Ben GT Coumbe

"The latest wave of migrants is building careers here — and is seeing pay progress nicely."

Excellent analysis by @tomcalver.bsky.social citing research by @benbrindle.bsky.social @msumption.bsky.social & me on migrants' earnings.

www.thetimes.com/comment/colu...

The bottle tops that don’t separate 🤯

Please spare a thought for James Dyson, the Brexit-voting billionaire who bought up 33,000 acres of farmland to avoid tax then moved his business to Singapore. He's the real victim here.

“Everybody who leaves Twitter lives in a bubble. They don’t want to interact with people who have thoughts and values that differ from their own.”

Listen buddy I’m just trying to escape the sex bots

Wonderful introductory feed for usability!

Thread for those new to BlueSky. First of all, welcome. It feels like a safer space, doesn’t it? But also perhaps a bit disorienting initially? Here’s some tips for getting your bearings.

for anyone trying to extricate yourself from the clutches of Amazon: bookstores make more than a third of their money between now & New Year’s, & most bookstores ship nationwide 💌

📌

Anti‐retinal Autoantibodies in Hydroxychloroquine Eye Toxicity Objective Autoimmune retinopathy and hydroxychloroquine (HCQ)-related retinal toxicity share many similarities, raising the possibility autoimmunity plays a role in HCQ retinopathy. The objective of...

Among 270 patients with systemic lupus erythematosus, those with HCQ retinal toxicity had a higher likelihood of testing positive for anti-arrestin and anti-PKM2 antiretinal autoantibodies, which could be potential new biomarker for risk of developing HCQ eye toxicity

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🩺 Rheumsky

Gout flares pretreated, prevented, or experienced over the past 12 months by reporting status

A survey of US adults with gout estimated total gout flare burden to be 6.6 gout flares per year. Most gout flares were not reported to physicians 🩺

In ACR Open Rheumatology
acr.tw/48La0Fl

Figure: Gout flares pretreated, prevented, or experienced over the past 12 months by reporting status

To B or Not to B - CAR-T Cells Enter the Treatment Arena of IMIDS A video from William Rigby, posted on Aug 29, 2024.

To B or Not to B - CAR-T Cells Enter the Treatment Arena of IMIDS | VuMedi https://buff.ly/40DQwQY

I wish we could sue leaders who deny climate crisis

I also had some time out. I have found getting a Whoop wrist band quite revolutionary in terms of making sure I am healthier. It gives you accountability and a framework.

I think this is more that the US Medical Degree is an MD.. versus the UK where it is the alphabet salad of BMBCh, MBBS, MBChB, MBBChir …

To be fair the diet and sleep is the worst. Please donate fresh fruit rather than the dairy milk tray! I now order meals specifically for nights and freeze.

What is the difference between a frog and a toad? Ever wondered what the difference between a frog and a toad is? Find out all about these amphibians and why they're so different.

A bit of evolutionary biology for a Saturday morning*: all toads are frogs but not all frogs are toads. And the distinction between toads and frogs is just that toads tend to be terrestrial, whereas frogs tend to be more aquatic, with wet skin. 1/6
www.woodlandtrust.org.uk/blog/2024/02...

Where is this? Wales? Looks gorgeous!

A 12 lead ECG and I can’t really describe it without giving it away but the caption says VERY HIGH HEART RATE and you know what sometimes computers do get it right, it is indeed jolly fast

Lots of people posting under #medsky today. I am do not possess social skills such as a desire to engage in helloing, but what I do have [Liam Neeson voice] is a very unique set of ECGs

Here’s the first! I’m on call so might not reply straight away but tell me what you think is going on

Arthritis & Rheumatology Immunology for the Rheumatologist review series banner

New installment in the Arthritis & Rheumatology Immunology for the Rheumatologist review series 🧪

Macrophage activation syndrome

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Pictures only please

The lack of negativity is just refreshing

#MedTwitter #HiSciSky #MedSky #ImmunoSky

Resident doctor in London. Interested in immunology, rheumatology, autoimmunity, tolerance, T cells, immune checkpoint inhibitors, CAR T cells.

Interested in postgraduate medical education #MedEd and service design.

Also interested in 🍷🐶🏉🎾

Done. Hello world! #ImmunoSky

Graph of maternal mortality rate against year for the UK. Rate bounces until and down around 500 deaths per 100,000 births until about 1940, when it falls sharply. It’s been very low (~1–3 per 100,000) ever since.

This graph is astonishing. The people that bang on about “natural birth” and “women have been doing this forever without help” need to be forced to stare at this until their eyes water.

All - Bluesky Directory A curated collection of all things relating to the Blue Sky social media platform.

At last, there's a searchable directory of Bluesky starter packs, courtesy of @mubashariqbal.com! Just one more way third-party developers are helping to make this place better.

Search starter packs by keyword, and sort by "Uses" to see which ones people are finding the most helpful

Figure 1. Rare germline variant analysis. (A) The number of variants identified in eachpanel (CHIP-associated, Autoinflammation and Type I Interferonopathy) was normalisedto their corresponding gene panel size (gene count). Bar charts for each segmentillustrate the proportion of AOSD and HC cohorts (%) carrying a rare germline variant ineach gene panel. (B) The frequency of cases carrying rare variants across genes in theautoinflammation gene panel in each cohort. (C) Summary of the rare germline variantsshared by more than one AOSD case, colour coded to reflect the associated gene panel:CHIP (brown), Autoinflammation (orange), Type-I Interferonopathy (blue). (D) Theproportion of each cohort (%) carrying multiple variants across all gene panels

Genetic and biomarker investigation of underlying pathology and potential treatment targets for adult-onset Still’s disease. Results reveal genetic complexity in AOSD and demonstrate potential of ASC/NLRP3 specks assay for disease stratification and targeted treatment

In A&R
acr.tw/3YQmAzP
🩺

I am in desperate need of this too!

The final piece of advice I would like to give to new folks tonight is that Bluesky will be what you make of it. When I came over from the former Twitter, I resolved to be more kind to others here than I was over there. That choice has made being here so much better. Keep it in mind for yourself.