ZMBH

3D Differentiation of Bone‐Marrow Derived Mesenchymal Stromal Cells into the Keratocyte Lineage for Corneal Bioprinting This study introduces a novel differentiation protocol for generating corneal stromal keratocyte-like cells using drop-on-demand bioprinting and a collagen-based hydrogel. The bioprinted constructs m...

The Duarte Campos lab has developed a novel protocol for the differentiation of mesenchymal stromal cells into corneal stromal keratocytes. These findings have been published in Advanced Healthcare Materials:

doi.org/10.1002/adhm...

01.08.2025 14:25 — 👍 0    🔁 0    💬 0    📌 0

A male-essential miRNA is key for avian sex chromosome dosage compensation - Nature Birds have evolved a unique sex chromosome dosage compensation mechanism involving the male-biased microRNA (miR-2954), which is essential for male survival by regulating the expression of dosage-sens...

@kaessmannlab.bsky.social has for the first time shown in an international collaboration, that survival of male birds crucially depends on a micro RNA for sex chromosome dosage compensation. The paper just has been published by Nature.
www.nature.com/articles/s41...

17.07.2025 08:42 — 👍 1    🔁 1    💬 0    📌 0

Valuable Funding for Five Researchers at Universität Heidelberg

Congratulations to Claudio Joazeiro @labjoazeiro.bsky.social being awarded an ERC Advanced Grant @erc.europa.eu. He is one of five scientists from @uniheidelberg.bsky.social who were successful in this round.

www.uni-heidelberg.de/en/newsroom/...
#ERCAdG #uniheidelberg #Universität #heidelberg

20.06.2025 10:38 — 👍 6    🔁 0    💬 0    📌 1

Flyer of the international meeting of the German society for Cell Biology in Heidelberg Oct 26-29 with all topics and speakers listed.

50 Years of Cell Biology: German Society for Cell Biology Meeting, October 26 – 29, 2025 | Heidelberg, Germany
Early bird registration deadline: June 15, 2025

03.06.2025 04:33 — 👍 33    🔁 20    💬 0    📌 1

Daniel Schindler being appointed as Professor in Microbiology

The ZMBH welcomes Daniel Schindler @danielschindler.bsky.social as new Professor in Microbiology joining us from Marburg's Max Planck Institute for Terrestrial Microbiology.

13.05.2025 15:53 — 👍 4    🔁 0    💬 1    📌 0

ZMBH research group leader Henrik Kaessmann @kaessmannlab.bsky.social has given a talk on the origin of humans for a general audience. This presentation is available on YouTube (in German): www.youtube.com/watch?v=WuYl...

25.04.2025 15:23 — 👍 1    🔁 0    💬 0    📌 0

Biologie aus dem Baukasten Ingenieure, Informatiker, Chemiker und Biologen kreieren künstliche biologische Systeme. Die synthetische Biologie verändert die Zukunft und definiert die Grenzen der Wissenschaft neu.

There is a German language video of a TV discussion on "Biology From the Building Block" in which ZMBH's Kerstin Goepfrich @kgoepfrich.bsky.social was one of the two invided experts: www.3sat.de/wissen/scobe...

24.04.2025 11:21 — 👍 4    🔁 1    💬 0    📌 0

Structurally heterogeneous ribosomes cooperate in protein synthesis in bacterial cells - Nature Communications Cells can simultaneously produce structurally dissimilar ribosomes, suggesting functional specialization of distinct ribosome populations. Here, the authors show that distinct ribosomes cooperate rath...

Another study has been published in Nat. Commun. by @pfeffercryolab.bsky.social. Collaborative work with @sergeymelnikov.bsky.social and @chillzaa.bsky.social from the UK looking at structural ribosome heterogeneity in bacteria and if this has an impact on function:
www.nature.com/articles/s41...

21.03.2025 11:18 — 👍 7    🔁 1    💬 1    📌 0

Genetic encoding and expression of RNA origami cytoskeletons in synthetic cells - Nature Nanotechnology This study introduces RNA origami nanotubes as self-assembling cytoskeleton mimics for synthetic cells. Expressed in vesicles from DNA templates, these RNA structures reach micrometre lengths, deform ...

The Goepfrich lab @kgoepfrich.bsky.social yesterday published the creation of cytoskeleton-like structures with different properties inside lipid vesicles using RNA origami: www.nature.com/articles/s41...

18.03.2025 08:14 — 👍 21    🔁 6    💬 0    📌 1

Structural mechanisms for centrosomal recruitment and organization of the microtubule nucleator γ-TuRC - Nature Communications The γ-TuRC plays a central role for nucleation of microtubules at the centrosome. Here, the authors dissect structural mechanisms for centrosomal recruitment and regulation of the γ-TuRC and identify ...

Work from ZMBH's @pfeffercryolab.bsky.social & the Schiebel lab togehter with the Gruss lab @unibonn.bsky.social reveals the structural mechanisms for centrosomal recruitment and organization of the human microtubule nucleator γ-TuRC: www.nature.com/articles/s41...

18.03.2025 08:01 — 👍 2    🔁 0    💬 0    📌 0

Developmental origins and evolution of pallial cell types and structures in birds Innovations in the pallium likely facilitated the evolution of advanced cognitive abilities in birds. We therefore scrutinized its cellular composition and evolution using cell type atlases from chick...

Today's Science paper by @kaessmannlab.bsky.social and two additional papers in the same iusse analyze the development of complex neural circuits in reptiles, birds, and mammals. These studies suggest that observed similarities result of evolutionary convergence. www.science.org/doi/10.1126/...

14.02.2025 10:11 — 👍 5    🔁 0    💬 0    📌 0

Full Professorship (W3) in Molecular Biology (f/m/d) with a Focus on Biological Engineering - 69117, Heidelberg (DE) job with Universität Heidelberg | 12834054 The Center for Molecular Biology of Heidelberg University (ZMBH), the Carl-Zeiss-Stiftung Center for Synthetic Genomics (CZS Center SynGen), and th...

We are recruiting a Full Professor in Molecular Biology with a focus on Biological Engineering. Details can be read up in the advertisement on Nature Careers. Please share with researchers who are active in this field.
go.nature.com/41IHN0i

08.01.2025 09:42 — 👍 0    🔁 1    💬 0    📌 0