Siobhán McClean's Avatar

Siobhán McClean

@siobhanmcclean.bsky.social

Professor at UCD; Scientist➡️Infection; host-pathogen interactions; bacterial adaptation; Vaccines;vaccine advocacy; mum to 3; love walking in mountains #AndICycle #Inclusion; Sí/í

909 Followers  |  897 Following  |  58 Posts  |  Joined: 30.11.2023  |  1.9095

Latest posts by siobhanmcclean.bsky.social on Bluesky

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a man is juggling soccer balls in front of a sign that says " ортой жизни " on it Alt: Man juggling soccer balls while moving on a hoverboard

Me trying to progress a backlog of several near-complete papers towards journal submission before I go on leave next month. 😅 #AcademicLife

11.07.2025 16:21 — 👍 4    🔁 0    💬 0    📌 0

The speakers may be amazing. But why are there only 2 women out of 15 speakers?
I thought we had moved beyond that.

27.06.2025 23:19 — 👍 1    🔁 0    💬 1    📌 0
Title Slide reads “Visualising how HIV-1 signalling remodels nuclear pores to license infection” with an image of a CD4+ T cell Nuclear pore behind.

Title Slide reads “Visualising how HIV-1 signalling remodels nuclear pores to license infection” with an image of a CD4+ T cell Nuclear pore behind.

🧪Great talk by @mattvxwhelan.bsky.social in the @ucddublin.bsky.social Conway CLASS lecture.
Amazing images of HIV / Nuclear interactions

10.06.2025 23:08 — 👍 5    🔁 1    💬 1    📌 1
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European Citizens' Initiative Give your support !

EU citizens' initiative to ban conversion practices targeting LGBTQ+ people needs to reach:
—minimum thresholds in 7 countries: ✅
—1 million total signatures: ⏳ (currently 875k)

Deadline is today, Friday 17 May 2025. Sign it, share it, get it over the line:

eci.ec.europa.eu/043/public

16.05.2025 10:26 — 👍 0    🔁 0    💬 0    📌 0
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Opinion | I Came to Study Aging. Now I’m Trapped in ICE Detention.

🧪 Russian-born scientist Kseniia Petrova was conducting anti-aging research at Harvard Medical School but is in detention since February.
Her hearing is tomorrow.

www.nytimes.com/2025/05/13/o...

13.05.2025 22:35 — 👍 36    🔁 22    💬 0    📌 1
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The ‘Hole-in-the-Ground Girl’ Leanne Bulger recently found a new hole in the forest floor on the west end of Fairbanks. Into it, she poked a long plastic pipe.

🧪 For some lighter science news here's an intriguing story from the thawing north. I first encountered it when Leanne presented a poster with her excellent undergraduate research at a student symposium a few months ago. Now science writer Ned Rozell wrote this: www.uaf.edu/news/the-hol...

04.05.2025 03:42 — 👍 64    🔁 23    💬 4    📌 5
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Genomic epidemiology and phylodynamics of Acinetobacter baumannii bloodstream isolates in China - Nature Communications The genomic epidemiology of Acinetobacter baumannii, which is rising in virulence and multidrug resistance, was explored. This study examined bloodstream infection isolates from Chinese patients in 20...

Interesting paper

Genomic epidemiology and phylodynamics of Acinetobacter baumannii bloodstream isolates in China

'A. baumannii is evolving from a low-virulence, multidrug-resistant pathogen to a more virulent one'

www.nature.com/articles/s41...

17.04.2025 08:58 — 👍 19    🔁 8    💬 0    📌 0

Hey BlueSky, I need your help. If you're in STEM & from a lower socioeconomic background, what barriers did you face in HS, college, grad school, or faculty roles? I want your stories—& any lit you know of. Let’s talk about the real cost of doing science. #AcademicSky #SciOutreach

11.04.2025 20:29 — 👍 16    🔁 10    💬 8    📌 2

reviewers for their thorough and insightful reviews.
This review has been in writing for a while and it’s great to finally share the accepted publication
@ucd-sbbs.bsky.social
@ucddublin.bsky.social

03.05.2025 08:37 — 👍 0    🔁 0    💬 0    📌 0

also happen in response to hypoxia. We highlight how exposure of these bugs to hypoxia in the environment can predispose them to colonisation of hypoxic niches, arming them with mechanisms than enable their evasion of the immune system and establish chronic infections. We’re very grateful to the …

03.05.2025 08:37 — 👍 0    🔁 0    💬 1    📌 0

We discuss 3 species that colonise the lungs of people with CF: P.aeruginosa, B.cepacia complex & M.abscessus and draw parallels btw their 3 oxygen-sensing two-component systems: BfiSR, FixLJ, and DosRS. Many adaptations that these bugs undergo during chronic infection- AbxR, protease & motility …

03.05.2025 08:37 — 👍 0    🔁 0    💬 1    📌 0

🧪Delighted our review on the impact of Hypoxia on Chronic infection in Cystic fibrosis is published online FEMS MicroRev @Ciaranjcarey.bsky.social, @NiamhDuggan.bsky.social & @jdrabinska.bsky.social should be proud of it 🙌
🙏 to @researchireland.bsky.social

track.smtpsendmail.com/9032119/c?p=...

