Chemokine Research Group

Chemokine receptor expression defines a trajectory from monocytes to mature macrophages CCR1, CCR2 and CCR5 direct recruitment of monocytes and macrophages in inflammation. However, the discrete role for each receptor in monocyte/macrophage biology remains poorly understood, with previou...

Our CRG newest preprint! Please read and share 😀
www.biorxiv.org/content/10.1...

03.11.2025 15:47 — 👍 0    🔁 1    💬 0    📌 0

Macrophages drive inguinal fat pad and lymph node remodelling in response to peripheral inflammation. Adaptive immune responses are intensely energy-dependent and rely on a local source of fuel-producing molecules which have been proposed to be derived from fat pads in which mammalian lymph nodes are ...

Our newest preprint is out now! Great work by Dr Robin Bartolini on how "Macrophages drive inguinal fat pad and lymph node remodelling in response to peripheral inflammation." www.biorxiv.org/content/10.1...

07.10.2025 14:41 — 👍 2    🔁 0    💬 0    📌 1

Book cover “teach your cat Welsh”

It’s been such a pleasure working as part of @crgglasgow.bsky.social
So many amazing colleagues, collaborators and friends over the years, thanks everyone!
And how to better prepare for my next adventure as Wales Applied Virology Unit (WAVU) lecturer than with this amazing present from them.

09.09.2025 10:07 — 👍 5    🔁 1    💬 0    📌 0

Not all chemokine signaling is about cell migration!

In mouse erythroblasts, CXCL12-bound CXCR4 enters the nucleus to control gene transcription, trigger calcium bursts, and drive red blood cell formation—especially enucleation.

🔗 science.org/doi/10.1126/sc…
#chemokine #CXCR4

21.06.2025 17:11 — 👍 23    🔁 13    💬 3    📌 0

New paper alert! Excited to share our latest work on the importance of inflammatory #chemokine receptors (iCCR, aka the best chemokine receptors) in mounting an optimal T cell response to #influenza infection.

Please share, happy to discuss!

02.06.2025 16:07 — 👍 5    🔁 2    💬 1    📌 0

Brilliant time as always at our @crgglasgow.bsky.social away day at @sceneuog.bsky.social

19.06.2025 11:19 — 👍 4    🔁 2    💬 1    📌 0

So excited to share our first neuro focused paper from the lab, we show that CXCL4 (PF4) is transported into the brain by proteoglycans within the endothelial glycocalyx and that GAG binding also mediates the pro neurogenesis effects of CXCL4. www.biorxiv.org/content/10.1...

28.04.2025 07:41 — 👍 66    🔁 20    💬 4    📌 3

Inflammatory chemokine receptors CCR1, CCR2, CCR3 and CCR5 are essential for an optimal T cell response to influenza. Inflammatory chemokine receptors CCR1/2/3/5 (iCCRs) play an important role in the recruitment of immune cells involved in innate immune functions and orchestrating the adaptive immune response. Here w...

Some nice new reserach from @mariekedoesscience.bsky.social and @crgglasgow.bsky.social studying the inflammatory CCR locus and immune responses to influenza. www.biorxiv.org/content/10.1...

24.03.2025 08:32 — 👍 7    🔁 5    💬 1    📌 1

Poster day! Please come and chat later at poster 2036 #ksmyeloid25

05.03.2025 09:18 — 👍 6    🔁 1    💬 0    📌 0

Amanda E.I. Proudfoot Tribute Award for Advances in Chemokine Biology by a Trainee - International Cytokine & Interferon Society Nomination/Application Form Submission Deadline: 15 May, 2025 ICIS welcomes donations to fund the Amanda E.I. Proudfoot Tribute Award (click the Donate button below and then choose the Amanda Proudfoo...

Can you please spread the word re: Amanda Proudfoot Tribute Award for Advances in Chemokine Biology by a Trainee cytokinesociety.org/amanda-e-i-p.... Donations are also accepted to help fund this Annual Award for those interested in Chemokine Biology. Submission Deadline is 15 May for Cytokines 2025

17.12.2024 15:41 — 👍 0    🔁 1    💬 0    📌 0

Amanda Proudfoot Tribute Award for Advances in Chemokine Biology by a Trainee cytokinesociety.org/amanda-e-i-p... Donations are also accepted to help fund this Annual Award for those interested in Chemokine Biology. Submission Deadline is 15 May for Cytokines 2025 in Seattle @crgglasgow.bsky.social

17.12.2024 15:48 — 👍 5    🔁 3    💬 0    📌 0

Share all your papers!!! Give descriptions so people will engage. Scientists should not rely on pubmed and talks alone to share their information.

03.12.2024 15:09 — 👍 14    🔁 1    💬 0    📌 0

Our 1st BlueSky post and it's our lab's newest preprint! Please read and share and let us know any of your thoughts 😊 #chemokine #immunosky

03.12.2024 14:57 — 👍 8    🔁 1    💬 1    📌 1