Not all chemokine signaling is about cell migration!
In mouse erythroblasts, CXCL12-bound CXCR4 enters the nucleus to control gene transcription, trigger calcium bursts, and drive red blood cell formationβespecially enucleation.
π science.org/doi/10.1126/scβ¦
#chemokine #CXCR4
21.06.2025 17:11 β π 22 π 13 π¬ 3 π 0
Inflammatory chemokine receptors CCR1, CCR2, CCR3 and CCR5 are essential for an optimal T cell response to influenza, in this work from @mariekedoesscience.bsky.social and colleagues at @crgglasgow.bsky.social:
www.mucosalimmunology.org/article/S193...
02.06.2025 14:09 β π 9 π 1 π¬ 0 π 1
19.06.2025 11:20 β π 1 π 0 π¬ 0 π 0
Vaccination against helminth IL-33 modulators permits immune-mediated parasite ejection
The murine intestinal nematode Heligmosomoides polygyrus bakeri (Hpb) modulates the host immune response via the Hpb alarmin release inhibitor (HpARI)β¦
π¨ New McSorley lab paper just out in Cell Reports!
Very happy to see this published - it has been a lot of work, and its turned into a really nice story.
In it, we show that HpARI+HpBARI can be used as vaccines
Tutorial thread below (1/16):
www.sciencedirect.com/science/arti...
22.05.2025 10:42 β π 27 π 7 π¬ 2 π 1
So excited to share our first neuro focused paper from the lab, we show that CXCL4 (PF4) is transported into the brain by proteoglycans within the endothelial glycocalyx and that GAG binding also mediates the pro neurogenesis effects of CXCL4. www.biorxiv.org/content/10.1...
28.04.2025 07:41 β π 63 π 19 π¬ 4 π 3
The tetanus vaccine has saved an astonishing 27.9 million lives - roughly equivalent to the entire population of Australia π¦ bit.ly/4ig1KAm
Read more about the success of the tetanus vaccine in our latest #CelebrateVaccines blog!
π bit.ly/42CgrZN
14.04.2025 09:34 β π 4 π 1 π¬ 0 π 0
With decorative wheeliebins π
09.04.2025 17:38 β π 0 π 0 π¬ 0 π 0
Sun's out π In case anyone is in need of a dog picture in their feed πΆπ #DogsOfBluesky
09.04.2025 17:38 β π 14 π 0 π¬ 2 π 0
Labβs latest: (mouse) mums grow their guts during pregnancy and lactation: www.cell.com/cell/fulltex...
19.03.2025 17:31 β π 152 π 60 π¬ 14 π 5
Screen shot of a Google search confirming that the 2025 Spring equinox falls on 20th March at 9:01.
How about a tiny touch of good-fulness to counter the awfulness.
By both astronomical and meteorological measures, at 9:01 today it will be officially Spring.
πͺ»
20.03.2025 06:32 β π 57 π 26 π¬ 2 π 3
Finally pulled the deactivate button on twitter π Will miss #ScienceTwitter but very glad mostly everyone is here π
18.03.2025 08:08 β π 7 π 0 π¬ 0 π 0
Challenge accepted π Love this
10.03.2025 10:47 β π 1 π 0 π¬ 0 π 0
The man with the golden arm
A short tale of immunology and one man's incredible commitment.
A little immunology story celebrating the legacy of James Harrison- something positive in amongst the gloom π§ͺ
05.03.2025 17:46 β π 90 π 21 π¬ 5 π 1
Macrophages promote collagen deposition through circadian regulation of fibroblasts
Collagen deposition in fibroblasts, the primary collagen-producing cells, is regulated by both macrophages and the circadian rhythm, although how these regulatory processes interact with one another i...
Our lab's #1st manuscript from our #1st #PhD Katie is on #bioRxiv! Check it out ππ»
#macrophage regulation of fibroblast #collagen #circadian rhythm. #ImmunoECMatrix w/ @profandrewmac.bsky.social @tracyh9494.bsky.social @mcrcellmatrix.bsky.social @mcf-uom.bsky.social
www.biorxiv.org/content/10.1...
05.03.2025 08:28 β π 52 π 18 π¬ 0 π 1
Poster day! Please come and chat later at poster 2036 #ksmyeloid25
05.03.2025 09:18 β π 6 π 1 π¬ 0 π 0
Lunchtime view π #ksmyeloid25
04.03.2025 13:46 β π 8 π 0 π¬ 0 π 0
We're based in the Ashworth Laboratories, King's Buildings, University of Edinburgh. Photo shows the main staircase in the entrance to the Ashworth, stone steps from the 1920s, decorated with a series of bright, colurful banners depicting the science that's tackled in the building.
I'm very pleased to have two lab positions open this week, to join our team looking at immune regulation in infection and co-infection. We're especially interested in tissue-based immunity, cytokine regulation and immune metabolism. Join us! Postdoc (3y) and research technician (12mo) posts open.
