#FragileNuclesome is back tomorrow! Join us to hear about exciting talks from:
- @au-ho-yu.bsky.social in @robklose.bsky.social's group about transcriptional control by SET1/MLL complexes
- @gcloner.bsky.social at @epicypher.bsky.social about the histone PTM landscape of the immune system
27.01.2026 18:24 β π 9 π 5 π¬ 0 π 0
Join @stirlingchurchman.bsky.social,
@moffittlab.bsky.social, @saramostafavi.bsky.social, me and all speakers for the 2026 CSHL meeting Systems Biology: Global Regulation of Gene Expression, March 11-14. Abstract deadline January 9! More infos and registration at meetings.cshl.edu/meetings.asp...
29.12.2025 09:00 β π 47 π 23 π¬ 1 π 1
Nice to hear from you, Kinga! I had a feeling I was missing someone - I did see you asking questions, one more fellow Oxford alumni π
18.07.2025 23:52 β π 1 π 0 π¬ 0 π 0
Also surprised but very pleased to see so many friendly faces from my time at Oxford @ilandavis.bsky.social, Sina Wittmann, Adam Cawte, @flavia-con.bsky.social
18.07.2025 21:27 β π 1 π 0 π¬ 0 π 0
Sad I couldnβt be there in person, but I really enjoyed listening to all the talks! What a great meeting with a unique focus on integrating single-molecule sequencing and imaging techniques. Excited to see how the field evolves!
18.07.2025 21:27 β π 6 π 1 π¬ 3 π 0
Happy to share this paper! We uncovered that good 5' splice sites protect against ZC3H4/Restrictor's promiscuous role, and that its role is to suppress elongation and indirectly cause termination. Looking forward to learning more about this protein in the future!
18.07.2025 08:33 β π 32 π 10 π¬ 3 π 1
βΌοΈLast chance to join us in person for #EMBLSingleMolecule! Attend talks, network, socialise, and experience the atmosphere on the campus π€©
π« Register by 3 Jun ππΌ http://s.embl.org/grg25-01-bl
π§¬RNA processing
π§¬Translation
π§¬Transcription & chromatin regulation
π§¬Method development
π§¬Theory
27.05.2025 13:45 β π 5 π 4 π¬ 0 π 2
Thrilled to see my postdoc work at Adelman Lab @hms-bcmp.bsky.social on Integrator(INT) now out @cp-cell.bsky.social. We found that INT deficiency allows immature+unlicensed RNAPII to precociously enter genes. This immature RNAPII can transcribe short genes but terminates prematurely in long genes:
14.04.2025 16:56 β π 51 π 14 π¬ 4 π 2
Our latest work now online in Cell:
Rewriting regulatory DNA to dissect and reprogram gene expression
Our new method (Variant-EFFECTS) uses high-throughput prime editing + flow sorting + sequencing to precisely measure effects of noncoding variants on gene expression
Thread π
17.04.2025 18:26 β π 116 π 28 π¬ 1 π 2
Oligo-LiveFISH is a high-resolution, reagent-based platform for studying 3D genome dynamics and their links to cellular processes in diverse cell types, including primary cells.
www.cell.com/cell/fulltex...
authors.elsevier.com/c/1kxK7L7PXu...
16.04.2025 23:39 β π 14 π 7 π¬ 1 π 0
Seattle DROP: Discover Research Opportunities for Postdocs
Interested in postdoc opportunities in Seattle, WA? Join us May 6th for Seattle DROP, a virtual event about biomedical research in Seattle. Hear from recruiting faculty, finding the right mentor and enjoy lunch on us via a delivery voucher within the US!
Registration: tinyurl.com/seattledrop25
16.04.2025 15:28 β π 48 π 50 π¬ 1 π 1
My group is hiring a new Postdoc to work on gene regulation and chromatin in Nematostella. Please RT!
For more information see here:
gahanlab.com
tinyurl.com/34xke35d
08.04.2025 12:09 β π 61 π 76 π¬ 1 π 5
Registration is now open for the 2025 Symposium on Physical Genomics, taking place Friday April 25 on Northwestern's Chicago campus - details at the link below. Planning on attending? Submit an abstract for the lunchtime poster session! #chromatin
physicalgenomics.northwestern.edu/news-events/...
17.03.2025 21:48 β π 4 π 4 π¬ 0 π 0
π£ #EMBLSingleMolecule is open for registrations!
Our aim is to catalyse the emergence of a new generation of mechanistic models of the regulation of genes across each steps of the central dogma. π§¬π
ππΌ s.embl.org/grg25-01-bl
π
15 β 18 July 2025
π Submit your abstract by 8 April!
