Silvia Paracchini's Avatar

Silvia Paracchini

@silparacchini.bsky.social

Prof of Neurogenetics & Genomics @St Andrews and Bonn; interested in cognition, neurodevelopment, dyslexia and handedness. Co-Chair of the @sldnetwork.bsky.social. Made in Italy. https://neurogenetics.st-andrews.ac.uk/

717 Followers  |  753 Following  |  257 Posts  |  Joined: 28.09.2023  |  1.9889

Latest posts by silparacchini.bsky.social on Bluesky

Many congratulations Bela!

03.12.2025 22:51 — 👍 1    🔁 0    💬 1    📌 0
Dorothy Bishop Prize 2026

Nominations for the UKRN Dorothy Bishop Prize 2026 have opened!

Named after @deevybee.bsky.social, the prize, first awarded in 2022, celebrates the contributions of early career researchers to research improvement.

Nominations close 18 January 2026.

#AcademicSky #Research

03.12.2025 12:55 — 👍 29    🔁 33    💬 0    📌 1
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Maximizing researcher–policymaker engagement in global public health - Nature Medicine Research does not always ‘speak for itself’; high-fidelity uptake of science into policy requires active engagement between researchers and policymakers. This Perspective offers tangible recommendatio...

Research doesn't translate into policy overnight - this Perspective explains what it takes with some useful case studies www.nature.com/articles/s41...

02.12.2025 09:26 — 👍 1    🔁 0    💬 0    📌 0
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🧡🇵🇸Join our next online Refugee Mental Health and Place seminar with Dr Abdullah Aldiwan on "Psychological Support for Palestinian Refugees Amid Genocide and Structural Injustice"
🗓️04 December 2025
⏲️16:00 - 17:30 GMT
Sign-up: www.kcl.ac.uk/events/psych...

30.11.2025 18:50 — 👍 4    🔁 5    💬 1    📌 0
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St Andrews 🤩

30.11.2025 16:29 — 👍 6    🔁 0    💬 0    📌 0
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Applications for the Genetics Society Summer Studentship Grants are open! If you’re an undergrad itching to dive into real research, this is your doorway into the lab.

More information here: genetics.org.uk/grants/summe...

27.11.2025 14:17 — 👍 5    🔁 12    💬 0    📌 1

Sign up for this workshop by @damiepak.bsky.social about mathematical simulations!

24.11.2025 13:29 — 👍 9    🔁 4    💬 0    📌 0
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What enables human language? A biocultural framework Explaining the origins of language is a key challenge in understanding ourselves as a species. We present an empirical framework that draws on synergies across fields to facilitate robust studies of l...

Origins of language, one of humanity’s most distinctive traits, may be best explained as a unique convergence of multiple capacities each with its own evolutionary history, involving intertwined roles of biology & culture. This framing can expand research horizons. A 🧵 on our @science.org paper.🧪1/n

23.11.2025 11:52 — 👍 201    🔁 87    💬 6    📌 9
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Proteome-wide model for human disease genetics Nature Genetics - popEVE is a proteome-wide deep generative model to identify and predict pathogenicity of missense mutations causing genetic disorders.

popEVE is out in Nature Genetics! 🎉
We built a proteome-wide model that combines cross-species and human population variation to rank missense variants by disease severity and help diagnose rare genetic disorders.
rdcu.be/eRu7K

24.11.2025 13:35 — 👍 49    🔁 19    💬 2    📌 1
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The missing heritability question is now (mostly) answered Not with a bang but with a whimper

I wrote a little bit about the "missing heritability" question and several recent studies that have brought it to a close. A short 🧵

21.11.2025 22:33 — 👍 349    🔁 170    💬 14    📌 21
Promotional graphic for free online webinars by the Atlas of Longitudinal Datasets. The main heading reads “We host Webinars!” followed by text inviting people to join free, online, international webinars. It mentions previous audiences such as researchers, students, and study teams. A call-to-action says “Contact us to set one up today!” with an email address: atlas.longitudinaldatasets@kcl.ac.uk. On the right, there are three icons with text: “Learn about the Atlas,” “Tailored sessions showing how our platform can help you,” and “Engage in a live demo on how to use the Atlas.” Features screenshots of the Atlas platform on desktop, laptop, and mobile. Logos for the Atlas of Longitudinal Datasets, Wellcome Trust, MQ Mental Health, and King’s College London are displayed.

