sumamos a “Navegando juntos la EM” para visibilizar esta enfermedad.
🧡 18 h | Iluminación en La Moneda #iluminEMosChile

🧠 Seminario de Neurociencia y Neuroimágenes | 6 de junio, 12:00 h | U. de Concepción. Inscríbete 👉 forms.gle/uvrHQQz62zK6... 🍕 ¡Habrá coffee break con pizza! #Neurocics

𝗕𝗿𝗮𝗶𝗻-𝘄𝗶𝗱𝗲 𝗱𝘆𝗻𝗮𝗺𝗶𝗰𝘀 𝗼𝗳 𝗮𝗻 𝗲𝗺𝗼𝘁𝗶𝗼𝗻𝗮𝗹 𝗿𝗲𝘀𝗽𝗼𝗻𝘀𝗲

Looks like an interesting paper about brain-wide processes.
Sure to generate discussion.
www.science.org/doi/10.1126/...
#neuroscience #neuroskyence

7/7 🧵 Our findings could inform better diagnostics and treatments 💙, including brain stimulation ⚡or cognitive rehabilitation.
Understanding the neural basis of fatigue is key to improving quality of life in MS.

6/7 🧵 Cognitive fatigue—not physical fatigue—was consistently associated with these white matter patterns in PwRMS.
This suggests that fatigue in MS may arise from early, subtle disruptions in cognitive control and sensory integration networks.

5/7 🧵 Importantly, white matter microstructure (FA) 🧠 in short-range fibers connecting these areas, especially the left inferior frontal gyrus, was altered in PwRMS. This supports a distinct neuroanatomical basis for fatigue in PwMS 🌟

4/7 🧵
Regions linked to fatigue include:
🧠 Cingulate gyrus
🧠 Inferior frontal gyrus
🧠 Superior temporal sulcus
🧠 Insula
🧠 Transverse temporal gyrus
These are key areas for language, decision-making, emotional and social processing.

3/7 🧵 Using Bayesian regression models 📉(LASSO and Spike-and-Slab), we identified a specific pattern of white matter alterations that correlated with total and cognitive fatigue only in PwRMS.
@rodrigohch.bsky.social

2/7 🧵 Fatigue is one of the most disabling symptoms in MS. We compared 32 PwRMS and 29 healthy controls—both groups experiencing similar levels of fatigue—to explore brain-based differences using 🧠 MRI and diffusion imaging. @alejandrafigueroa.bsky.social @neurocics.bsky.social

White matter volume and microstructural integrity are associated with fatigue in relapsing multiple sclerosis - Scientific Reports Scientific Reports - White matter volume and microstructural integrity are associated with fatigue in relapsing multiple sclerosis

Why do we fatigue? Fatigue is very frequent in people with some pathologies as #MultipleSclerosis (MS). In our new paper, we show that white matter structure and connectivity in the brain are linked to cognitive fatigue. 🧵1/7🔗 www.nature.com/articles/s41...
‪@multiplesclerosis.bsky.social‬

El PPPD afecta la orientación espacial. Este estudio revela fallas en la navegación cerebral y mayor desorganización en pacientes. Lee más aquí: doi.org/10.3389/fneu... @pbilleke.bsky.social

¡𝐒𝐞 𝐚𝐛𝐫𝐢𝐞𝐫𝐨𝐧 𝐥𝐚𝐬 𝐩𝐨𝐬𝐭𝐮𝐥𝐚𝐜𝐢𝐨𝐧𝐞𝐬!
Inscríbete en la II versión del Diplomado en Investigación Clínica 𝟏𝟎𝟎% 𝐨𝐧𝐥𝐢𝐧𝐞.
𝐈𝐧𝐢𝐜𝐢𝐨: 𝟐 𝐝𝐞 𝐣𝐮𝐧𝐢𝐨 𝟐𝟎𝟐𝟓
👉 medicina.udd.cl/ver-diplomad...

White matter volume and microstructural integrity are associated with fatigue in relapsing multiple sclerosis - Scientific Reports Scientific Reports - White matter volume and microstructural integrity are associated with fatigue in relapsing multiple sclerosis

¡Nuevo artículo de Alejandra Figueroa! Un gran avance en nuestro laboratorio cambios en sustancia blanca y fatiga en EM. ¡Felicitaciones! #EsclerosisMúltiple #NeuroCICS #InvestigaciónUDD #CienciaConImpacto #AvancesEnNeurociencia
📌 www.nature.com/articles/s41...

¡Felicitamos a Nicolás Ferrer por aprobar su defensa de tesis! Celebramos este gran hito académico y le deseamos mucho éxito en sus próximos desafíos.
#neurocics #neurocicsudd #udd #neurociencias @pbilleke.bsky.social

Cells are swapping their mitochondria. What does this mean for our health? Researchers are studying why the energy factories are moving between cells and whether the process can be harnessed to treat cancer and other diseases.

Nature reports on how researchers are studying why mitochondria are moving between cells and whether the process can be harnessed to treat cancer and other diseases. 🧪

Jeremiah Cohen standing in front of a giant green neuron.

THIS IS ONE NEURON! Jaw dropping.

It distributes a particular neurotransmitter (norepinephrine) across the mouse brain; it’s a locus coeruleus neuron.

@jeremiahycohen.bsky.social and colleagues at the @alleninstitute.bsky.social are using new biotech to see things never seen before.

Quino

Age-related differences in 1/f aperiodic EEG/MEG signals can be driven by cardiac rather than brain activity 👇

#interoception 🧠🫀 #neuroskyence

elifesciences.org/reviewed-pre...

Dos millares de los mejores científicos del mundo denuncian “el peligro real” de Trump: “El sistema científico está siendo destruido” Miembros de las academias estadounidenses envían “un SOS” ante los recortes salvajes, la censura y los despidos ideológicos

🔴 Dos millares de los mejores científicos del mundo denuncian el “peligro real” de Trump: “El sistema científico está siendo destruido”

El prof. Fazio , llego a ocupar importantes cargos en organismos internacionales y la vicepresidencia del Banco Central, en el período 1970/1973. Además, fue profesor en las universidades de Chile, Academia de Humanismo de Cristiano y Arcis.
radio.uchile.cl/2025/03/28/f...

Large language models deconstruct the clinical intuition behind diagnosing autism Clinical assessment is the gold standard for autism diagnosis, and by using amply pre-trained language models paired with a suitable interpretability strategy, the native analysis of clinical intuitio...

Large language models deconstruct the clinical intuition behind diagnosing autism: Cell www.cell.com/cell/fulltex...

Felicitamos a Alejandra Figueroa Vargas, integrante de nuestro Laboratorio de Neurociencia Social y Neuromodulación, por su título de Doctora en Neurociencia en la PUC. Su trabajo en neurociencias cognitivas y clínicas impulsa la investigación en Chile. ¡Éxito en esta etapa!
#Neurocics