15.01.2025 12:29 β π 21 π 18 π¬ 1 π 2
The importance of moving away from bulk! Occupancy of Pol II at promoters is dramatically different between fly and mouse cells! When looking single molecule! Proud of the team! @kasitc.bsky.social @molinalab.bsky.social doi.org/10.1038/s443...
02.04.2025 08:47 β π 115 π 37 π¬ 2 π 1
Behind the paper: βTemporal variability and cell mechanics control robustness in mammalian embryogenesisβ - the Node
The massive presence of disorder and variability challenges the traditional metaphor of the developmental process as a perfectly executed program leading
Could stochasticity play a role in ensuring robustness during development?
Read this 'Behind the paper' story from Bernat Corominas-Murtra about his work with Dimitri Fabreges, @virginieuhlmann.bsky.social, @ehannezo.bsky.social, Takashi Hiiragi @hubrechtinstitute.bsky.social & co:
#DevBio
16.12.2024 13:35 β π 25 π 7 π¬ 1 π 0
On the reading list
27.11.2024 09:54 β π 3 π 2 π¬ 0 π 0
Congratulations on this exciting story coming out! You kept us all in suspense :)
Can't wait to read it in detail π€
11.12.2024 22:21 β π 3 π 1 π¬ 1 π 0
Feel free to reach out if you have any questions!
16.12.2023 16:52 β π 0 π 0 π¬ 0 π 0
Summer Internship Program (SIP)
Are you an undergraduate student interested in doing a summer research project at the National Institutes of Health?
Please check out our summer research program π
www.training.nih.gov/research-tra...
16.12.2023 16:51 β π 10 π 6 π¬ 2 π 0
Scientist in North Carolina studying chromatin remodelers and transcription factors. @fnucleosome.bsky.social coorganizer
ORCID: 0000-0002-6256-144X
Views and posts are all my own
Postdoc at Biozentrum in Basel, and incoming group leader at the IMBA in Vienna.
How do single cells decide what to become? What to do? When? Where? In fact, how do humans?
https://www.oeaw.ac.at/imba/groups/daan-de-groot
Group leader @mpi-mg, Berlin
Chromatin tracing, epigenetics, development. Equity and advocacy in academia.
Scientist @arcinstitute
Exβ@stark_lab, @IMPvienna, @viennabiocenter
Chromatin Systems Biology
Assistant Professor at Center for Molecular Medicine - UMC Utrecht
Professor of Genomics at Oxford University. Interested in chromatin structure, gene regulation and genome editing
Postdoc at NIH/NCI, PHD at Hopkins
Associate Professor, University of Pennsylvania, Penn Epigenetics Institute
3D Genome structure and function
https://ericjoycelab.com/
https://pownall-lab.org | Sandler Fellow at UCSF | chromatin, transcription, microscopy (ChromExM), development ππ§¬π¬
Professor in Systems Biology & Genetics @EPFL, opinions my own; Single Cell Omics / Gene Regulation / Transcription Factor / Stem Cells / Regulatory Variation / ML / Imaging / Adipose Biology / Microfluidics
https://www.epfl.ch/labs/deplanckelab
Shy-guy-chris is interested in all sciency stuff, especially RNA biology and transcription. Currently working for Westicles at the University of Exeter.
Research Scientist at Institut Curie.
Postdoc at Tjian/Darzacq Lab, UC Berkeley.
PhD at Ellenberg Lab, EMBL Heidelberg.
Previously at Boutros Lab, Pines Lab, Stemmann Lab.
LinkedIn: nike-walther-836252b5
PhD student @Brockdorff lab
Assistant Prof at Utrecht University, studying the process of transcription elongation vs early termination. (she/her)
Transposons, chromatin, development. Group leader @ the MRC LMS in London and UKRI FLF. Mum of 2, she/her. Www.perchardelab.com
Postdoc in Anders Hansen lab at MIT. Previously PhD with Rob Klose. Interested in regulation of transcription and dynamics at single molecule level.
IMBA - Institute of Molecular Biotechnology: a leading research institute in Europe, focusing on functional genetics, RNA biology, and stem cell research.
Postdoc at Harvard OEB; brains, behavior, evolution, acoels. Previously: social evolution PhD at the Rockefeller
https://scholar.google.com/citations?user=z8ttnIMAAAAJ&hl=en
Assistant Professor @ Stanford Genetics & BASE Initiative. Mapping the regulatory code of the human genome to understand heart development and disease. www.engreitzlab.org