Tom Miller

CA2/3-dependent stability of frontal mnemonic representations predict episodic deficits in human amnesia Miller et al. use fMRI to demonstrate that human hippocampal CA2/3 subfield damage results in retrograde autobiographical amnesia and destabilized frontal autobiographical mnemonic representations. Mn...

New paper out in Cell Reports with @crosenthal.bsky.social and @michaelzandi.bsky.social
www.cell.com/cell-reports...

New paper in Cell Reports

CA2/3-dependent stability of frontal mnemonic representations predict episodic deficits in human amnesia

w/lead author @memory-miller.bsky.social

www.cell.com/cell-reports...

CA2/3-dependent stability of frontoparietal mnemonic representations predicts episodic deficits in human amnesia The hippocampus reconstructs past experiences by integrating sensory, perceptual, and conceptual information across a cortico-hippocampal autobiographical memory network (AMN). Here, in 18 human parti...

[New Preprint] w/ lead @memory-miller.bsky.social

CA2/3 damage destabilises frontoparietal mnemonic representations.
- Trial-by-trial instability predicts remote retrograde episodic deficits
- Sparse frontoparietal network vulnerability independent of CA1 co-lesions
www.biorxiv.org/content/10.1...

Bittersweet as this project began in 2022 with the late Eleanor Maguire. Those who know her will not be surprised to know she continued working on this up until the end.

This work was made possible with the support of
@wellcometrust.bsky.social

Decoding memory dysfunction in hippocampal amnesia The hippocampus reconstructs past experiences by integrating sensory, perceptual, and conceptual information across a cortico-hippocampal autobiographical memory network (AMN). Here, in 18 human parti...

Bittersweet but excited to share the preprint: "Decoding memory dysfunction in hippocampal amnesia." fMRI RDMs were used to assess how focal human hippocampal damage (N18) affects mnemonic representations across the autobiographical network @crosenthal.bsky.social www.biorxiv.org/content/10.1...