Carlos Henrique Pereira

What a week! Full of learning, new ideas, and inspiring conversations. I met so many brilliant and kind people, and I’m leaving with fresh perspectives. Thanks @nitmb.bsky.social

Multielectrode arrays can be used to investigate electric activity (field potential duration, conduction velocity, arrhythmic substrates, etc.) in cardiac tissue and cells. Useful to investigate the effect of diseases and drugs. 🧪

Hi Chris.. I'm glad the cell isolation is working.

Perfectly put, we are not a jar of organs. We are a prime example of the saying "the whole is more than the sum of its parts". In out lab we have now data indicating not only a gut-heart axis but also a gut-brain-heart axis. We hope to publish this findings by the end of the year

Ever wondered about the heart-gut connection in inflammatory bowel disease? Our brand new paper reveals insights into atrial electrophysiology changes during active ulcerative colitis that may explain the higher risk of arrhythmias in IBD patients.
🧪

www.mdpi.com/2218-273X/15...

Thanks!

Hi.. The link doesn't seem to be working.

Calcium transient imaging using an @ionoptix.bsky.social setup. On the bottom of the screen we can the pretty cardiomyocyte "beating". 🧪

Calcium imaging in cardiomyocytes is a method used to measure intracellular calcium levels and assess calcium dynamics. It is a powerful tool for investigating the effects of diseases and drugs on cardiac electrophysiology and contraction, providing insights into the mechanisms of arrhythmias.
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Massa...

Ficou mto massa....

Studies have shown that both IBDs increases the propensity for arrhythmia, hypertension, etc. Specially during the flare ups. But, in patients, it's difficult to know the exact cause (confounders). It's good you have been monitoring it with a doctor. Only them can provide diagnose and treatment.

Colitis induced ventricular alternans increases the risk for ventricular arrhythmia Inflammatory bowel disease was linked to an increased risk for conduction defects and ventricular arrhythmia. It coincides with dysregulation of gut microbiota, increased inflammation, and deregulatio...

I'm thrilled to announce the publication of my newest paper in JMCC, which investigates the mechanism of ulcerative colitis induced ventricular arrhythmias 🧪

www.jmcc-online.com/article/S002...

Hi Monica. I'd like to be added to the feed. PhD in Physiology ☝️.
Sharing my orcid and researchgate links.

ORCID:
orcid.org/0000-0001-86...

Researchgate:
www.researchgate.net/profile/Carl...

An interesting story about the psychology of changing people's minds, with a dash of data visualization. ♾️

Terapia, umas boas férias num lugar tranquilo pra deixar a cabeça mais vazia.

Curitiba, Brazil, offers another compelling example of the benefits of going car free. In the 1970s, Mayor Jaime Lerner defied local business owners by pedestrianizing XV de Novembro street. Contrary to their fears that it would harm their businesses, the opposite occurred. Business thrived!

Honestly, it puzzles me why that stretch of Lincoln Ave isn't permanently closed to cars. It is a small gem of an area that would greatly benefit from being car free.

Very nice graph. If the data represents the US, a comparison with Brazil, which experiences summer and Carnaval in February, could be quite insightful. I'll try to find data from Brazil 🇧🇷

So happy to see my wonderful city featured on this list! It filled me with memories of its fragrant eucalyptus trees and the charming black and white cobblestone sidewalks. I really miss my beloved Curitiba

But right now I am still intrigued by the period doubling I found, and how complex "behavior" can arise even from a simple network.

Next I'll try to reproduce results from a paper published by Stephen Lipius group (don't know if you met him at loyola) where acetylcholine elicits a rebound stimulation of calcium current. That will be a little harder, I think!

I recently attended the Netflux and Logic-Based Network Biology virtual conference organized by @jsauce7.bsky.social . Here's my first attempt at logic-based simulations. I've exported the simulation data to customize the graph further using R. Excited to explore more!

Early pathological mechanisms in a mouse model of heart failure with preserved ejection fraction | American Journal of Physiology-Heart and Circulatory Physiology | American Physiological Society Heart failure with preserved ejection fraction (HFpEF) constitutes more than half of all HF cases, yet evidence-based therapies remain lacking due to limited understanding of its underlying pathologic...

Excited to share a recent paper I had the previlege to co-author. Thanks Dr. Rosas for the opportunity. 🧪 🔬 🧬 #physiology
- I couldn't find the other authors here on bluesky.

journals.physiology.org/doi/full/10....

I am reading it right now

Intense game... 😌

Awesome 🤮