Promotional graphic for free online webinars by the Atlas of Longitudinal Datasets. The main heading reads “We host Webinars!” followed by text inviting people to join free, online, international webinars. It mentions previous audiences such as researchers, students, and study teams. A call-to-action says “Contact us to set one up today!” with an email address: atlas.longitudinaldatasets@kcl.ac.uk. On the right, there are three icons with text: “Learn about the Atlas,” “Tailored sessions showing how our platform can help you,” and “Engage in a live demo on how to use the Atlas.” Features screenshots of the Atlas platform on desktop, laptop, and mobile. Logos for the Atlas of Longitudinal Datasets, Wellcome Trust, MQ Mental Health, and King’s College London are displayed.

🔍 Want to get the most out of the Atlas of Longitudinal Datasets?
We offer free online webinars with a tailored introduction and live demo to help you navigate the platform and make the most of its features.
📩 Interested? Email us to schedule a session: atlas.longitudinaldatasets@kcl.ac.uk

20.11.2025 11:11 — 👍 8    🔁 3    💬 1    📌 0

Many congratulations Sue @cogwild.bsky.social !

20.11.2025 21:40 — 👍 2    🔁 0    💬 1    📌 0
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PLEASE SHARE

🚨🚨 6-month RA position available at the Univ. of St Andrews to work with Sue Healy (@cogwild.bsky.social), Simone Meddle (@simonemeddle.bsky.social) and I on the behavioural neuroendocrinology of early reproduction in zebra finches.

tinyurl.com/577cx9tj

Deadline: 03/12/2025
⬇️

19.11.2025 18:23 — 👍 23    🔁 33    💬 1    📌 2
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Genomic Investigations of Spoken and Written Language Abilities: A Guide to Advances in Approaches, Technologies, and Discovery Purpose: The aim of this tutorial is to show how the rise of molecular technologies and analytical methods in human genetics yields exciting new ...

Advances in genomics are giving exciting new perspectives on biology of speech, language & reading. My latest peer-reviewed paper is a tutorial, guiding readers from different backgrounds through the history of the field, current state-of-the-art, & where we’re heading. A taster in this thread.🧪
1/n

17.11.2025 17:52 — 👍 55    🔁 30    💬 1    📌 2
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Autism, Microbiomes, & Mice Burying Marbles with Kevin Mitchell

Grateful to the Decoding the Gurus guys for having me on to discuss Autism, Microbiomes, & Mice Burying Marbles... @guruspod.bsky.social cc @statsepi.bsky.social @deevybee.bsky.social 😊 open.spotify.com/episode/01w8...

19.11.2025 09:32 — 👍 25    🔁 8    💬 1    📌 1

The Tartan Army is already the highlight of the World Cup 😀

18.11.2025 22:07 — 👍 3    🔁 0    💬 0    📌 0
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COME ON SCOTLAND! 🏴󠁧󠁢󠁳󠁣󠁴󠁿⚽️

Scotland is in the World Cup for the first time since 1998 after a historic 4-2 win against Denmark 🏆

18.11.2025 21:55 — 👍 131    🔁 35    💬 1    📌 8
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The right is more conservative than the left: a postnatal hypothesis of handedness based on mice Handedness is a fundamental behavioral trait in humans, with the majority exhibiting right-hand dominance. While its origins remain elusive, it is con…

🐭🐾 www.sciencedirect.com/science/arti...

18.11.2025 16:18 — 👍 1    🔁 0    💬 0    📌 0
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Now is the time for professionals nationwide to connect. There is so much more we can do to support the SEND crisis.
If you work for a local authority as an SpLD specialist please consider joining us. Please share widely
Interested? Drop me a line louise@louiseselbydyslexia.com

18.11.2025 09:36 — 👍 1    🔁 1    💬 0    📌 0
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#PhD opportunity: Join us in St Andrews to study brain health and healthy aging with data driven approaches in collaboration with brainsciences.scot as part of the EASTBIO DTP
www.findaphd.com/phds/project...

