Roy Matkovic

Pleased to announce launching Institut Cochin Foundation, on Sept. 18 at 6 p.m., upon registration, either in the Rosalind Franklin room, 22 rue Méchain, Paris or via video conference: presentation of @institutcochin.bsky.social, meet researchers and call for donations-thanks for your support!

Zeus had his Hydra ⚔️, now Toxoplasma has its own.

Meet Hydra: not a monster, but a brand-new protein domain.
It multimerizes like crazy & rewrites the chromatin landscape 🧬 in Toxoplasma.

Our team and colleagues from @embl.org #Grenoble just dropped the preprint 👉
www.biorxiv.org/content/10.1...

LINE-1 retrotransposons mediate cis-acting transcriptional control in human pluripotent stem cells and regulate early brain development Adami et al. demonstrate that evolutionarily young L1s are expressed in human pluripotent stem cells and are dynamically regulated throughout neural differentiation. The study examines the role of L1s...

New paper from our lab! We found that LINE-1 transposons contribute to early human brain development.

Funded by @asapresearch.parkinsonsroadmap.org

www.cell.com/cell-genomic...

Still 1 month to submit your abstract! Don’t miss the chance to participate in our next #POHaD symposium. Join us onsite/virtually on Oct 16th, 2025 at @institutcochin.bsky.social (Paris 🇫🇷). Registration is free but mandatory 🗓️
@juliecocquet.bsky.social #epigenetics #dohad #offspringhealth

Thrilled to receive an @agencerecherche.bsky.social JCJC grant to explore chromatin-driven antiviral defenses and to revisit some of the underlying principles behind the HUSH complex. Exciting times ahead @institutcochin.bsky.social

Merci Mick!

Merci Catherine!

Merci Caro!

Postdoc positions open in my lab (Francis Crick Institute) to study

1. initiation of DNA replication.

2. chromatin replication/epigenetic inheritance.

Great for biochemists, biophysicists and cryo-EM/cryo-tomography scientists.

Deadline 3 August 2025.

crick.wd3.myworkdayjobs.com/External/job...

Merci Sebastien!!

I warmly thank my lab for their support, and everyone whose path crossed mine along the way.

I had the privilege of defending my HDR today at @institutcochin.bsky.social, before an outstanding jury of experts @nchazal.bsky.social, @lucievirevolte.bsky.social,Rosemary Kiernan, Stephane Emiliani, Marc Lavigne. I am deeply grateful for their stimulating questions, and generous feedback.

Maîtriser la fin de la transcription : un mécanisme clé pour préserver l'intégrité du génome La transcription des gènes est un processus qui permet de copier l’information génétique contenue dans l’ADN sous forme d’ARN.

Maîtriser la fin de la transcription : identification d'un mécanisme clé pour préserver l'intégrité du génome par @fabiennebejjani.bsky.social ! 🧬

🤝 @cnrs-idf-villejuif.bsky.social‬ @inserm.fr‬ @upcite.bsky.social‬ @institutcochin.bsky.social‬

buff.ly/5hyNH7E

📣 We are recruiting new group leaders in Innovative Biology!

RNA biology
Epigenetic regulation
Cell cycle regulation
Cancer, immunology
Virology

Application and information ⬇️
application.igmm.cnrs.fr

@cnrsbiologie.bsky.social @cnrsoccitanieest.bsky.social @umontpellier.bsky.social

Mastering transcription termination: a new key mechanism to preserve the integrity of the genome Transcription termination by RNA polymerase II is essential to preserve genome integrity in eukaryotes. In their paper published in Nucleic Acids Research, the authors reveal that the SPT6 protein, in...

Discovery of a new key mechanism to preserve the integrity of the #genome!
Fabienne Bejjani et al. reveal that the SPT6 protein plays a central role in properly stopping transcription and avoiding the accumulation of abnormal transcripts.

CNRS/ Inserm/ UPC

institutcochin.fr/en/mastering...

#NSV2025 Two weeks left to register! The abstract submission/registration system on the website will CLOSE Friday, April 11, 2025. Visit www.negativestrandvirus.org/home

ARGONAUTES 2025
The grassroot meeting of Argonaute afficionados is looking for afficionados! Full coverage of Argonautes from prokaryotes to #RNAi, #piRNA and #microRNA Join us in Prague at @imgprague.bsky.social during 27-30/8, 2025. Registration, program and more info here:
argonautes.img.cas.cz

Don't forget to register and submit your abstract for #NSV2025 in Montpellier! The abstract submission/registration system on the website will CLOSE Friday, April 11, 2025.
Visit www.negativestrandvirus.org/home

Young KRAB-zinc finger gene clusters are highly dynamic incubators of ERV-driven genetic heterogeneity in mice https://www.biorxiv.org/content/10.1101/2025.02.26.640358v1

Congratulations!

Negative-Strand RNA Virus meeting #NSV2025 registration is now open!
Visit www.negativestrandvirus.org/home

#BonneAnnée 🌟 Le #CNRS vous présente ses meilleurs vœux pour l'année 2025 !

#HappyNewYear 🌟 The French National Centre for Scientific Research (@cnrs.bsky.social) wishes you the very best for 2025!

Join us! Collaborative project between 3 labs at
Institut Pasteur on tick-borne flaviviruses
research.pasteur.fr/en/job/post-...

Meta-analysis of genome wide functional screens to identify broad-spectrum antiviral and immuno-therapeutic targets Precision Medicine Project - Meta-analysis of genome wide functional screens to identify broad-spectrum antiviral and immuno-therapeutic targets

PhD opportunity in our lab at Edinburgh University! Analysing CRISPR screens for proviral and antiviral factors focusing on coronaviruses and influenza A virus. Using a mix of wet lab and computational approaches (full training provided).
#ViroSky #ImmunoSky

usher.ed.ac.uk/precision-me...

Hey Skeeters, A big new batch of our
@fnucleosome.bsky.social
seminar videos have gone public in the past couple weeks! Here's a thread:

✌🏻

May I get my membership?

May I join too? 🙏