2025 at Redenlab was shaped by collaboration.
From researchers and clinicians to participants around the world, thank you for helping turn everyday speech into meaningful insight.
Hereβs a look at what we built together this year.
#bskySPEECHIES
18.12.2025 23:47 β π 0 π 0 π¬ 0 π 0
Rodent studies are essential, yet many assays donβt reflect human disease.
Motor & behavioural changes help, but mice also communicate ultrasonically - signals we canβt hear.
Adam will share how these patterns can better link preclinical models to human speech at SGV.
π§ͺ sgv.org/en/uuid/i/78...
26.11.2025 07:03 β π 1 π 2 π¬ 0 π 0
Publication highlights of the paper "Speech and language classification in the human phenotype ontology (HPO)". The right hand side features a photo of children undergoing speech therapy.
Key findings:
Speech & language difficulties often co-occur, but are distinct abilities.
- Speech: perception & motor production of sounds
- Language: understanding & producing messages (spoken/written)
Current classification systems (e.g. HPO) has overlapping and inconsistent speech & language categories.
Key findings:
Researchers proposed a simplified and revised classification framework that distinctly separates speech & language domains and their subtypes.
This framework will improve:
- Precision in diagnosis & phenotyping
- Targeted therapies for neurogenetic communcation disorders
- Data-driven discovery from medical records worldwide
To read full paper, check out link in caption.
Paper is published in European Journal of Human Genetics.
Author affiliations include Berlin Institute of Health, Murdoch Children's Research Institute, University of Melbourne, The Jackson Laboratory and University of Sheffield.
Prof Angela Morgan led team calling to better differentiate speech vs language in genetics.
Clearer terms = better diagnosis & care.
With input from Prof Adam Vogel, our CSO, advancing communication science.
In @ejhg-journal.bsky.social
π§ͺπ§ π www.nature.com/articles/s41...
#bskySPEECHIES
26.11.2025 06:23 β π 9 π 3 π¬ 0 π 0
Lottie from our team helped create fun language tasks in the GenV & Me app.
Families across Victoria can explore how their 4-years-old use language.
By recording and analysing these, we can spot early signs of language difficulties and help families get support sooner.
#bskySPEECHIES π§ͺ
15.10.2025 09:49 β π 2 π 0 π¬ 0 π 0
#bskySPEECHIES
08.10.2025 08:42 β π 0 π 0 π¬ 0 π 0
Cover page with title: Publication Highlights
"Examination of speech processing in noise reveals cognitive deficits in early Huntington's disease (HD)"
Key findings include:
Speech-in-noise processing reveals cognitive changes in Huntington's disease, even before symptoms appear.
Manifest HD: most impaired, particularly with multi-talker babble that strains executive function and working memory.
Premanifest HD: subtle but measurable deficits, especially when recalling single words without context.
Multi-talker noise hits hardest, reflecting working memory and attention challenges.
Speech-in-noise task predicted disease status with high sensitivity and specificity - a promising remote, non-invasive screening tool.
Everyday impact: Reducing background voices and using spatial cues can help people with HD communicate more easily
To read the full paper, check out link in caption.
Published in Cortex (with journal cover image attached).
Partners include Monash University, University of Melbourne, University of TΓΌbingen.
Struggling to follow conversations in noisy places could be a neurological condition.
New study w/ Monash, @unimelb.bsky.social, @unituebingen.bsky.social shows speech-in-noise tests may detect early cognitive changes before symptoms appear in Huntingtonβs disease.
π§ͺπ§ π redenlab.com/examination-...
08.10.2025 00:05 β π 15 π 3 π¬ 1 π 0
Stuttering Has Deep Genetic Roots and May Affect Your Ability to Clap to a Beat
A massive genetic study found that stuttering is not just about nurture and may link to processing rhythm itself.
Prof Angela Morganβs research, featured in ZME Science, found the first direct link between a rare PPID gene mutation and brain structure differences in people who stutter. Weβre grateful to have supported speech data collection.
π§ͺπ§ π www.zmescience.com/science/news...
#bskySPEECHIES
14.08.2025 02:01 β π 34 π 11 π¬ 0 π 0
Publication highlights: Phase 2a/b randomised placebo-controlled dose-escalation trial of triheptanoin for ataxia-telangiectasia: treating mitochondrial dysfunction with anaplerosis.
Key findings include:
1. Improved mitochondrial function was observed in patients with A-T treated with triheptanoin
2. Statistically significant and clinically meaningful improvements reported during the trial
3. Neurofilament light chain and interferon gene signature identified as promising biomarkers for monitoring disease progression and treatment response
4. Findings build on in vitro evidence showing that mitochondrial dysfunction in A-T cells is reversible and preventable with triheptanoin
5. Supports the potential of triheptanoin as a disease-modifying therapy for A-T
To read the full paper, check out link in caption.
Published in eBioMedicine.
Partners include: Queensland Children's Hospital, Wesley Medical Research, University of Queensland, Griffith University, Australian Institute for Bioengineering and Nanotechnology, University of Melbourne, CSIRO Australian e-Health Research Centre, University of New South Wales, John Hunter Children's Hospital, Royal Brisbane and Women's Hospital, Garvan Institute of Medical Research, QIMR-Berghofer Research Institute.