16.11.2025 10:27 — 👍 4    🔁 4    💬 0    📌 0
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Systematic morphological profiling of human and mouse miRNAs in 24M single cells MicroRNAs (miRNAs) are post-transcriptional regulators of gene expression whose contributions to cell biology remain underexplored. Here, we used Cell Painting to quantify the morphological effect of ...

New📢
Between molecular and human traits is a yawning gap: What do molecules do to single cells?
We tested *all* human or mouse miRNA mimics for their cell morphological effects on 5 cell lines.
To do so, we applied Cell Painting at the *single cell* level (100,000+ images).
doi.org/10.1101/2025...

16.11.2025 10:33 — 👍 15    🔁 8    💬 1    📌 0
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#PhD opportunity: Join us in St Andrews to study brain health and healthy aging with data driven approaches in collaboration with brainsciences.scot as part of the EASTBIO DTP
www.findaphd.com/phds/project...

16.11.2025 10:27 — 👍 4    🔁 4    💬 0    📌 0

Many congratulations!

14.11.2025 14:55 — 👍 1    🔁 0    💬 0    📌 0
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Congratulations @hilarycmartin.bsky.social from @sangerinstitute.bsky.social on being awarded the 2026 Balfour Lecture!

14.11.2025 12:35 — 👍 37    🔁 14    💬 5    📌 3
First page of Opinion piece: "Conceptual and methodological flaws undermine claims of a link between the gut microbiome and autism"

First page of Opinion piece: "Conceptual and methodological flaws undermine claims of a link between the gut microbiome and autism"

The link between the gut #microbiome and autism is not backed by science, researchers say.

Read the full opinion piece in @cp-neuron.bsky.social: spkl.io/63322AbxpA

@wiringthebrain.bsky.social, @statsepi.bsky.social, & @deevybee.bsky.social

13.11.2025 16:00 — 👍 232    🔁 116    💬 5    📌 30
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Conceptual and methodological flaws undermine claims of a link between the gut microbiome and autism Claims that the gut microbiome causally contributes to autism regularly appear in the scientific literature and popular press. Mitchell et al. critically examine influential studies underpinning these...

New paper with @statsepi.bsky.social and @deevybee.bsky.social in which we show there's really no evidence for a link between the gut microbiome and autism www.cell.com/neuron/fullt...

13.11.2025 16:10 — 👍 186    🔁 63    💬 6    📌 5
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Come to #Bonn next March and join the #BonnBrain Conference 2026! There’s still time left to register and submit your abstract:

🌍 https://bonnbrain.de/ @bonnbrainconf.bsky.social
⏰ March 23–25, 2026
📍 @dzne.science #DZNE

12.11.2025 04:19 — 👍 7    🔁 6    💬 0    📌 0

New preprint on the drain that for-profit publishers place on the scientific ecosystem. We also point out that, though it's often presented as a global problem, it's actually a Global North problem: there are parts of the world with strong diamond #OA non-profit alternatives arxiv.org/abs/2511.04820

11.11.2025 16:32 — 👍 37    🔁 19    💬 2    📌 1
Faculty Position in Computational Biology Applications are invited for an Assistant/ Associate Professorship in Computational Biology to commence on 1 April 2026 or shortly thereafter. This is a joint post between the Department of Applied

Come and join us here in Cambridge! Applications open for a new faculty position, for a researcher in computational and/or theoretical biology, based jointly in Genetics and Mathematics. Happy to answer questions about research, teaching and working here.

www.cam.ac.uk/jobs/faculty...

11.11.2025 21:05 — 👍 71    🔁 84    💬 0    📌 1
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The APOE4 allele, present in >20% of the population, is a significant risk marker for #Alzheimers. What if we could flip it to the protective APOE2 allele?
Encouraging results in the experimental model
www.nature.com/articles/s41...
www.nature.com/articles/s41...

11.11.2025 15:20 — 👍 107    🔁 20    💬 1    📌 1

@silparacchini is following 20 prominent accounts