Michelle Percharde's Avatar

Michelle Percharde

@mpercharde.bsky.social

Transposons, chromatin, development. Group leader @ the MRC LMS in London and UKRI FLF. Mum of 2, she/her. Www.perchardelab.com

729 Followers  |  573 Following  |  63 Posts  |  Joined: 13.11.2024  |  1.8212

Latest posts by mpercharde.bsky.social on Bluesky

Thank you Rob! πŸ‡¬πŸ‡§

02.12.2025 22:12 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Thank you Deborah!

02.12.2025 22:12 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Thanks Antoine!

02.12.2025 20:55 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Thanks Abby!

02.12.2025 20:53 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Thank you!

02.12.2025 20:53 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Thank you for your support Lila!

02.12.2025 16:04 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

πŸ₯°πŸ₯°πŸ₯° thank you. Looking forward to more TEtime together ;)

02.12.2025 16:03 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Very excited to be part of this prestigious programme, thank you @embo.org !

02.12.2025 14:15 β€” πŸ‘ 27    πŸ” 3    πŸ’¬ 4    πŸ“Œ 0
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Congratulations to the new cohort of 28 EMBO Young Investigators! They are joining an international network of more than 800 life scientists – Welcome!

Read the press release here:
https://www.embo.org/press-releases/twenty-eight-group-leaders-become-embo-young-investigators/

02.12.2025 13:06 β€” πŸ‘ 132    πŸ” 31    πŸ’¬ 5    πŸ“Œ 31

🚨Post open in our lab! Come work on some cool themes involving metabolism, chromatin, early development πŸ€“. Pls RT

27.11.2025 14:26 β€” πŸ‘ 5    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
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MRC Postdoctoral Research Scientists x 6 - MRC Laboratory of Medical Sciences Team Science Project

πŸ“£ We’re hiring 6 new Team Science postdocs!

Our Team Science approach brings together interdisciplinary researchers to tackle questions no single field can solve alone.

Find out more and download our brochure below

20.11.2025 13:43 β€” πŸ‘ 12    πŸ” 14    πŸ’¬ 0    πŸ“Œ 3

#TEsky

16.11.2025 18:44 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Register now for our one-day symposium at the MRC Laboratory of Medical Sciences on environmental and metabolic control of early development on 4 December 2025!

Spaces are limited, register here: www.symposia.org.uk/courses/stem...

14.11.2025 16:56 β€” πŸ‘ 7    πŸ” 6    πŸ’¬ 0    πŸ“Œ 0

Spaces filling up for our @bsdb.bsky.social GRT symposium @mrc-lms.bsky.social on environment, metabolism and stem cell development 4th Dec 2025! Updated poster with talk titles below. Register here: www.symposia.org.uk/courses/stem...

Looking forward to seeing you there!

10.11.2025 13:54 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Studentships and PhD training We have two core PhD programmes - traditional and transdisciplinary. Our PhD students are registered with Imperial and are embedded in our dedicated research facility.

We are launching 11 new #PhD opportunities today!

If you would like to contribute to the research at the LMS apply today!

#medicalscience #lifescience

09.10.2025 13:58 β€” πŸ‘ 5    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0

We have a new PhD studentship in the lab on the immunogenic roles of transposable elements in paediatric acute myeloid leukaemia! Come and work with us! www.colcc.ac.uk/2026-cyp-phd...

02.10.2025 18:51 β€” πŸ‘ 8    πŸ” 12    πŸ’¬ 0    πŸ“Œ 0
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World’s first AI-designed viruses a step towards AI-generated life Scientists used AI to write coherent viral genomes, using them to synthesize bacteriophages capable of killing resistant strains of bacteria.

World’s first AI-designed viruses a step towards AI-generated life. #Nature

Scientists used AI to write coherent viral genomes, using them to synthesize bacteriophages capable of killing resistant strains of bacteria.

www.nature.com/articles/d41...

20.09.2025 17:46 β€” πŸ‘ 13    πŸ” 7    πŸ’¬ 1    πŸ“Œ 1
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Head of Bioinformatics - MRC Laboratory of Medical Sciences We are recruiting for a Head of Bioinformatics to lead our Bioinformatics facility

Come be our head of bioinformatics at @mrc-lms.bsky.social !

Our bioinformatics team are closely involved with lots of interesting science and we love working with them. Topics inc. development, cancer, metabolism, aging, TEs (my favourite of course 😜) #TEsky lms.mrc.ac.uk/work/vacanci...

