Jason Bini, PhD

Looking to recruit a postdoc for a June 1 or later start date. Details below. Familiarity/experience in PET imaging and quantification is most desired.

Frontiers | Morphological and functional alterations in type 2 diabetes pancreata assessed with MRI-based metrics and [18F]FP-(+)-DTBZ PET ObjectiveTo determine if combining PET-derived beta-cell mass (BCM) estimates with MRI-based morphology metrics improves the prediction of beta-cell function...

Update - the final peer-reviewed version of the manuscript is out!
We examined combined utility of PET/MR pancreas imaging metrics in type 2 diabetes.
@yalebiomedimaging.bsky.social

www.frontiersin.org/journals/end...

Trifecta achieved this week: High fat cheese and lower dementia risk, naps and big brains and exercise mediates alcohol risk.

Longitudinal, simultaneous wide-field fluorescent Ca2+ imaging and fMRI in awake mice Functional magnetic resonance imaging (fMRI) can be applied in mice and humans making it a key technology in translational neuroimaging research. Yet, most neuroimaging studies in rodents use anesthes...

Talking about spooky stuff…try to do awake mouse fMRI.
Oh, you want it spookier? Try to add simultaneous Ca2+ imaging.

Now, do it all again, longitudinally….

So proud to finally have this out!!!
🐭 🧠 🧲
Go read…if you dare!! 👻

www.biorxiv.org/content/10.1...

Not entirely convinced reviewers 1 and 2 even read our manuscript...

Today!

Imagine my excitement reading this title only to find out it's not *that* IPA 🍺😂

Hey that's us! First official Bini lab preprint 🎉

Issues | Cerebral Cortex | Oxford Academic Publishes papers on the development, organization, plasticity, and function of the cerebral cortex, including the hippocampus.

A birthday is a good time to reflect! To mark SPM @ 30, this month's issue of Cerebral Cortex features deeply insightful commentaries on neuroimaging analysis from Ed Bullmore, Peter Bandettini, Peter Fox, Pedro Valdes-Sosa, Klaas Enno Stephan, Viktor Jirsa, et al [1/2] academic.oup.com/cercor/issue

If you haven't seen it yet, check out our article highlighted Up Front as an editors pick in the @DiabetologiaJnl September issue!

With boost to NIH budget, Senate panel rejects Trump’s plan to slash agency Republicans on spending committee push back against proposed reorganization and overhead cuts

The National Institutes of Health’s budget, and structure, would be preserved under a Senate bill for the 2026 fiscal year.

NIH is shrinking the number of research projects it funds due to a new Trump policy NIH plans to shrink the share of grant applications it will award for the remainder of the fiscal year, in some cases by more than half.

NIH plans to shrink the share of grant applications it will award for the remainder of the fiscal year, in some cases by more than half.
www.statnews.com/2025/07/29/n...

Odds of winning NIH grants plummet as new funding policy and spending delays bite Funding multiyear grants up front will sharply cut number of investigators receiving awards

"Concerns are rising that President Donald Trump’s administration is finding new ways to shrink the U.S. biomedical research enterprise [right now]"

Great article from @jocelynkaiser.bsky.social at @science.org
🧪

🚨 Required reading for every scientist, academic admin, and member of Congress 🚨

The shift to multi-year funding is a Trojan Horse designed to cannibalize NIH funding with zero congressional oversight

The effects will be immediate. paylines will crater, labs will shutter, Americans will suffer. 🧪

We hope this review provides a call to researchers to pursue further studies examining brain glucose metabolism and a roadmap of how this can be done with PET and MRS.

Within a range of physiologically relevant plasma concentrations; plasma and brain glucose scale linearly. In the limited number of studies in T2D/obesity, this relationship seems to diverge. Conclusions based around CMRglc in T2D/obesity also vary and would benefit from further studies.

Very excited for this review to be out! A dive into PET/MRS techniques for measuring brain glucose concentrations and cerebral metabolic rate of glucose in the context of diabetes and obesity. #neuroimaging #obesity #diabetes #metabolism #neuroendocrinology

link.springer.com/article/10.1...

DOGE is now reviewing every NIH grant that goes out, I reported last week.

That review is AI-driven and is screening for DEI, trans health, China, vaccine hesitancy, and the institutions to whom Trump has blocked funding, @hannahnatanson.bsky.social reports.

Gift link: wapo.st/3HhnPSt

Opinion | Universities and the government: Which needs the other more? From public health to high-tech innovation, universities are the workhorses of national progress.

Universities are not passive beneficiaries of government largesse. It is the federal government that depends on universities to conduct the research that keeps our nation healthy, safe and economically competitive.I discuss in the Washington Post.
www.washingtonpost.com/opinions/202...

The university endowment tax in the Republican/Trump economic plan sets a dangerous precedent of the government slapping excessive taxes on institutions it disagrees with ideologically. It also will cause cuts in jobs, financial aid and research funding. wapo.st/3HiYtDv

The "Make America Health Again" Report has the word "obesity" in it 51 times and yet the primary US institute that researches the impact and new treatments for obesity (NIDDK) would be sure to have their budget cut under the current spending bill or the White House recs (40% cut to the NIH budget).

Obviously, the mission of universities should be education but let's not lie to ourselves and say big time college sports, a uniquely American thing, is not something a vast majority of the population celebrates and participates in, either playing or spectating.

It's not a fully formed thought but someone needs to connect the collapse of universities/colleges all across the country with the collapse of the sports (scholarships) industrial complex. I would guess a HUGE economy is kids sports in hopes of playing big time college sports.

Could be huge. Especially for those terminated in the anti-DEI purge.

"...NIH will allow individuals whose mentored career development awards prematurely ended on or after January 1, 2025, to be eligible to apply for a new mentored career development award"

grants.nih.gov/grants/guide...

NIH killed grants on orders from Elon Musk’s DOGE Court documents and internal correspondence show the cost-cutting force has broad control over the world’s largest public biomedical funder.

Sworn testimony of NIH officials and internal emails reveal just how much DOGE is calling the shots in killing peer-reviewed biomedical research grants. More bombshell reporting from @maxkozlov.bsky.social in @nature.com:

"Women are PIs on 58% of the canceled grants, although they are PIs on only 34% of all active NSF grants.

Similarly, Blacks are PIs on 17% of the terminated grants, although they make only 4% of the total pool. Hispanic PIs and those with disabilities were twice as likely to lose a grant."

Graphic of Washington Post poll from April 18-22, 2025, showing "Majorities of Americans oppose various Trump proposals" highlighting two lines in particular: "Increasing the Federal Government's role in how private universities operate" - 28 percent support, 70 percent oppose "Reducing federal funding for medical research" - 21 percent support, 77 percent oppose

University leaders need to understand: they are holding INCREDIBLY good cards.

It is so rare in today's polarized era to have the support of 70+ percent of the public against the Trump admiministration on anything. Universities have that—AND winning legal arguments.

Opthalmology Chic. Keeping that eye health in check!

Thanks to The Grey Matter Project, Sreya and Prof Sara Schaefer for the invite and organizing! Really fun to talk to the HS students who are the next generation of Drs and researchers about neuroendocrinology.
medicine.yale.edu/neurology/ed...

Leading Nutrition Scientist Departs N.I.H., Citing Censorship (Gift Article) Kevin Hall said his work on ultraprocessed foods has been “hobbled” under the Trump administration. Scientists have been raising such concerns for months.

My story about @kevinh-phd.bsky.social, nutrition and metabolism scientist at N.I.H., who felt compelled to take early retirement after experiencing censorship of his work under the new administration. www.nytimes.com/2025/04/16/w...