Carson Stacy

Study Finds High Protein Diet Improves Birds' Ability to Tolerate Infection Research identifies diet-driven differences in how canary immune systems respond to infection while revealing how a protein diet primes the birds to resist infection.

Research @UArkansas identifies diet driven differences in how canary immune systems respond to infection while revealing how a protein diet primes the birds to resist infection @uarkansas.bsky.social @sauerscientist.bsky.social @clstacy.bsky.social
news.uark.edu/articles/786...

That explains it!! Thank you 🙏

Time series of pubmed publications with t test or t-test

Thats a solid theory, but there must be something else going on. The t-test hasn’t seen an uptick.

Line graph over years of results per 100000 pubmed citations. Shows positive trend until 2015 when the tend has been going downward

Does anyone have insights into what is causing the recent downward trend in “t test” in PubMed citations? #stats
Source: esperr.github.io/pubmed-by-year

Improving transgene expression and CRISPR‐Cas9 efficiency with molecular engineering‐based molecules Graphical Headlights Artificial nucleic acid molecules (ANAMs) are combinations of aptamers binding to the key players of the innate immune response (IIR). ANAMs strongly inhibited the IIR in cells, ...

Here is that paper, dx.doi.org/10.1002/ctm2...
It’s just the first image I saw in a google search

If I had to guess, the Greek symbol was maybe pasted on after leading to the strange artifacts there.

I wonder how prevalent t-testing for proportions is, I feel like I see it often.

Bar chart of proportions of GFP positive cells with error bars and t-test derived significance markers.

You’re exactly right! Bar charts of proportions with error bars and t-test derived significance is more prevalent than id expect. I know folks are doing the best they can, but here’s an example from a recent paper.

Curious about folks thoughts on the widespread use of t-tests for proportion differences in publications. An urgent issue, or are there bigger fish to fry... What’s your stance? #stats #science

Fascinating! I wonder if we will see similar gains in efficiency with wild strains.

In your own words, write about what a p-value is, what it is for, and why it works.

Just as important as teaching how to use statistical tools in #science is teaching students why those tools work. Every #PhD graduate who uses #statistics in their field should be able to satisfactorily answer questions like the one below.
#edusky #academicChatter #statsky #phdchat #STEM

Alterations in Protein Phosphorylation and Arginine Biosynthesis Metabolism Confer β‐Phenylethanol Tolerance in Saccharomyces cerevisiae Through laboratory adaptive evolution, β-phenylethanol-tolerant Saccharomyces cerevisiae strains were obtained. Combined analysis of genomics, transcriptomics, phosphoproteomics, and lipidomics revea....

🧵 4/4 So, cells are being engineering as bio factories so that an artificial flavor can be reclassified to meet market demands. Science is amazing, and we deserve for it to prioritize people over profits. What should a “natural” label mean for our food systems?

Source: doi.org/10.1002/bit....

🧵 3/4 That is exactly what scientists have been trying to do with the second most common artificial flavor, beta phenylethanol (2-PE), for a while now. Only problem is it is toxic to the microbes engineered to produce it.

A recent paper has found new ways to make yeast resistant to this compound.

🧵 2/4 In the U.S., if a flavor substance is produced through a natural process, it can be a “natural flavor”, even if it is identical to a chemical flavor made in a lab.

Wait, with that definition, if we can engineer a microbe make the artificial flavor for us, it’s “natural” now!

🧵 1/4 Have you ever wonder how a flavor in food gets labeled “natural” or “artificial”? It seems like an easy question: comes from nature? natural. Made in a lab? Artificial. Sounds good to me, but let’s dig deeper…

ස්තුතියි. I’ve found it really challenging so far! I’m a total beginner. I had never heard of linguistic Sanskritization in Sinhala before. Thanks for introducing me to something new.

I’m trying to learn to read! I want to be able to communicate with my wife in Sinhala

I know plenty of folks in my grad school program who are self taught users of R for their research.

This open source course on R looks like a resource worth checking out: cs50.harvard.edu/r/2024/

useR! - The R User Conference on LinkedIn: #rstats #datascience #coding #rlanguage #statistics #computing #opensource… SAVE THE DATES!!! Great news: useR 2025 will take place at Duke University, in Durham, NC, USA, August 8-10! More details to announced shortly, so stay tuned…

SAVE THE DATES!!! Great news: useR 2025 will take place at Duke University, in Durham, NC, USA, August 8-10! More details to announced shortly, so stay tuned via duke-university-ocmd.read.axioshq.com/signup/user_...

www.linkedin.com/posts/user-c...

I’m extra grateful for the grateful R package’s cite_packages function. 🧪 Such a nice resource for easily making science more reproducible: pakillo.github.io/grateful/

What package brings you joy this holiday season? 📦

@jkpritch.bsky.social
Looks fascinating.
Is there a bluesky thread about this somewhere?

"We find that GWAS prioritize genes near trait-specific variants, while burden tests prioritize trait-specific genes."

Delighted to share a hobby project I’ve been working on: learning the Sinhala alphabet 🇱🇰

I made a free simple web-based letter learning game for myself, and want to share for others to enjoy!

clstacy.github.io/sinhala/

#LanguageLearning #Sinhala #SriLanka

This is a really useful feature, I always have to look up how to put special characters in axis labels.

Hi Erik, could you please add me, a PhD student in Cell and Molecular Bio, to the Science feed? My orcid: orcid.org/0000-0002-88...
Thank you!

Delighted to share new work from our lab:
MultiPerturb-seq 🎛️ ❌ ↕️

Over the last few years, we've been combining CRISPR screens with multimodal readouts of gene expression (RNA) and chromatin accessibility (DNA). In this study, we bring those together within the same cells.