19.09.2025 08:25 β€” πŸ‘ 7    πŸ” 6    πŸ’¬ 0    πŸ“Œ 0

Great to see this out in final form. Congrats Abby!

14.08.2025 22:01 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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it appears your low-hanging-fruit phd project wasn't so risk free after all, mr. bond

31.07.2025 14:50 β€” πŸ‘ 83    πŸ” 3    πŸ’¬ 1    πŸ“Œ 1

Join the #LMS! Our institute is advertising for junior #GroupLeader positions in #Physiology and #Metabolism. Closing date for applications: August 31st!

27.07.2025 09:37 β€” πŸ‘ 7    πŸ” 6    πŸ’¬ 0    πŸ“Œ 0
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Study reveals the hidden benefits of weight loss on fat tissue Scientists from the MRC Laboratory of Medical Sciences (LMS) and Imperial College London have produced the first detailed characterisation of the changes that weight loss causes in human fat tissue by...

A new study, published today in Nature, reveals the hidden benefits of weight loss on fat tissue.

A better understanding of how weight loss leads to health improvements at a molecular level could help inform the development of therapies for diseases such as type 2 diabetes in the future.

09.07.2025 15:19 β€” πŸ‘ 17    πŸ” 9    πŸ’¬ 1    πŸ“Œ 5
Poster for Genesis Research Trust / BSDB symposium on metabolism and stem cells

Poster for Genesis Research Trust / BSDB symposium on metabolism and stem cells

🚨Symposium alert! 🚨 Next edition of our biennial stem cell symposium is 4th Dec 2025 - focus on metabolism and development. Sponsored by @bsdb.bsky.social. Great lineup of speakers, hosted @mrc-lms.bsky.social in London. Registration is open.

www.symposia.org.uk/courses/stem...

08.07.2025 11:00 β€” πŸ‘ 16    πŸ” 11    πŸ’¬ 0    πŸ“Œ 1
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Paper alert! I am really pleased to share the final version of the work led by Irène Amblard in the team on a regulatory switch controlling Cdx2 expression during posterior body development! #regulatorylogic #devbio @mrc-lms.bsky.social @imperialmed.bsky.social

27.06.2025 15:07 β€” πŸ‘ 111    πŸ” 37    πŸ’¬ 18    πŸ“Œ 3
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MRC Postdoctoral Research Scientist - MRC Laboratory of Medical Sciences The MRC Laboratory of Medical Sciences (LMS) is a biomedical research institute where scientists and clinicians collaborate to advance the understanding of biology and its application to medicine. LMS...

The Chromatin And Development lab are hiring a postdoc!

Come join us; we are a happy and hard working team @mrc-lms.bsky.social in London UK. Projects span the intersection of chromatin and transposon biology in dev't and disease. Email/DM for more info. Pls RT!

lms.mrc.ac.uk/work/vacanci...

26.06.2025 15:18 β€” πŸ‘ 30    πŸ” 31    πŸ’¬ 0    πŸ“Œ 1

This should almost have an international reach: about what the rainbow flag means for queer people, by Oslo Pride.

28.05.2025 18:55 β€” πŸ‘ 41    πŸ” 15    πŸ’¬ 1    πŸ“Œ 0

LTRs as dogs…can be friendly, quite helpful at times. LINEs as cats? Also pretty nice in some cases, but also will get angry and scratch out your eyes. Hmm #TEsky πŸ€”

26.05.2025 18:20 β€” πŸ‘ 9    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

I love the concept of domesticated transposable elements. I like that my genome has its little viral pets to feed nucleic acids and take out for transcriptional walkies. 🧬

26.05.2025 17:41 β€” πŸ‘ 49    πŸ” 15    πŸ’¬ 4    πŸ“Œ 1

I feel like the clusters of pistachios (?) are significant here hmmm

20.05.2025 07:00 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Figure 1 Nucleolar structure and rRNA gene organisation.

Figure 1 Nucleolar structure and rRNA gene organisation.

In this Review, @bryonyleeke.bsky.social, Imke Staffhorst and @mpercharde.bsky.social @mrc-lms.bsky.social explore roles of the nucleolus in mammalian development, focusing on genome organisation and chromatin regulation:
doi.org/10.1242/dev....

16.05.2025 08:51 β€” πŸ‘ 6    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0

@mpercharde is following 20 prominent accounts