03.03.2025 08:46 β π 63 π 58 π¬ 1 π 1
Hallo Hannover! Ready for the #KSmyeloid25 @keystonesymposia.bsky.social tomorrowπ©βπ¬
03.03.2025 20:18 β π 2 π 1 π¬ 0 π 0
πΊ My Happy Sunday Post!β£
This past Tuesday, we celebrated the π§ͺππ§πππ«π§πππ’π¨π§ππ₯ πππ² π¨π ππ¨π¦ππ§ ππ§π ππ’π«π₯π¬ π’π§ πππ’ππ§ππ π§¬πΈ. In these onerous and uncertain times for both #science and #women, letβs hold on to a bit of #optimism!
#WomenInScience
#WomenInSTEM #Diversity
#Education #Equity #Inclusion
16.02.2025 09:18 β π 94 π 27 π¬ 2 π 1
Despite the current uncertainty of being a scientist, I am excited to share our manuscript demonstrating an interesting mechanism of how swirling motion of breast cancer cells align collagen fibers radially at the tumor-stroma interface to enable their invasion (1/11) @thechaudhurilab.bsky.social
14.02.2025 07:19 β π 27 π 10 π¬ 5 π 4
π¬Our 2024 updateπ¬ on monocytes their origins and development - with @kim-lab.bsky.social and Alex Mildner - The image below uses a 'sweet shop analogy' to illustrate the plasticity of monocytes during the immune response π¬ artist Maya Rachman doi.org/10.1093/disc...
26.12.2024 07:14 β π 9 π 2 π¬ 0 π 0
Man or dog π Skye's 1st Christmas π
19.12.2024 22:28 β π 0 π 0 π¬ 0 π 0
IT'S OFFICIAL! From today, @plos.org and its journals are no longer posting on Twitter/X. If you want to carry on hearing about great science in our journal, follow @plosbiology.org on Bluesky here: bsky.app/profile/plos...
16.12.2024 18:59 β π 1097 π 309 π¬ 13 π 17
There's still time to apply for this postdoc position in our lab. Ideally suited to someone wanting to develop some independent research, we have lots of new projects to select from! #immunosky π§ͺ
16.12.2024 11:03 β π 23 π 26 π¬ 0 π 1
Still going @@crgglasgow.bsky.social ππ
12.12.2024 18:11 β π 4 π 0 π¬ 0 π 0
I made a starter pack for mammary developmental and cancer biologists.
Tell me if you want to be added or suggest colleagues.
go.bsky.app/8ZbyV6c
23.11.2024 13:15 β π 28 π 11 π¬ 7 π 0
Studying cellular #stress responses, particularly #senescence and its impact on #immune response, #ageing and #cancer, #tumorigenesis at Cancer Research UK CI βͺ@cruk-ci.bsky.socialβ¬, University of Cambridge βͺ@cam.ac.ukβ¬
Website: naritalab.com
Advancing our understanding of human autoimmunity and transforming patient lives through bold, collaborative, and translational science.
Learn more: www.coltonconsortium.org
Researchers at the University of Birmingham, Centre for Liver and Gastrointestinal Research, UK
Principal Scientist Bioinformatics @ Gilead Sciences, Oxford UK
Wellcome ECA Fellow in the Harding Lab at the #WCIP. Interested in nutrient regulation in Toxoplasma. She/Her. π³οΈβπ
π¬π§ in πΊπ². Immunologist studying glioblastoma at Duke. Grimsby Town fan. Crochet & knitting enthusiast. She/her.
Husband, father & son | neonatologist & immunologist | Colombiano & Latinx
Radiation oncologist, inflammatory breast cancer doctor and researcher at MDACC (posts are my own). #medsky #radonc #bcsm #oncsky #cansky #radoncsky
Mammary Development and Breast Cancer Lab at Michigan State University
Astrophotography, nature and Triathlon posts too.
https://lab.andrechek.com/ #bcsm #oncsky
My laboratory @ethzurich.bsky.social at ETH ZΓΌrich is working towards engineering functional tissues for regenerative medicine. Our tools include bioprinting, hydrogel design and gene editing of cells.
We are a translational research team dedicated to unraveling the mysteries of the NF1 gene
Developmental Neurobiologist looking for opportunities to start a lab!
Scott Williams Lab | Center for Gastrointestinal Biology and Disease
UNC Chapel Hill | Durhamite
#devbio #gut-brain
Understanding how past infections and inflammatory insults affect subsequent immune responses
Field station of the School of Biodiversity, One Health & Veterinary Medicine (@UofGSBOHVM.bsky.social), University of Glasgow (@uofglasgow.bsky.social) on Loch Lomond. Research & teaching, aquatic and terrestrial ecology, evolution, behaviour & more!
The Canadian Society for Immunology strives to support #immunology research and education across Canada π¬π¨π¦
Account run by the CSI Trainee Engagement Committee
https://www.csi-sci.ca
Immunologist working at the Baker Heart and Diabetes Institute | chronic inflammation and adaptive immunity | Celtic fan
New center at National Institute of Chemistry in Slovenia focused on translational research of gene and cell therapies for #RareDisease and #Cancer, funded by the EU, the Slovenian Ministry of Higher Education, Science and Innovation, and UKRI.