Brain Communications

Tscherpel et al. show that increased frontoparietal low-frequency coupling and disrupted network architecture early post-stroke reflect diaschisis and thalamocortical dysfunction. This study adds to the understanding of remote lesion effects 👉 buff.ly/lAhAWYl #stroke

Basche et al. explore the utility of proper name recall and practice effects as indicators of preclinical Alzheimer’s disease. They show that practice effects may be sensitive to PET biomarker status 👉 buff.ly/u1Dx0il #Alzhimers

Have you an outstanding paper published in Brain Communications during 2025? Take note of it for the Early Career Researcher Paper Prize! Nominations are Open! #ecr #paperprize #neuroscience 🧠
Link to form: buff.ly/7mJCpfH
More at: buff.ly/bLmnYye

New research shows #obesity may speed up brain aging, effects seen as early as age 40. Using brain scans and AI, scientists found obese adults had older-looking brains. Early weight management can help protect brain health #BrainHealth 👉 buff.ly/sy9Cwy9

Schwahn et al. report that individuals with primary brain calcification had elevated serum glial fibrillary acidic protein and neurofilament light chain levels indicating early, chronic astrocytosis and neuronal impairment 👉 buff.ly/SvTJ2gR

Gwak et al. find that sarcopenia was associated with dysphagia, early neurological deterioration, and decreased post-discharge recovery in acute ischaemic stroke, contributing to poor functional outcomes, especially in those with motor impairment 👉 buff.ly/nlknvJe

Zaic et al. report that relapsing-remitting multiple sclerosis patients show elevated cerebrospinal fluid T and B lymphocytes compared to controls. 👉 buff.ly/57Ah5kI

Please meet our Outstanding Reviewer (from Oct 2024 to Oct 2025)! Professor Bergsland has contributed significantly to our journal by providing an extensive amount of valuable peer reviews. Thank you for your work! 👉 buff.ly/T17hWPu #neuroscience

If you have read an outstanding paper published in Brain Communications during 2025, ✍️ take note of it for the upcoming Early Career Researcher Paper Prize! Nominations Open 1st December! #ecr #paperprize #neuroscience 🧠 🧠 🧠
Link to form: buff.ly/7mJCpfH

If you have read an outstanding paper published in Brain Communications during 2025, ✍️ take note of it for the upcoming Early Career Researcher Paper Prize! Nominations Open 1st December! #ecr #paperprize #neuroscience 🧠 🧠 🧠
More at: buff.ly/25QpvMm

Griffin et al. found targeted environmental enrichment proved more effective than B-TMT in thoracic spinal cord injury models. It enabled consistent and diverse motor engagement, promoted naturalistic behaviours, and supported broader functional recovery👉 buff.ly/2h5WXVC

Botta et al. report that emotional cues, particularly happiness, facilitate gait initiation in middle-stage Parkinson’s disease (PD) and healthy controls. This advantage is diminished in persons with PD 👉 buff.ly/jIPVnW4

In dementia-free older adults, higher plasma phosphorylated Tau-217 linked to poorer cognition, reduced brain thickness, and paired cerebrospinal fluid levels. Plasma phosphorylated Tau-217 may be a promising biomarker for cognitive decline 👉 buff.ly/jXUZo1N

Autosomal dominant spastic paraplegia type 4 (SPG4, SPAST gene) is a pure phenotype with progressive spastic weakness of the lower limbs. Miroglio et al. show mild cognitive dysfunction in a cohort of 20 SPG4 patients with frontotemporal hypometabolism 👉 buff.ly/KM48TXG

Inojosa et al. report that integrating MRI with gait analysis in people with multiple sclerosis identified four distinct mobility phenotypes using machine learning. Showing subtle gait impairments and compensatory patterns 👉 buff.ly/6g4hCoc #multiplesclerosis

Vaz-Salgado MA et al. analysed the cyclin pathway, retrospectively in patients diagnosed with oligodendroglioma by the WHO 2021 criteria. Showing that absence of p16 expression is associated with a worse prognosis 👉 buff.ly/OPPcLz7

If you have read an outstanding paper published in Brain Communications during 2025, ✍️ take note of it for the upcoming Early Career Researcher Paper Prize! Nominations Open 1st December! #ecr #paperprize #neuroscience 🧠 🧠 🧠
More at: buff.ly/25QpvMm

Salvato et al. report that proprioceptive deficits predict both disturbed sensation of ownership and anosognosia for hemiplegia following right-hemisphere stroke. Lesion mapping reveals damage to parietal regions and interhemispheric disconnections 👉 buff.ly/cEGwaft

Yan et al. reported that short-term high-frequency electrical stimulation of the epileptogenic zone during the interictal period consistently suppressed spike rate, amplitude and spectral power 👉 buff.ly/rFWmltV #epilepsy

Vallesi et al. report that individuals with functional paralysis and spinal cord injury show similar increases in functional connectivity between the right precentral gyrus and left insula during motor inhibition, despite intact behavioural performance 👉 buff.ly/wNl4YZE @vanessa-vallesi.bsky.social

Merenstein et al show structural brain connectivity, measured by high-resolution diffusion-weighted MRI, improved predictions of age-related alterations in brain function and cognitive performance, relative to standard spatial resolution buff.ly/0IOgtRX @jmerenstein.bsky.social @nba-eic.bsky.social

Magrinelli et al. define the pheno-genotypic spectrum of NDUFA9-related mitochondrial disease in 12 cases. Biallelic NDUFA9 variants cause complex I deficiency, with symptoms from neurodevelopmental delay with dystonia to isolated dystonia with basal ganglia MRI abnormalities 👉 buff.ly/t5XWVkv

Hall et al. investigate whether fractional anisotropy abnormality in temporal lobe white matter is spatially homogenous at differing depths in drug-resistant temporal lobe epilepsy. Full article 👉 buff.ly/wJhSphi #epilepsy

If you have read an outstanding paper published in Brain Communications during 2025, ✍️ take note of it for the upcoming Early Career Researcher Paper Prize! Nominations Open 1st December! #ecr #paperprize #neuroscience 🧠 🧠 🧠
More at: buff.ly/25QpvMm

Validate User

Feng et al. report that individuals with chronic neuropathic pain secondary to recurrent carpal tunnel syndrome show decreased cerebral blood flow and altered brain connectivity, which correlates with pain severity 👉 buff.ly/wJIkvRm #carpaltunnelsyndrome

Are you about to submit your paper to Brain Communications? If you are presenting this work at the #SfN25, show it to our Editor-in-Chief @tspiresjones.bsky.social who will be there! #neuroscience🧠

Are you attending SfN 2025 in San Diego? Use this opportunity to meet our Editor-in-Chief @tspiresjones.bsky.social . You can ask questions about the journal and learn about our exciting initiatives! #meettheeditor #Sfn25

Patel et al. show that multimorbidity's link to dementia risk depends on condition type and timing. Emphasizing the need to consider multimorbidity patterns in dementia risk assessment 👉 buff.ly/Prj5zIK
#dementia

Uenishi et al. report that Fingolimod reduces peripheral T cells but increases brain CD8⁺ T cells in P301S-Tau transgenic mice, exacerbating tau pathology and neurodegeneration. Findings highlight CD8⁺ T cells as therapeutic targets for tauopathy 👉 buff.ly/e4xXwyJ

Our newest editorial is out now! Our Editor-in-Chief @TSpiresJones talks about Public engagement in translational neuroscience: the good, the bad, and the ugly
👉 buff.ly/BNaHR3P
#translationalneuroscience