Dr Laura Nolan

My lab @scelse.bsky.social NTU is growing! Fun evening out with the team, I'm so fortunate to work with such a great group of scientists!

Illustration of a leftover fried rice recipe. The recipe instructions are written above a drawing of a plate filled with fried rice, vegetables, and a fork. The steps include chopping ingredients, sautéing garlic or onion, stir-frying veggies and protein, adding rice, and tossing with sauce. The bottom of the image features the phrase "Bon Appétit!" and a small EU flag icon.

Today is International Day of Awareness of Food Loss and Waste. Millions of tonnes of food are wasted in the EU each year, impacting the planet and our future.

We cannot afford to waste it ↓

Nice to see a follow up story on @drlauranolan.bsky.social Pseudomonas aeruginosa T6SS toxin Tse8

Great to start this research @quadraminstitute.bsky.social with @cwhitch.bsky.social @science-bear.bsky.social @alisonmather.bsky.social @haideralkhanaq.bsky.social, Samuel Bloomfield, Greg Wickham, Ryan Sweet. Excited to continue food chain biofilm research in my lab @scelse.bsky.social!

Thrilled to see my first publication on food chain biofilms out! Check out the super cool biofilms Pseudomonas makes on food surfaces and the contribution of these to food spoilage. We're continuing to work in this space to find novel ways to extend food shelf life and reduce food waste! 🧫🧪

If you don’t get your child vaccinated against measles, it can put them at a high risk of this serious infection, which can lead to severe complications or even death. Make sure your child’s measles vaccination is up to date.

If you don’t get your child vaccinated against #measles, it can put them at a high risk of this serious infection, which can lead to severe complications or even death.

Make sure your child’s measles vaccination is up to date.

New capabilities! SCELSE has installed a new isothermal microcalorimetry system (Symcel CalScreener) to track microbial metabolism in real-time — including responses to antibiotics, phage; and in biofilms and during transitions to alternate lifestyles. Pix (R): Prof Whitchurch - cwhitch.bsky.social

Throwing a spotlight on genomic dark matter: the power and potential of transposon-insertion sequencing Linking genotype to phenotype is a central goal in biology. In the microbiological field, transposon mutagenesis is a technique that has been widely used since the 1970’s to facilitate this connection...

Thank you so much to @drlauranolan.bsky.social and Mark Webber for putting this JBC review together. Such exciting days that bacterial genetics and transposon mutagenesis can push the boundaries on discovering novel gene function and put more light on the genomic dark matter. See at rb.gy/ovefri

Only a few weeks left to apply for this PhD position in my lab at SCELSE @scelse.bsky.social. Come and join us in lovely Singapore to work on #biofilms #microbiomes #foodchain 🧪🧫

Unravelling the regulation of programmed cell death in Pseudomonas aeruginosa biofilms One 4-year PhD Studentship in Professor Cynthia Whitchurch’s lab at the Singapore Centre for Environmental Life Sciences Engineering (SCELSE) at Nanyang Technological University (NTU), Singapore – starting January 2026. The studentship will be funded for 4 years which includes tuition fees and a bursary. Students can be from Singapore or overseas. Project summary Programmed cell death (PCD) pathways are genetically encoded programmes that lead to cell suicide. Whist it seems counter-intuitive that single-celled bacteria would maintain cell suicide pathways, PCD is beneficial to multicellular bacterial communities. We have determined that Pseudomonas aeruginosa has 3 PCD pathways that intersect to enable explosive cell lysis for the release of extracellular DNA and other matrix components required for biofilm formation. This project aims to understand how these complex pathways that lead to PCD in P. aeruginosa are regulated. The project will use a range of cutting-edge approaches including molecular microbiology, transcriptomics, bioinformatics, AI and advanced microscopy. Requirements Applications are invited from candidates with a Bachelors degree with Honours (2nd class upper division) or equivalent, or Masters degree in Microbiology, Biochemistry, Biomedical Sciences or a related discipline. Additionally, experience in molecular microbiology, microscopy and microbial genomics would be advantageous. However, in the absence of this additional experience the applicant should be keen to learn relevant skills in these areas. Note that the following will be required of the candidate that is selected for this studentship (the application has to be submitted by the July 31st 2025): 1. Valid TOEFL/IELTS/GRE/GMAT/GATE scores (A valid GRE/GMAT score is required for applicants who are not graduates of the Autonomous Universities in Singapore, unless there is specific requirement state…

I have an exciting opportunity to join my research team in Singapore @scelse.bsky.social as a PhD student to explore programmed cell death in biofilms. See below for more information and please share widely!

Here's an exciting opportunity for a PhD studentship to study #biofilms and #microbiomes in the food chain with @drlauranolan.bsky.social at SCELSE @scelse.bsky.social.
I highly recommend!
🧪🧫

My lab at SCELSE, NTU, Singapore, is recruiting a PhD student to study food chain biofilms! The PhD will commence in January 2026 and tuition and stipend is provided for 4 years. Singaporean and international applicants welcome. See attached for more details. Please share widely!

