Abdul Razak

Compromised cardiopulmonary transition in fetal growth restricted and small for gestational age neonates Abstract figure legend Differences in cardiovascular function between appropriately grown (AG) and fetal growth restricted (FGR) infants after the cardiopulmonary transition at birth. AG infants typi....

NEW PAPER

Compromised cardiopulmonary transition in fetal growth restricted and small for gestational age neonates

Suboptimal fetal growth → altered cardiac structure/function → higher risk of impaired adaptation at birth, respiratory morbidity, and long-term CV risk.

doi.org/10.1113/JP28...

Cord blood-derived cell therapy for preterm brain injury Preterm birth, defined as delivery before 37 weeks of gestation, remains a leading contributor to neonatal morbidity and long-term neurodevelopmental …

New publication from our group covering aspects of the talk I will be giving at Neonatal Update in London later this year.

Cord blood-derived cell therapy for preterm brain injury
www.sciencedirect.com/science/arti...

@drabdulrazak.bsky.social @courtney-mcdonald.bsky.social

Persistent inflammation and white matter damage in the preterm brain: Insights from a novel ovine model of chronic inflammation - PubMed We demonstrated that in a large animal model of inflammation-induced intrauterine preterm brain injury, long-term persistent inflammation occurs, along with significant white matter injury, including ...

New preclinical paper from our team on a new long term model of inflammation induced preterm brain injury.

pubmed.ncbi.nlm.nih.gov/40714018/

@drabdulrazak.bsky.social @courtney-mcdonald.bsky.social @hudsonresearch.bsky.social

Early Neurodevelopment of Extremely Preterm Infants Administered Autologous Cord Blood Cell Therapy

Secondary Analysis of CORD-SaFe study now out in @jamanetworkopen.com

jamanetwork.com/journals/jam...

@drabdulrazak.bsky.social @courtney-mcdonald.bsky.social @hudsonresearch.bsky.social

Postextubation use of non‐invasive respiratory support in preterm infants: a network meta‐analysis - Razak, A - 2025 | Cochrane Library Select your preferred language for Cochrane reviews and other content. Sections without translation will be in English.

Glad to share our 2 Cochrane network meta-analyses investigating use of 7 diff. non-invasive respiratory support in preterm infants

Post-extubation www.cochranelibrary.com/web/cochrane...

Primary www.cochranelibrary.com/web/cochrane...
@ebneo.bsky.social @monashuniversity.bsky.social

Tiny warriors to the rescue! 💥

Matched stem cells from healthy newborns donated at birth now being trialed to help preterm babies with severe brain injury @monashuniversity.bsky.social

Protocol just out
@atulmalhotra.bsky.social @courtney-mcdonald.bsky.social
bmjopen.bmj.com/content/bmjo...

More isn’t always better!

Adding systemic hydrocortisone to intrapulmonary budesonide in preterm ventilation didn’t boost lung outcomes—in fact, it blunted the benefits & triggered early brain inflammation

Commentary: rdcu.be/eraxD

Study: nature.com/articles/s4139…
@atulmalhotra.bsky.social

When we see parents doing kangaroo care, we should sincerely thank them as this simple act is saving lives!

New SRMA published in @lancetchildadol.bsky.social confirms this intervention as high quality evidence in reducing death
www.thelancet.com/journals/lan...
@ebneo.bsky.social

New meta-analysis on PDA management suggesting harm associated with active treatment compared to expectant management
jamanetwork.com/journals/jam...

Thanks Beth

Feeling incredibly proud to receive the @theracp.bsky.social
Fellowship Award in support of ongoing PhD work!

Grateful to be part of a brilliant research team driving this forward!
@atulmalhotra.bsky.social @courtney-mcdonald.bsky.social @monashuniversity.bsky.social

Thrilled to share our latest article spotlighting the emerging power of umbilical cord blood cells in treating neonatal diseases!

A great read and a promising start for UCBC applications
@atulmalhotra.bsky.social
publications.aap.org/neoreviews/a...

Association Between Hammersmith Infant Neurological Examination and Bayley Scales of Infant Development in High‐Risk Infants: A Retrospective Cohort Study Click on the article title to read more.

Association Between Hammersmith Infant Neurological Examination and Bayley Scales of Infant Development in High-Risk Infants: A Retrospective Cohort Study onlinelibrary.wiley.com/doi/full/10....

@drabdulrazak.bsky.social

“There was no significant difference between the
eCPAP and dCPAP groups with regards to the time to first feed or full feeds, occurrence
of BPD as defined by Jobe and Bancalari (7.4%vs 6.5%), or discharge PMA between
the groups.”

Extended Continuous Positive Airway Pressure in Preterm Infants Increases Lung Growth at 6 Months: A Randomized Controlled Trial - PubMed gov, ID: NCT04295564.

Full text here pubmed.ncbi.nlm.nih.gov/39977011/

Extended Continuous Positive Airway Pressure in Preterm Infants Increases Lung Growth at 6 Months: A Randomized Controlled Trial - PubMed gov, ID: NCT04295564.

pubmed.ncbi.nlm.nih.gov/39977011/

Extended Continuous Positive Airway Pressure in Preterm Infants Increases Lung Growth at 6 Months: A Randomized Controlled Trial - PubMed gov, ID: NCT04295564.

pubmed.ncbi.nlm.nih.gov/39977011/

Lungs need pressure to grow!

RCT demonstrates extended CPAP promotes lung growth and gas exchange
#neoEBM @ebneo.bsky.social
atsjournals.org/doi/10.1164/rc…

Wow

All feeds by D1-2 is amazing in 28 w plus above cohort

Donors milk (if EBM not much) I presume?

Until what age you have provisions for donor milk?

What’s your NEC rates in >28w cohort?

Welcome Ted - glad to have you here. See you soon.

Yes looking forward to see it

I’m assuming they will show the data at PAS

Just help me understand this - do you mean you have been practicing this already in DK for >28 week GA babies

Yes that’s what happens most places but this small RCT demonstrates babies 30-33w could be all feeds enterally from day 1

Saves lot of money and costs

Of course need big trial to demonstrate safety as well - FEED1 trial has completed recruitment analysis on way

We could feed 30-33 week babies exclusively enterally from day 1 with no TPN or IV fluids which results in many gains including shorter hospital stay by almost 1 week as demonstrated in this RCT
@ebneo.bsky.social
t.co/5byENdNLlU

Preprint (not peer-reviewed) of the next CORD-SaFe paper is out:

Early Neurodevelopmental Outcomes of Extremely Preterm Infants Administered Autologous Cord-Blood Derived Cell Therapy
papers.ssrn.com/sol3/papers....

Lindsay Zhou @drabdulrazak.bsky.social

Attending #PAS2025?

Don't miss our workshop on Evaluating Trustworthiness: Identifying Spin, Fraud, and Deception in Modern Research

Date: Friday, April 25, 2025
Time: 4:00 PM - 5:30 PM

@ebneo.bsky.social
Rasheda Vereen @atulmalhotra.bsky.social @briankingneo.bsky.social @drabdulrazak.bsky.social

😅

Thanks Kent

Also - check out our workshop entitled "Evaluating trustworthiness: identifying spin, fraud and deception in modern research" on Friday at 4:00 pm with @drabdulrazak.bsky.social, Rasheda Vereen and Atul Malhotra @ebneo.bsky.social

Glad to share the PhD project on persistent inflammation in a novel intrauterine ovine model is selected for oral presentation

It also gets Trainee Award🎊

See you all at Hawaii
@atulmalhotra.bsky.social @courtney-mcdonald.bsky.social @monashuniversity.bsky.social