Lydia Newton's Avatar

Lydia Newton

@lsnewton.bsky.social

Postdoctoral Research Fellow in the Towers Lab at UCL @towerslab.bsky.social

63 Followers  |  78 Following  |  3 Posts  |  Joined: 17.12.2024  |  1.7377

Latest posts by lsnewton.bsky.social on Bluesky

Huge congratulations Che! Well done!

10.07.2025 13:17 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Blizard Institute welcomes world-leading team of virologists

We are delighted to be joining the Blizard Institute in Autumn. The Blizard Institute is an amazing place for discovery science and we're looking forward to more transformative research and collaborations.

www.qmul.ac.uk/blizard/abou...

10.07.2025 13:05 โ€” ๐Ÿ‘ 24    ๐Ÿ” 7    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 2
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Towers Lab attending @londoninfectionecr.bsky.social (LINE) annual symposium. Great talk lineups at the Francis Crick Institute, London. #LINE #ScienceIsCool.

09.06.2025 12:42 โ€” ๐Ÿ‘ 9    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Virtual Virology is back - our first ever phage session. Do join us...

08.05.2025 18:09 โ€” ๐Ÿ‘ 22    ๐Ÿ” 12    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 3
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Microbiology and infectious diseases This page highlights recent articles on all aspects of bacteriology, mycology, parasitology and virology, covering the biology of pathogens, host-pathogen ...

Great seeing our recent antiviral PROTAC paper chosen by Nature Comms Editors as one of the 50 best papers in Microbiology and Infectious Diseases!

www.nature.com/collections/...

05.03.2025 16:16 โ€” ๐Ÿ‘ 10    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Macrocycle-based PROTACs selectively degrade cyclophilin A and inhibit HIV-1 and HCV - Nature Communications Targeted protein degradation has so far been rarely applied as an antiviral strategy. Here, the authors report that macrocycle-based PROTACs targeting host protein cyclophilin A, exploited during vira...

Antiviral drug development:

Small molecules inducing degradation of host protein cyclophilin A show #antiviral activity against HIV-1 & HCV

@towerslab.bsky.social โ€ฌ @lsnewton.bsky.social @claragathmann.bsky.social
@jollylab.bsky.social @alessiociulli.bsky.social

www.nature.com/articles/s41...

28.02.2025 15:01 โ€” ๐Ÿ‘ 11    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Thanks to all involved - @towerslab.bsky.social @claragathmann.bsky.social @katemorling.bsky.social @akreuschl.bsky.social @jollylab.bsky.social @alessiociulli.bsky.social & others!

14.02.2025 15:32 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

My PhD work is now published!

We designed PROTACs that degrade the viral cofactor CypA and demonstrated their antiviral activity against HIV & HCV. We anticipate broad efficacy against unrelated viruses and reduced evolution of viral resistance. They also make excellent tools to probe Cyp biology.

14.02.2025 13:25 โ€” ๐Ÿ‘ 20    ๐Ÿ” 2    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0
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Today @gogs-k.bsky.social, @tlhr.bsky.social, and I are launching @bindresearch.org, a UK-based not-for-profit research startup to deliver publiclyโ€“available tools and datasets to make intrinsically disordered proteins druggable. ๐Ÿ ๐Ÿ’Š๐Ÿงฒ ๐Ÿ’ป ๐Ÿฆ 

11.02.2025 09:26 โ€” ๐Ÿ‘ 75    ๐Ÿ” 20    ๐Ÿ’ฌ 3    ๐Ÿ“Œ 1

@lsnewton is following 20 prominent accounts