03.05.2025 08:37 — 👍 13    🔁 3    💬 1    📌 0

This is the kind of stuff you see in antivaxx Facebook groups: “can anyone share data showing that vaccines are bad?” Except now it’s coming from atop the entire US health and biomedical science apparatus. There is more data for vaccines than almost anything ever and it doesn’t show vaccines are bad

04.04.2025 23:11 — 👍 1293    🔁 365    💬 23    📌 3
Talk title Three novel effective vaccine antigens against Klebsiella pneumoniae infection

Talk title Three novel effective vaccine antigens against Klebsiella pneumoniae infection

Post image

Great talk by Yueran Hou in our lab @ucd-sbbs.bsky.social on her #klebsiella pneumoniae vaccine candidates at the #Microbiology Society conference in Liverpool
@ucddublin.bsky.social 🧪

02.04.2025 11:45 — 👍 7    🔁 0    💬 3    📌 0
Speaker on podium with title slide

Speaker on podium with title slide

Lovely talk @aaroncurtismicro.bsky.social at Microbiology Society annual meeting on your ex Vivo aspergillus fumigatus infection model. Very interesting proteomics analysis
@maynoothuniversity.ie 🧪🧪

02.04.2025 11:08 — 👍 1    🔁 0    💬 2    📌 0
Image description: A woman with pink and purple hair with green and blue eyeliner holds a copy of the book THE ELEMENTS OF MARIE CURIE: HOW THE GLOW OF RADIUM LIT A PATH FOR WOMEN IN SCIENCE by Dava Sobel.

Image description: A woman with pink and purple hair with green and blue eyeliner holds a copy of the book THE ELEMENTS OF MARIE CURIE: HOW THE GLOW OF RADIUM LIT A PATH FOR WOMEN IN SCIENCE by Dava Sobel.

Image description: A woman with pink and purple hair with green and blue eyeliner holds a copy of the book THE ELEMENTS OF MARIE CURIE: HOW THE GLOW OF RADIUM LIT A PATH FOR WOMEN IN SCIENCE by Dava Sobel.

Image description: A woman with pink and purple hair with green and blue eyeliner holds a copy of the book THE ELEMENTS OF MARIE CURIE: HOW THE GLOW OF RADIUM LIT A PATH FOR WOMEN IN SCIENCE by Dava Sobel.

A #booklewk for THE ELEMENTS OF MARIE CURIE: HOW THE GLOW OF RADIUM LIT A PATH FOR WOMEN IN SCIENCE by Dava Sobel

CW: Sexism, Medical content, WWI, death from cancer, exposure to radium, anemia.

This book is a must-read especially for my #chemsky #booksky friends!

Here are my thoughts (thread 🧵):

30.03.2025 21:26 — 👍 55    🔁 9    💬 5    📌 0
Rainfall radar of Ireland showing rain everywhere except a very smooth, semi circle showing a rain free region all around the Dublin area.

Rainfall radar of Ireland showing rain everywhere except a very smooth, semi circle showing a rain free region all around the Dublin area.

Unusual rainfall radar map for Dublin with a very smooth contour around the city. Is this a real atmospheric effect or a digital artefact? #MetEireann

29.03.2025 13:43 — 👍 3    🔁 0    💬 3    📌 0
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Monosaccharide-Based Synthetic TLR4 Agonist Enhances Vaccine Efficacy against Pseudomonas aeruginosa Challenge Vaccine adjuvants are critical to improve the immunogenicity, efficacy, and durability of vaccines; however, their development has lagged behind that of vaccine antigens. Monophosphoryl lipid A (MPLA)...

New paper #BactiVax ITN. Maite Sainz & others in our lab show TLR4 agonists (F.peri lab) are effective adjuvants in a P.aeruginosa vaccine, enhancing protection in a pneumonia model
New vaccines are badly needed to prevent P aeruginosa infection 🧪
@ucd-sbbs.bsky.social
pubs.acs.org/doi/10.1021/...

