I want to thank my co-first authors Katja von Hoff and Denise Obrecht-Sturm, the supervisors of this study, Kristian Pajtler and Stefan Rutkowski, and of course all other co-authors and especially our patients and their families. There is still a lot of work ahead of us! 3/3
08.10.2025 17:35 β π 0 π 0 π¬ 0 π 0
By incorporating molecular and clinical risk factors into one stratification model, we anticipate that our work will help to design the next generation of ependymoma trials. This was a complex and long-lasting, but also very rewarding project. 2/3
08.10.2025 17:35 β π 0 π 0 π¬ 1 π 0
The ITCC Scientific Days in Newcastle have been a great meeting - thank you to the organisers! It was a pleasure to contribute to the excellent programme by presening our latest approach to #ependymoma stratification! #cancer #neurooncology
30.03.2025 15:05 β π 4 π 0 π¬ 0 π 0
YouTube video by NEJM Group
Blinatumomab in B-Cell Acute Lymphoblastic Leukemia | NEJM
Blinatumomab has been shown to improve outcomes in children with relapsed B-cell ALL, but the effects in children with newly diagnosed disease have been unclear. Research findings are summarized in a new Quick Take video. youtu.be/oADeOZpNYY8
#MedSky #Hematology
28.02.2025 20:11 β π 12 π 4 π¬ 0 π 1
Achievements such as this would have been thought of as impossible only a couple of decades ago. #Science delivers. But in a world where scientists are attacked, drowned in bureaucracy and regulations, and cut off their funding, miracles like the cure of #SMA will become rare.
20.02.2025 20:59 β π 2 π 0 π¬ 0 π 0
Chromothripsis in cancer - Nature Reviews Cancer
# REVIEW π¨
Simovic-Lorenz & Ernst from @dkfz.bsky.social discuss mechanisms of #chromothripsis, its impact on cancer and vulnerabilities of chromothriptic tumours.
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14.02.2025 18:17 β π 9 π 5 π¬ 0 π 1
Amazing initiative! ππΎππΎππΎ #childhoodcancer #globalhealth
11.02.2025 17:23 β π 3 π 0 π¬ 0 π 0
Gene editing technology began by people studying salt marshes. Ozempic began by folks studying the venom of Gila Monsters. Support for basic science has empowered us to understand our world. Tethering it to applications health has transformed and saved countless lives.
08.02.2025 13:45 β π 3339 π 724 π¬ 49 π 26
The Immunopeptidomic Landscape of Ependymomas Provides Actionable Antigens for T Cell-Based Immunotherapy
AbstractBackground. Ependymoma are primary tumors of the nervous system. Due to their growth pattern, many ependymomas can be managed with neurosurgical re
We are more than happy that our publication "The Immunopeptidomic Landscape of Ependymomas Provides Actionable Antigens for T Cell-Based Immunotherapy" is accepted by Neurooncology Advances.
academic.oup.com/noa/advance-...
Check it out ;)
@unituebingen.bsky.social
@hih-tuebingen.bsky.social
16.01.2025 14:42 β π 7 π 3 π¬ 0 π 1
Hey there! As always somewhat late to the latest social network party, but let's see whether bluesky has indeed become science twitter from a couple of years ago. Looking forward to meeting many new and familiar friends and colleagues here!
10.01.2025 22:35 β π 4 π 0 π¬ 0 π 0
PhD student @ DKFZ/Kitz
Developmental origins of pediatric cancer,
Pediatric glioma research
Actor π¬ 31
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I make videos and such, feel free to check out my links below π
https://linktr.ee/pat.mandziy
Independent group leader @COSHeidelberg, investigating developmental muscle precursor heterogeneity and its impact on lifelong muscle function and regeneration.
https://bageritz-lab.org
French national network for basic and translational research in pediatric oncology - Understand to treat #Medsky #Oncosky
#Genetics #neuroscience #cancer #singlecell #spatial #omics #datascience investigator, #STEM advocator, #fosteryouth protector, #wife #mom of 2 delicious daughters, views my own
Working on Reverse Translation and Adolescent & Young Adult Cancer at the Hopp Children's Cancer Center Heidelberg
Neurosurgical scientist - Director Translational Neurosurgery @FAU - Assoc. Prof. @Northwestern University- MILO Laboratory Erlangen & Freiburg
Associate Editor at Nature Reviews Cancer. IΒ΄m interestaed in all aspects of cancer research.
Clinician Scientist I Neuropathology @ University Clinic of Freiburg | Hem/Onc - Neuroimmunology - Precision medicine | EANO Youngster Committee
Junior research group leader and clinician scientist @Uniklinik Heidelberg&DKFZ. Epigenetics in brain tumors.
The Lyon-Marseille Center of Excellence in Pediatric Oncology Research (PEDIACRIEX23) - focusing on developmental alterations of #ChildhoodCancers for better care and prevention #Medsky #Science
Center of Excellence in the Life Sciences in Heidelberg and Mannheim, Germany
Brain tumor biologist at Heidelberg University
Neurologist and Immunologist at University Heidelberg and DKFZ with a focus on immunotherapy and cellular therapy of brain tumors and CNS autoimmunity
Chair & Prof, Dept of Neurological Surgery
Mayo Clinic Rochester William J and Charles H Mayo Professor
Editor-in-Chief, Neuro-Oncology Advances.
zadehlab.com
European Association of Neuro-oncology, multidisciplinary society, Clinical Trials, Research, Education #EANO2025 #btsm #neurooncology #braintumor #cancer | www.eano.eu
Head of the Tumor Microenvironment Laboratory at Institut Curie. #CancerResearch, #Neuro-oncology, #BrainTumor, #GBM, #Glioblastoma, #ResistanceMechanism, #TumorMicroenrironment, #TME, #Mechanobiology, #CellPlasticity
https://institut-curie.org/team/seano