By Redenlab.
βͺNew trial shows triheptanoin may treat rare neurodegenerative disease A-T & flags biomarkers to track.
Thanks to UQ, @griffith.edu.au & more. Now in @ebiomedicine.bsky.social
π§ͺ redenlab.com/phase-2a-b-randomised-placebo-controlled-dose-escalation-trial-of-triheptanoin-for-ataxia-telangiectasia/
25.07.2025 05:36 β π 9 π 0 π¬ 0 π 0
That sounds really tough, and thanks for sharing with us. Changes like that are exactly what we're hoping to catch earlier with speech tools. π
23.07.2025 04:26 β π 1 π 0 π¬ 1 π 0
π§ͺ
23.07.2025 00:52 β π 0 π 0 π¬ 0 π 0
Thanks!
23.07.2025 00:51 β π 0 π 0 π¬ 0 π 0
Publications - Redenlab
Hi Monica, we'd love to be added to the feed. We're a research tech company focused on speech & language biomarkers in neuro & psych conditions (like ALS, Parkinsonβs, HD, etc.)
Check out some of our publications here! redenlab.com/publications/
Thanks for considering us.
23.07.2025 00:46 β π 0 π 0 π¬ 0 π 0
New publication by Redenlab: rapid repetitive syllable sounds associate with episodic memory, executive function, and working memory in cognitively healthy and subjectively impaired older adults.
Key findings include:
10-second βpa,β βta,β βkaβ speech test predicts cognitive function in older adults.
βPaβ test best linked to memory, executive function, and working memory.
Speech features add predictive power beyond age, education and mood.
Stronger executive function links in healthy adults; episodic memory links in those with cognitive concerns.
Speech-to-pause ratio and syllable timing were key markers.
The study supports remote, non-invasive early screening for Alzheimerβs risk.
To read full paper, check out link in post.
The study is published in GeroScience journal.
Partners include: University of Melbourne, University of Tasmania, Royal Hobart Hopsital.
Just 10s saying βpa ta kaβ can reveal early #Alzheimerβs risk.
Our new study at @geroscience.bsky.social shows speech changes predict memory, thinking skills pre-diagnosis.
Thanks to partners @wickingdementia.bsky.social, @utas.edu.au, UniMelb, Royal Hobart Hosp.
π: redenlab.com/rapid-repeti...
21.07.2025 07:37 β π 10 π 4 π¬ 2 π 0
Proud to contribute to a roadmap for advancing digital health tools in frontotemporal degeneration. Speech & language are key markers and our tech is helping lead the way.
For more info:
redenlab.com/redenlab-con...
15.05.2025 09:07 β π 0 π 0 π¬ 1 π 0
The official journal of the European Society of Human Genetics, providing insights into human genetics, genomics, molecular, clinical, and cytogenetics research
https://www.nature.com/ejhg/
Senior comms coordinator at the Garvan Institute, telling the human stories behind the science.
Former tech journo. Long-time dachshund enthusiast.
Celebrating the Australian National University science and medicine community ππΏπ₯π©Ί π§ͺ
#scienceanu
TEQSA provider PRV12002. CRICOS provider 00120π
Leading biomedical #openaccess journal, bridging the gap between basic and clinical research. Part of The Lancet Discovery Science. IF=10.8
π https://www.thelancet.com/journals/ebiom/home
We are at the forefront of #mentalhealth & #neuroscience #research. We collaborate across industries & disciplines to find answers to global #health challenges.
π¬ As the official research partner for UnitingCare, we are committed to delivering real health impact and further enhancing patient outcomes, while contributing to knowledge worldwide. #medicalresearch #healthresearch
https://www.wesleyresearch.org.au/
Discover more from ASHA's high-impact research journals: AJA, AJSLP, JSLHR, and LSHSS, all continuously published on the ASHAWire platform: pubs.asha.org
#bskySPEECHIES #SLPeeps #AUDPeeps
PAIN Reports is an official publication of the International Association for the Study of Pain (IASP). An open access multidisciplinary journal, PAIN Reports promotes a readily accessible forum that advances research on pain.
We are passionate about neuroscience. We have more than 25 individual research groups, with our major areas of research including multiple sclerosis, epilepsy and brain injury. We have over 200 staff members and 86 higher degree and honours students.
Australiaβs largest child health research institute | Top 3 globally for paediatric research impact
Transforming child and adolescent health through world-class science, clinical innovation & global collaboration.
1,800+ researchers | Based in Melbourne
Our mission is to accelerate the development of treatments and a cure while working to improve the lives of those living with Ataxia.
Welcome to Monash! Use #MonashUni in your tweets so we can like and share your stuff!
Located on the lands of the Kulin Nation. CRICOS number 00008C
Speech Pathology at The University of Melbourne is a global leader in speech, language, swallowing and digital health teaching and research.
We are part of the School of Health Sciences in the Faculty of Medicine, Dentistry and Health Sciences.