Siderophore synthetase-receptor gene coevolution reveals habitat- and pathogen-specific bacterial iron interaction networks Coevolving siderophore genes shape bacterial iron networks, unveiling the complexity of cheating across habitats and lifestyles.

We derive iron-siderophore interaction networks among Pseudomonas strains from sequencing data. One key insight: natural strains form dense networks, whereas pathogens are loners. With @frimanscience.bsky.social @zhiyuanli.bsky.social & Nanjing colleagues
www.science.org/doi/10.1126/...

Personalized bacteriophage therapy outcomes for 100 consecutive cases: a multicentre, multinational, retrospective observational study - Nature Microbiology Analysis of 100 consecutive personalized bacteriophage therapy cases supports the use of personalized and sometimes pre-adapted, bacteriophage preparations, often in combination with antibiotics.

Noncomparative and heterogeneous, but so refreshing to see something larger than a small report or case study confirming that bacteriophage therapy is safe and, in many cases, effective.

#IDSky
#Phage

www.nature.com/articles/s41...

The Institut Pasteur is recruiting group leaders!
Pasteur is an absolute incredible environment to start your lab. Surrounded by so many great scientists, in the beautiful city of Paris.
Come eat 🥐 and conduct awesome science.
Contact me if you want info !

research.pasteur.fr/en/call/call...

Structure of the Pseudomonas aeruginosa PAO1 Type IV pilus
Finally out in PLOS Pathogens. Congrats Hannah Ochner and co-authors. @mrclmb.bsky.social

journals.plos.org/plospathogen...

Great and busy times at @fillouxlab.bsky.social a few years back 😅. @lukeallsopp.bsky.social, @drlauranolan.bsky.social and I constructed a few TraDIS libraries to answer T6SS questions. Still remember the soundtrack of these days: Barry White 😂😂😂 over and over so the experiments were repetitive

#Microsky #Science #microbiomesky

Research Fellow (Food Chain Biofilm Biology) The Singapore Centre for Environmental Life Sciences Engineering (SCELSE) is a unique interdisciplinary Research Centre of Excellence (RCE), funded by National Research Foundation, Ministry of Educati...

I'm recruiting a Research Fellow/Postdoc to join my team at #SCELSE to work on food chain biofilms to find new ways to extend food shelf life and reduce food waste. If you have skills in #microbiology and #biofilms apply via Workday: tinyurl.com/3468xm34 or MCF: tinyurl.com/5fyy6hdd. Share widely!

PhD studentship: Staphylococcus aureus interactions in cystic fibrosis polymicrobial infections at Newcastle University on FindAPhD.com PhD Project - PhD studentship: Staphylococcus aureus interactions in cystic fibrosis polymicrobial infections at Newcastle University, listed on FindAPhD.com

Funded PhD available in my lab. Pls repost! www.findaphd.com/phds/project...

Research Fellow (eDNA in Biofilms) The Singapore Centre for Environmental Life Sciences Engineering (SCELSE) is a unique interdisciplinary Research Centre of Excellence (RCE), funded by National Research Foundation, Ministry of Educati...

I'm recruiting! I'm looking for a motivated postdoctoral scientist to join my new team at SCELSE in Singapore. The role will explore various aspects of how #eDNA is produced and utilised in #Pseudomonas aeruginosa biofilms.

#Microsky #phagesky #Science

ntu.wd3.myworkdayjobs.com/Careers/job/...

For my first post on BlueSky I thought about to share some of the fun we had at the SCELSE year end party. Many thanks to Allen Chow and all organisers for giving us some relax and enjoyable timer after a very intense 2024.

It was a really fun evening! Has been a fantastic first few months at SCELSE and in Singapore, very happy to be here!! 🏝️ ☀️ 🧪 🧫 🧬

Microbiome research according to Gary Borisy

Join us!
4 Assistant/ Associate Professor posts available at University of Warwick School of Life Sciences, 2 in Host-Pathogen interactions and 2 in Plant Sciences:
warwick-careers.tal.net/vx/lang-en-G...

warwick-careers.tal.net/vx/lang-en-G...

#microsky

Fully Funded #PhD Position with Prof Andy Roe, Dr Rebecca McHugh and me as part of NorthWestBio bbsrc DTP

INS AND OUTS OF DISARMING TYPE 3 SECRETION – UNDERSTANDING RESISTANCE TO AURODOX

www.gla.ac.uk/postgraduate... please repost

Twwet screenshot from an old white man, implicating that you are only suited for research if you are willing to sacrifuce your weekends for it. Toxic crap.

Another charity funder featuring an old white man, this one spouting ableist crap that you are only suited for research if you are willing to sacrifice your weekends for it.

Why do charities not learn? Why are such people given a platform?

I am sure he thinks he means well, but it is oh so toxic.

Career opportunities post.

The University of Dundee is looking to hire group leaders. Up to 45 Principal Investigators across all career stages (tenure-track to Professorial) are available.

Sunniest city in Scotland, lots of outdoors and #proteomics

Details: buff.ly/3sQcVvJ

I’ve made it over here, even if slightly late! Looking forward to seeing what’s happening here 😊 #MicroSky