Justin Taraska

Breaking Fundamental Biological Law: Research by Takashi Akera Investigates Selfish DNA - Vilcek Foundation Winner of the Vilcek Prize for Creative Promise, Akera’s novel research findings have huge implications for infertility and chromosomal disorders.

vilcek.org/news/breakin...

Figure showing the comparison between spinning disk (SD) confocal, SIM and ExM when imaging Drosophila cemtrioles.

Emma Burns, Anastasia Amoiroglou, Gregory Rogers, Nasser Rusan and colleagues develop an expansion microscopy protocol for Drosophila cultured cells and tissues, which they use to dissect centriole biology.
journals.biologists.com/jcs/article/...

Prime numbers 2-4999, animated with ggplot2+gganimate.

#Rstats code: gist.github.com/stephenturne...

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Laboratory Engineer (Senior), in Advanced Imaging, 1.5.2026-31.12.2028

🚨 Job Alert! 🚨

We have an opening at our Microscopy Core Facility in Turku 🇫🇮.
If you love imaging 🔬 and helping scientists succeed, we want you! 👇

abo.rekrytointi.com/paikat/index...

#Microscopy #ScienceJobs #CoreFacility #Imaging
@turkubioscience.bsky.social

DC, Winter 2025

My lab in the NIH Intramural Program (Bethesda, MD) will be recruiting postdoctoral fellows over the next year with flexible start dates. We work on nanoscale cellular imaging of the plasma membrane and related organelles. Please reach out if you’re interested. www.training.nih.gov/jobs/pdp-053...

A conformational switch in clathrin light chain regulates lattice structure and endocytosis at the plasma membrane of mammalian cells - PubMed Conformational changes in endocytic proteins are regulators of clathrin-mediated endocytosis. Three clathrin heavy chains associated with clathrin light chains (CLC) assemble into triskelia that link into a geometric lattice that curves to drive endocytosis. Structural changes in CLC have been shown …

We have a number of fluorescent protein pairs here that are great for FLIM www.addgene.org/browse/artic...

Yes! Many of our plasmids are here www.addgene.org/Justin_Taras... and both NPY-GFP (exocytic vesicles) and clathrin light chain-GFP (endocytic sites) make excellent sub-diffraction biological targets.

MBL Announces Largest Ever Gift for Its Renowned Biological Education and Research Programs | Marine Biological Laboratory Cell Biology Researcher Mark Terasaki’s $25 Million Unrestricted Gift Will Support Operations and Infrastructure Contact: Samantha Cummis scummis@mbl.edu; 973.800.4119

We're thrilled to announce the largest private gift in our 137-year history: a $25 million unrestricted donation from MBL Whitman Scientist Mark Terasaki.

His extraordinary generosity will bolster our renowned research and education programs. 🔬

Learn more: bit.ly/452WL1m

Hoya bloom

Woods Hole, MA

Salt Lake from the air

Metro

Japanese Garden, Powell’s Bookstore downtown, Forest Park, SE Division or SE Hawthorne St, Coava coffee, OHSU gondola.

I am excited to share our first Pt replica EM images. It took us a little while, but now we have establish the unroofing, drying and Pt coating workflow 🎉 Great work by our postdoc Luis Wong Dilworth! The image below shows the cytosolic membrane leaflet of a fibroblast 👇

Super cool. Septin/actin rings maybe.

This is a scientific figure from the paper mentioned in the post. It shows fluorescence and electron microscopy images and associated schematics for using the ferritag to image clathrin coated pit proteins.

I'd like to draw your attention to this truly excellent paper from the Taraska lab on cryoET of plasma membrane associated proteins. Everyone who is thinking about probes in the cryoET space should also see what they could do with ferritag (fig 6) www.nature.com/articles/s41...

Physiology: Modern Cell Biology Using Microscopic, Biochemical and Computational Approaches | Marine Biological Laboratory This course is at the forefront of new tools — molecular, computational, biophysical — as it prepares students to tackle emerging biological questions.

The deadline to apply for the MBL Physiology course is fast approaching, January 27th! Consider applying to this amazing, life-changing research discovery experience in Woods Hole! www.mbl.edu/education/ad...

Not necessarily unhappy. Muscle cells have extensive flat clathrin lattices. Some cells stimulated with EGF also have them. Highly metastatic cells can accumulate them. They are used as adhesion and receptor organization sites.

Is the third image at the bottom surface of the cell? Those are likely large flat clathrin lattices that can accumulate in some cell types at the bottom of the cell.

CD44 and Ezrin restrict EGF receptor mobility to generate a novel spatial arrangement of cytoskeletal signaling modules driving bleb-based migration https://www.biorxiv.org/content/10.1101/2024.12.31.630838v1

It’s incredibly exciting when a completely different approach supports an unexpected finding from your group. Recently, we published that LDLR is captured with EGFR and FGFR1 at clathrin sites after EGF stimulation. I love science.

www.molbiolcell.org/doi/full/10....

bsky.app/profile/scie...

Extracellular proximal interaction profiling by cell surface–targeted TurboID reveals LDLR as a partner of liganded EGFR A modified form of TurboID identifies extracellular interactions between transmembrane proteins.

In a new #ScienceSignaling study, researchers introduce extracellular #TurboID, a refinement of the popular proteomics tool that interrogates #ProteinProteinInteractions on the exterior cell membrane, and characterize interactions between #EGFR and #LDLR. scim.ag/3DgfJr9

Condolences Rita, I’m so sorry.