Aiste Baleisyte

I am so thrilled to have been awarded the Kavli NSI Postdoctoral Fellowship to continue my research on the neural circuits of food intake control in the Friedman Lab.
@rockefelleruniv.bsky.social

A new hormone arrives in the middle of the night - Nature Medicine Jeffrey Friedman recalls the heady excitement when his group discovered leptin, a hormone that regulates appetite.

In this @natmed.nature.com piece, Rockefeller's Jeffrey Friedman recalls the heady excitement when his group discovered leptin, a hormone that regulates appetite.

1/6 Why does the brain maintain such precise excitatory-inhibitory balance?
Our new preprint explores a provocative idea: Small, targeted deviations from this balance may serve a purpose: to encode local error signals for learning.
www.biorxiv.org/content/10.1...
led by @jrbch.bsky.social

MapMySections - Data Challenge How do firing properties of a cell relate to its molecular cell type? We are seeking tools that can map spikes to brain cell types and visualize the results alongside existing knowledge.

Have you ever used a genetic tool and wondered what transcriptomic cell types it actually labels in the brain? Now is your chance to help solve this problem, through our MapMySections data challenge!

🧠📈 Submit your algorithm by May 30. alleninstitute.org/events/mapmy...

Laboratory of Neuroepigenetics -

We are looking for a new PhD student to join our lab of Neuroepigenetics at EPFL! Interested in deciphering the epigenetic mechanisms of memory formation, storage and change?🧠🧬Check out the specifics here: graefflab.epfl.ch

Congratulations to Shriya and the team for this important and beautifully done science!

Second, the group of Ralf Schneggenburger shows that a brain pathway from the posterior insula to the lateral amygdala transmits information that contributes to specific aspects of learning in response to fear - doi.org/10.1016/j.ce...

A crucial role for the cortical amygdala in shaping social encounters - Nature The posterolateral cortical amygdala and other connected brain regions have a key role in mediating the transition from investigative to aggressive behaviour in male mice.

1/4 I am very pleased to share this new manuscript, “A crucial role for the cortical amygdala in
shaping social encounters”, led by 2 spectacular postdocs, Dr. Tony Aubry who is on the job market, and coauthor @neuromanonyc.bsky.social

Read it here: www.nature.com/articles/s41...

Once you finish experiments late, go outside and campus is full of snow! The beauty of nature in the middle of Manhattan.
Happy #InternationalDayOfWomenInScience #GirlsInSTEM
@rockefelleruniv.bsky.social

A Neuropixels Opto probe with 3 blue emitters and 3 red emitters lighting up in succession, with corresponding neural activity in different layers of the cortex.

Neuropixels and Optogenetics are delighted to announce the birth of

Neuropixels Opto

Combining high-resolution electrophysiology and optogenetics

Today in bioRxiv

960 sites, 28 emitters, 2 colors

By Lakunina, @karolinazsocha.bsky.social, Ladd, et al

www.biorxiv.org/content/10.1...

(1/2)

NIH cuts billions of dollars in biomedical funding, effective immediately The move halts a large slice of money for most universities and research institutions virtually overnight, imperiling vital research in everything from cancer to heart disease.

Another assault on US competitiveness at a time when biomedicine is roaring with innovation, an own-goal in a high-stakes international tournament. Of course the real losers are American people needing medicines and cures.

www.washingtonpost.com/health/2025/...

GLP-1 and the Neurobiology of Eating Control: Recent Advances Abstract. Obesity is now considered a chronic relapsing progressive disease, associated with increased all-cause mortality that scales with body weight, af

Really proud to start the year by sharing our new review in @endosocjournals.bsky.social on the roles of GLP-1 in eating and obesity treatment, led by superstar postdoc @laurenjonesucl.bsky.social!

academic.oup.com/endo/article...

🧪🧠📈 #neuroscience #neuroskyence #GLP-1 #obesity #wegovy #ozempic

Kaplan Meier curve showing the cumulative incidence of type 2 diabetes in people given tirzepatide vs placebo

This month, a phase 3 trial of tirzepatide (a GLP-1 drug) found that it reduced the chances of developing type 2 diabetes by around 90% (!), among people with obesity and pre-diabetes.

That's a reduction if I ever saw one.
www.nejm.org/doi/full/10....