Kathrin Leppek

You are on such a run, Kelly! Congrats all around! 🎉

I got blocked by ChatGTP twice in one hour. Yes, I want to target RNA structure, that is my job. No, I do not want to harm people nor design a super virus bioweapon. While I should probably be happy this safety check is in place, I happily dive into the literature myself...

RNA-binding proteins and ribonucleoproteins as determinants of immunity - Nature Reviews Immunology RNA-binding proteins (RBPs) considerably expand the information content of the genome and can determine the lifespan, localization and function of RNA, thereby controlling when, where and how much pro...

Just out @natrevimmunol.nature.com
RNA-binding proteins and ribonucleoproteins as determinants of immunity
www.nature.com/articles/s41...
gives our perspective on this growing area of research. Special thanks to the editor Alexandra, for streamlining the manuscript.

Thank you Martin for writing this. Gave it to my lab to read right away.

Tom Cech on RNA research in Davos (video): www.weforum.org/meetings/wor...

And you got February!

We had a fantastic time at the Ribo-Seq workshop in Bonn. Thanks so much, Kathrin @katleppek.bsky.social and Ranen, for organizing! We learned a lot, and we're excited to use Ribo-Seq in future projects.

So far the feedback has been enthusiastic! The group is working on a wide variety of sample sets from diverse origins and biological questions in this first-of-its-kind practical course in the Cluster. We are very grateful for the support to teach immunologists how to study translation.

We are well into our 5-day Cluster Workshop on Ribosome Profiling (Ribo-seq) run by sabbatical scientist Ranen Aviner @czbiohub.bsky.social. We welcome PhDs and PIs from Bonn/Cologne for a hands-on and analysis course sponsored by the Cluster @immunosens.bsky.social @unibonn.bsky.social UKB.

Last Friday, we had an inspiring 10th Rhineland RNA Club meeting with top class speakers. It's great to see how the community is growing and the range of topics we're covering. Special thanks to Didier Stainier @stainierlab.bsky.social Simon Bekker-Jensen @bekkerjensenlab.bsky.social, Ranen Aviner!

Ranen Aviner is a @mpiage.bsky.social MPI sabbatical fellow shared in @inahuppertz.bsky.social‘s and my lab and is spending a 3-month sabbatical from Sept-Dec in our labs in Bonn/Cologne. He is also on the job market this cycle and every US institute will be lucky to recruit him. www.aviner-lab.org

It was a double ribosome talk day for us in Bonn with talks today by Ranen Aviner from @czbiohub.bsky.social and Simon @bekkerjensenlab.bsky.social from BRIC Copenhagen. Simon is visiting for the @rhinelandrna.bsky.social tomorrow and Ranen is a visiting scientist in my and Ina‘s lab. #RNAsky

Congratulation again Sedona! This is great to have you in Berlin. And two @devbiostanford.bsky.social alumni hires at once!!

Lab pumpkins 🎃 2025. Vivian, Ranen, Martin and Lisa were missed (2 people not from our team).

Really beautiful! 🤓

List of talks at the 10th Rhineland RNA Club meeting on 14 November @MPI Age in Cologne. Generously supported by the RNA Society, Lexogen, siTOOLs, Immagina Biotechnology, Twist Bioscience, and NEB.

We would like to invite all Rhineland RNA enthusiasts to attend our next series of in-person talks, featuring local and invited speakers. Highlights include the external talks by Didier Stainier, Simon Bekker-Jensen and Ranen Aviner. Please, register: tinyurl.com/RhinelandRNA

Congrats Meng2!! 🎉

@sedonamurphy.bsky.social Sedona, how did I not know you are at the MPI in Berlin now!! Welcome!! 🎉

🎓RNAmed met at LMU on May 19 for a Topic Day on the immune recognition of RNA. Special thanks to Prof. Veit Hornung, Prof. Kathrin Leppek, and Prof. Min Ae Lee-Krisch for sharing their insights & joining the panel discussion. 📅On May 20, PhD students shared their methods in our first Methods Seminar

I often think it would be great to have chloroplasts, do photosynthesis, and live off the sun.

I often think it would be great to have chloroplasts, do photosynthesis, and live off the sun.

Kathrin is definitely larger than life! Best recruit ever!!

This massive poster of the ad campaign for the new recruits at the @unibonn.bsky.social is the nerdiest version and the closest I’ll ever get to a superhero movie poster. #Bauzaun

“Government plays an incredibly important role in supporting innovative work and discovery research,” Nobel laureate Jennifer Doudna tells Jeffrey Goldberg at #TAF25. This is work that “just doesn’t get done in companies.”

Watch here: bit.ly/46a5DUE

Congratulations! 🎉

Snapshot of the Correspondence titled 'Translon: a single term for translated regions'

Many transcriptome regions are translated but not known to encode proteins. They remain poorly annotated and thus under studied, partly due to the lack of terminology for these features.

In @natmethods.nature.com we propose using "Translon" for any region decoded by the ribosome

We are happy to finally present our brand new lab website of the Leppek Lab! About time after 3.5 years of the lab. Perfectly in time for the #EMBLProtein meeting in Heidelberg where our 4 PhDs have posters and I have a talk! We would be happy about any feedback! 🎉 leppeklab.org

Is anyone in continental Europe looking for a lab manager? I have a fabulous candidate - let me know and please RT!

Amazing! Congrats for the first Huppertz lab preprint. So proud of you Ina! 💪🏻

Metabolic Crossroads: AMDHD2 Couples the Hexosamine Biosynthetic Pathway to Acetyl-CoA Homeostasis in Pluripotent Stem Cells Pluripotent stem cells (SCs) rely on metabolic rewiring to regulate self-renewal and differentiation. The hexosamine biosynthetic pathway (HBP) integrates multiple metabolic inputs to produce uridine ...

🎉 We’re excited to share our very first preprint!! 🎉
"Metabolic Crossroads: AMDHD2 Couples the Hexosamine Biosynthetic Pathway to Acetyl-CoA Homeostasis in Pluripotent Stem Cells"
👉 doi.org/10.1101/2025...

#FirstPreprint #StemCells #Metabolism #Epigenetics #AcetylCoA #HBP #Pluripotency #NewScience