Kyler Crawford

CXCL12 Derived From ACKR1+ Intraplaque Neovessels Mediates CD8+ T Cell Recruitment in Human Atherosclerosis - PubMed CXCL12 Derived From ACKR1+ Intraplaque Neovessels Mediates CD8+ T Cell Recruitment in Human Atherosclerosis

pubmed.ncbi.nlm.nih.gov/39993040/ New publication opening up understanding about inflammation, health, genetics related to ACKR1/Duffy

AlphaBridge: tools for the analysis of predicted macromolecular complexes Artificial intelligence (AI)-powered protein structure prediction methods have revolutionised how life scientists explore macromolecular function. Using AI to predict the structure of macromolecular c...

🚀 Excited to share my first preprint on bioRxiv

www.biorxiv.org/content/10.1...

AlphaBridge simplifies protein structure predictions for experts and novices by combining complex analysis with visual representations and interactive tools in one user-friendly platform.

Icy river in the foreground of a bridge within a city of varied types of buildings

Milwaukee, 2024

Welcome! You are invited to join a webinar: Global Health Watch: Marburg Virus. After registering, you will receive a confirmation email about joining the webinar. Join us for a collaborative webinar hosted by IDSA and ESCMID to explore critical updates on the Marburg Virus. This session will feature expert insights into the clinical aspects of the virus, on-the...

Join us for a joint @idsainfo.bsky.social webinar exploring critical updates on the Marburg Virus outbreak. This session will feature expert insights into the clinical aspects, on-the-ground experiences from outbreak response, and future preparedness strategies.

ow.ly/Egv850UkS59
#IDSky #Clinmicro

It begins!

This is a stunning paper on how GAGs are pro survival factors for dormant tumor cells, I think this also gives us clues that GAGs are key cell survival components in normal biology! www.cell.com/cancer-cell/...

Fluorescent Tags Are Basically Never Silent

Fluorescently labeled proteins are essential to research. But we should never forget how messed-up their behavior can be. An example from condensates:

Power with touch

Resourceful, impressive!

Excellent staining makes the vessels really stand out, check out this capture from Nikola Sobczak with @johanduchene.bsky.social at IPEK/LMU Munich. Easy to imagine how different cell-mediated responses at the omentum would be contributors for acute symptoms or influence outcomes of surgery etc.

Zoom in on milky spots!

During peritonitis, leukocytes enter the peritoneal cavity through vessels in milky spots of the omentum.

Here, vessels (green) densely surround a milky spot (blue).

Picture by Nikola Sobczak (PhD student).

#FluorescenceFriday #ImmunoSky 🧪

Collage of SARS-CoV-2 structures released in the PDB this year

20 new SARS-CoV-2 structures this week, 716 this year (shown), for 4626 total available in the PDB.
Explore them all at rcsb.org/covid19

Breeze on a Fall day out with Ellie