eBioMedicine – The Lancet Discovery Science

Volatile pyrethroid spatial repellents for preventing mosquito bites: a systematic review and meta-analysis VPSRs offer protection from contact with mosquitoes, with semi-field studies reflecting field data and species-level differences observed. HLC provided the best quality data. Additional field studies ...

A relatively new class of insecticide called “spatial emanators” offer protection from mosquito-borne diseases such as malaria, dengue, West Nile, yellow fever, and Zika. This meta-analysis of more than 25 years of research provides clarity on how to test these products and how well they work.

Summary of main changes in CONSORT 2025. Copyright: 2025 The Author(s). Published by Elsevier Ltd. CC BY 4.0

First published in 1996, the CONSORT statement was designed to improve the quality of reporting and provide a minimum set of items to be included in a report of a randomised trial.

Now, there is an updated 2025 Statement.

Find it here: tinyurl.com/2s3hv3yx

Antipsychotic and pharmacogenomic effects on cross-sectional symptom severity and cognitive ability in schizophrenia Our results confirm the importance of taking account of medication history (and particularly antipsychotic type and dose) in assessing potential correlates of cognitive impairment or poor functioning ...

📝 NEW on schizophrenia: @cumedicengage.bsky.social researchers found links between 💊 medication variables & cognitive ability & 🧬 pharmacogenomic variation with positive & negative symptom severity ✨. Based on dimensions from a CFA of validated questionnaires 🧑‍💻
Funding: @mhrukcharity.bsky.social

Common chemicals in plastic linked to over 350,000 deaths from heart disease Researchers estimate that exposure to phthalates contributes to 13 percent of all heart disease deaths in people between 55 and 64 years old each year.

A set of chemicals found in food packaging, plastics, and lotions and shampoos has been linked to hundreds of thousands of deaths from heart disease, according to a study published Tuesday in the journal eBioMedicine.

Cover figure presenting main results from the paper. Left: altered spectral power and covariance difference between AD progressers and stable MCI patients. Right: multivariate analysis, highlighting the complementarity of MEG covariance spectra, MRI cortical volumes and baseline control measures.

🩺🧠 ✨Excited about our latest work published in @ebiomedicine.bsky.social! In the BioFIND dataset, we found that brain activity provided unique information about progression to Alzheimer’s Disease (AD). #neuroskyence Paper: www.thelancet.com/journals/ebi...; Thread 🧶 ⤵️

Single-cell multi-omics profiling uncovers the immune heterogeneity in HIV-infected immunological non-responders Our study provides new insights into the pathogenic mechanisms behind immune recovery failure in INRs, suggesting that IFN signalling might be involved in the development of CD4+ T cell exhaustion. Th...

🧬🔬 New study reveals immune heterogeneity in HIV non-responders! Key genes and pathways linked to CD4+ T cell exhaustion and interferon signalling identified. 📊🦠 #HIV #Immunology #Research #eBioMedicine #openaccess

Insights into maternal sleep: a large-scale longitudinal analysis of real-world wearable device data before, during, and after pregnancy This study revealed a previously unquantified initial increase in sleep followed by decreases in both quantity and quality as pregnancy progresses. Sleep deficits persist for at least 1.5 years postpa...

www.thelancet.com/journals/ebi...

🌙 New study on maternal sleep! 🌙 Using Fitbit data, researchers found: 🔹 Total sleep time peaks at 10 weeks of pregnancy. Light sleep ⬆️, deep & REM sleep ⬇️ Postpartum sleep deficits last 1.5 years
Clinicians can use this info to better support moms. 🤰🔬
Link in comments 👇 #MaternalHealth #Sleep

The March issue of eBioMedicine is now online! 🧬🔬 Hot off the press, exciting new #openaccess translational research on #obesity, #ibd, #t1d, #tuberculosis, #senolytics, and more!

📖🔍 Read now: all free, no paywall: www.thelancet.com/journals/ebi...

An LNP-mRNA vaccine modulates innate cell trafficking and promotes polyfunctional Th1 CD4+ T cell responses to enhance BCG-induced protective immunity against Mycobacterium tuberculosis These findings of a protective LNP-mRNA vaccine for TB highlight the potential of the LNP-mRNA platform for TB control and support further research to facilitate translation to humans.

🚀 New TB vaccine data! The mRNACV2 LNP-mRNA vaccine enhances BCG efficacy, boosting Th1 CD4+ T cells & reducing lung bacterial load in mice. 🌍💉 #VaccineResearch #tuberculosis #tb #immunology #mRNA #GlobalHealth 👇👇read for free #openaccess
www.thelancet.com/journals/ebi...

Editor-in-Chief, The Lancet Regional Health - Africa Do you enjoy using science to drive change in the world? Would you like to develop and launch an online-only gold open access journal for The Lancet. About our Team The Lancet Regional Health -Africa ...

Exciting new Lancet role ✨

This autumn, our Group is launching an OA journal dedicated to the unique health challenges on the African continent: The Lancet Regional Health—Africa 🌍 To lead this important endeavour, we are searching for an Editor-in-Chief. Find out more & apply ⤵️ bit.ly/3Xp919w

Interpretation of indoor air surveillance for respiratory infections: a prospective longitudinal observational study in a childcare setting Our results suggest that air sampling could provide sensitive, responsive epidemiological indicators for the surveillance of respiratory pathogens. Using air CO2 concentrations to normalise such signa...

New #kuleuven study: indoor air sampling to monitor respiratory infections in childcare settings. 🧒🏽🏫 Key findings: 🔬 Sensitive pathogen detection 🌬️ Correlation with CO2 & infection rates 📈 Early outbreak warnings
👇 www.thelancet.com/journals/ebi...
#PublicHealth #Epidemiology #RespiratoryInfections

The February issue of eBioMedicine is live! On the cover:
✒️ Editorial: Wildfires, smog, and the threat of #airpollution to health🫁 Research: Epithelial stem cells for #IPF therapy
🧠 Review: Synapse vulnerability in #Alzheimer’s disease
Read #openaccess 👇https://www.thelancet.com/journals/ebiom/home

Using multiomic integration to improve blood biomarkers of major depressive disorder: a case-control study Informational gain from multiomic integration had already been documented in other medical fields. Our results pave the way toward similar advances in molecular psychiatry, and have practical implicat...

Now online: By analyzing gene expression, DNA methylation, and miRNAs in blood, researchers found that sex-specific approaches boost predictive accuracy. This could lead to personalized mental health diagnostics and treatments. #MDD #Biomarkers #depression
👇 www.thelancet.com/journals/ebi...

A systematic analysis of the contribution of genetics to multimorbidity and comparisons with primary care data Most pairs of chronic conditions show evidence of shared genetics, and co-occurrence in primary care, suggesting shared mechanisms. The identified patterns of shared genetics, negative correlations an...

Now online: The GEMINI study analyzed millions of records, and identified multiple chronic condition pairs with shared genetics, indicating potential common mechanisms. 🧬🔗
Read for free online here 👉 bit.ly/4aNoXb3
#Genetics #Multimorbidity #Research #openscience @uniofexeternews.bsky.social