29.03.2025 11:56 — 👍 2    🔁 0    💬 0    📌 0
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Orange County Couple Deported to Colombia After 35 Years in U.S. Laguna Niguel residents with no criminal record were detained during routine immigration check-in

"The deportation left three adult daughters—Jessica, Stephanie, and 23-year-old Gabby—plus a young grandson behind in the United States."

This is all beyond sickening.

22.03.2025 00:26 — 👍 53    🔁 19    💬 4    📌 2

Terrible.

Measles is so easily prevented with a the vaccine
😢

22.03.2025 00:35 — 👍 1    🔁 0    💬 0    📌 0
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Repurposing BCG for Bladder Cancer: How the TB Vaccine Changed the Face of Cancer Treatments | Medical News Bulletin The BCG vaccine, used to treat tuberculosis, has been repurposed for cancer, and we're here to explain how.

RFK jr wants you to think vaccines are dangerous. It's not clear why. But what
is clear is that Vaccines save lives. Some vaccines do more than just stave off
infections, this one moonlights as a cancer treatment- 🤯
buff.ly/4dEdvz1 #TB #vaccines #cancer #lovescience 🧪

20.02.2025 19:50 — 👍 47    🔁 10    💬 1    📌 0

Sadly this increase in in measles cases was inevitable with the anti-vax narrative being pushed by RFK and his ilk.
Children experience life-long complications from measles and some will die.
In 2025, kids will die from a vaccine preventable illness as a result of people’s arrogance and ignorance

18.02.2025 20:55 — 👍 4    🔁 0    💬 0    📌 0

🧪

18.02.2025 20:48 — 👍 8    🔁 0    💬 1    📌 0

How was this “pioneering ocular gene therapy” developed if not through research and innovation and dedication of 1000s of people who work in research.. Yet, this in not valued in Ireland.. for example, we have this; www.irishtimes.com/ireland/educ...

18.02.2025 20:35 — 👍 6    🔁 3    💬 0    📌 1
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Wars are fuelling antibiotic-resistant infections, threatening global health crisis Governments, pharmaceutical companies and international organisations must co-ordinate a response before it’s too late

The global antibiotic resistance crisis was already very grim, but wars are further exacerbating the issue
We need better treatments and #vaccines to prevent antibiotic resistant bacterial infections and we need them now.

www.irishtimes.com/science/2025...

13.02.2025 08:15 — 👍 3    🔁 0    💬 0    📌 0

Absolutely- Yalla !

01.02.2025 15:39 — 👍 2    🔁 0    💬 0    📌 0
Incredible temple entrance facade cut into the red/pink coloured sandstone mountain. Two levels: lower level insists on 6 Columns 
and a massive doorway.

Incredible temple entrance facade cut into the red/pink coloured sandstone mountain. Two levels: lower level insists on 6 Columns and a massive doorway.

Large tomb structures cut into the pink sandstone cliff. Lower door way above which there are a side view of steps leading upwards - all carved into the rock.

Large tomb structures cut into the pink sandstone cliff. Lower door way above which there are a side view of steps leading upwards - all carved into the rock.

Several arches carved into the pink rock, over which is another huge facade tomb structure.

Several arches carved into the pink rock, over which is another huge facade tomb structure.

I’ve had the wonderful privilege of visiting Petra in Jordan today in advance of the Women in STEM events tomorrow commemorating St Brigid’s day. We almost had the place to ourselves. Incredible place. It’s such a pity that Jordanian tourism has reduced to only 10% of what it was in recent years.

01.02.2025 15:34 — 👍 7    🔁 0    💬 2    📌 0

🧪

30.01.2025 14:30 — 👍 0    🔁 0    💬 0    📌 0
Post image Post image

We’d a great meeting of our @HEA-funded #NSRP @AIVRT All-island Vaccine Research &Training network @ucddublin.bsky.social Conway Institute Lots of progress made and we’ve planned some exciting collaborative studies 4 nxt 2 years
@annemoore.bsky.social
@valvanom.bsky.social
@nouranrezk.bsky.social

30.01.2025 14:21 — 👍 1    🔁 3    💬 0    📌 2
Post image Post image

We’d a great meeting of our @HEA-funded #NSRP @AIVRT All-island Vaccine Research &Training network @ucddublin.bsky.social Conway Institute Lots of progress made and we’ve planned some exciting collaborative studies 4 nxt 2 years
@annemoore.bsky.social
@valvanom.bsky.social
@nouranrezk.bsky.social

30.01.2025 14:21 — 👍 1    🔁 3    💬 0    📌 2

@siobhanmcclean is following 19 prominent accounts